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Any process that terminates the activity of the active enzyme MAP kinase. Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. Any process that modulates the frequency, rate or extent of protein kinase activity. Any process that modulates the frequency, rate or extent of a signaling pathway. Any process that modulates the frequency, rate or extent of MAP kinase activity. Any process that stops, prevents or reduces the frequency, rate or extent of MAP kinase activity. Any process that stops, prevents or reduces the frequency, rate or extent of protein kinase activity. Any process that modulates the frequency, rate or extent of signal transduction. Any process that stops, prevents or reduces the frequency, rate or extent of JUN kinase activity.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of MAP kinase activity
Acc: GO:0043407
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of MAP kinase activity.
Synonyms:
  • down regulation of MAPK activity
  • inhibition of MAPK activity
  • negative regulation of mitogen activated protein kinase activity
  • downregulation of MAPK activity
  • negative regulation of mitogen-activated protein kinase activity
  • down-regulation of MAPK activity
Proteins in PDR annotated with:
   This term: 46 [Search]
   Term or descendants: 89 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043407 - negative regulation of MAP kinase activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle