Protein Overview: GSK3B_RAT

General Information:
Name(s) found:	GSK3B_RAT [Swiss-Prot]
Description(s) found: Found 13 descriptions. SHOW ALL	Glycogen synthase kinase-3 beta OS=Rattus norvegicus GN=Gsk3b PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	420 amino acids
Gene Ontology:
Cellular Component:	neuronal cell body [UNKNOWN] protein complex [IDA] membrane-bounded organelle [UNKNOWN] growth cone [UNKNOWN] beta-catenin destruction complex [UNKNOWN] nucleus [UNKNOWN][IDA] soluble fraction [IDA] cytoplasm [UNKNOWN][IDA][TAS] dendritic shaft [UNKNOWN] dendritic spine [IDA] membrane raft [IDA] cytosol [UNKNOWN][IDA] Axin-APC-beta-catenin-GSK3B complex [UNKNOWN]
Biological Process:	negative regulation of MAP kinase activity [IMP] fat cell differentiation [UNKNOWN] protein amino acid phosphorylation [UNKNOWN][IDA] ER overload response [UNKNOWN] re-entry into mitotic cell cycle [UNKNOWN] negative regulation of dendrite morphogenesis [IMP] anti-apoptosis [UNKNOWN] negative regulation of transcription, DNA-dependent [IDA] induction of apoptosis [IDA][TAS] regulation of neuronal synaptic plasticity [IMP] Wnt receptor signaling pathway [UNKNOWN][IEA] cell migration [UNKNOWN] positive regulation of protein complex assembly [UNKNOWN] positive regulation of peptidyl-serine phosphorylation [UNKNOWN] positive regulation of protein export from nucleus [UNKNOWN] establishment or maintenance of cell polarity [IDA] protein export from nucleus [UNKNOWN] response to stress [UNKNOWN] organ morphogenesis [UNKNOWN] glycogen metabolic process [UNKNOWN] intracellular signaling pathway [UNKNOWN] response to drug [IEP] negative regulation of apoptosis [UNKNOWN] response to lithium ion [IEP] establishment of cell polarity [IDA] positive regulation of peptidyl-threonine phosphorylation [UNKNOWN] peptidyl-serine phosphorylation [UNKNOWN]
Molecular Function:	protein kinase binding [IPI] ionotropic glutamate receptor binding [IPI] protein kinase activity [UNKNOWN] beta-catenin binding [UNKNOWN] protein serine/threonine kinase activity [UNKNOWN][IDA] glycogen synthase kinase 3 activity [UNKNOWN][IDA][TAS] nucleotide binding [IEA] tau-protein kinase activity [UNKNOWN][IDA] NF-kappaB binding [UNKNOWN] ATP binding [IDA] p53 binding [UNKNOWN] protein binding [UNKNOWN][IDA][IPI] tau protein binding [IDA] protein kinase A catalytic subunit binding [UNKNOWN] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGRPRTTSF AESCKPVQQP SAFGSMKVSR DKDGSKVTTV VATPGQGPDR PQEVSYTDTK  60
   61 VIGNGSFGVV YQAKLCDSGE LVAIKKVLQD KRFKNRELQI MRKLDHCNIV RLRYFFYSSG 120
  121 EKKDEVYLNL VLDYVPETVY RVARHYSRAK QTLPVIYVKL YMYQLFRSLA YIHSFGICHR 180
  181 DIKPQNLLLD PDTAVLKLCD FGSAKQLVRG EPNVSYICSR YYRAPELIFG ATDYTSSIDM 240
  241 WSAGCVLAEL LLGQPIFPGD SGVDQLVEII KVLGTPTREQ IREMNPNYTE FKFPQIKAHP 300
  301 WTKVFRPRTP PEAIALCSRL LEYTPTARLT PLEACAHSFF DELRDPNVKL PNGRDTPALF 360
  361 NFTTQELSSN PPLATILIPP HARIQAAASP PANATAASDT NAGDRGQTNN AASASASNST 420
  421

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: GSK3B_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: