General Information: |
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Name(s) found: |
GSK3B_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 420 amino acids |
Gene Ontology: |
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Cellular Component: |
neuronal cell body
[UNKNOWN]
protein complex [IDA] membrane-bounded organelle [UNKNOWN] growth cone [UNKNOWN] beta-catenin destruction complex [UNKNOWN] nucleus [UNKNOWN][IDA] soluble fraction [IDA] cytoplasm [UNKNOWN][IDA][TAS] dendritic shaft [UNKNOWN] dendritic spine [IDA] membrane raft [IDA] cytosol [UNKNOWN][IDA] Axin-APC-beta-catenin-GSK3B complex [UNKNOWN] |
Biological Process: |
negative regulation of MAP kinase activity
[IMP]
fat cell differentiation [UNKNOWN] protein amino acid phosphorylation [UNKNOWN][IDA] ER overload response [UNKNOWN] re-entry into mitotic cell cycle [UNKNOWN] negative regulation of dendrite morphogenesis [IMP] anti-apoptosis [UNKNOWN] negative regulation of transcription, DNA-dependent [IDA] induction of apoptosis [IDA][TAS] regulation of neuronal synaptic plasticity [IMP] Wnt receptor signaling pathway [UNKNOWN][IEA] cell migration [UNKNOWN] positive regulation of protein complex assembly [UNKNOWN] positive regulation of peptidyl-serine phosphorylation [UNKNOWN] positive regulation of protein export from nucleus [UNKNOWN] establishment or maintenance of cell polarity [IDA] protein export from nucleus [UNKNOWN] response to stress [UNKNOWN] organ morphogenesis [UNKNOWN] glycogen metabolic process [UNKNOWN] intracellular signaling pathway [UNKNOWN] response to drug [IEP] negative regulation of apoptosis [UNKNOWN] response to lithium ion [IEP] establishment of cell polarity [IDA] positive regulation of peptidyl-threonine phosphorylation [UNKNOWN] peptidyl-serine phosphorylation [UNKNOWN] |
Molecular Function: |
protein kinase binding
[IPI]
ionotropic glutamate receptor binding [IPI] protein kinase activity [UNKNOWN] beta-catenin binding [UNKNOWN] protein serine/threonine kinase activity [UNKNOWN][IDA] glycogen synthase kinase 3 activity [UNKNOWN][IDA][TAS] nucleotide binding [IEA] tau-protein kinase activity [UNKNOWN][IDA] NF-kappaB binding [UNKNOWN] ATP binding [IDA] p53 binding [UNKNOWN] protein binding [UNKNOWN][IDA][IPI] tau protein binding [IDA] protein kinase A catalytic subunit binding [UNKNOWN] transferase activity [IEA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MSGRPRTTSF AESCKPVQQP SAFGSMKVSR DKDGSKVTTV VATPGQGPDR PQEVSYTDTK 60 61 VIGNGSFGVV YQAKLCDSGE LVAIKKVLQD KRFKNRELQI MRKLDHCNIV RLRYFFYSSG 120 121 EKKDEVYLNL VLDYVPETVY RVARHYSRAK QTLPVIYVKL YMYQLFRSLA YIHSFGICHR 180 181 DIKPQNLLLD PDTAVLKLCD FGSAKQLVRG EPNVSYICSR YYRAPELIFG ATDYTSSIDM 240 241 WSAGCVLAEL LLGQPIFPGD SGVDQLVEII KVLGTPTREQ IREMNPNYTE FKFPQIKAHP 300 301 WTKVFRPRTP PEAIALCSRL LEYTPTARLT PLEACAHSFF DELRDPNVKL PNGRDTPALF 360 361 NFTTQELSSN PPLATILIPP HARIQAAASP PANATAASDT NAGDRGQTNN AASASASNST 420 421 |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.97 |
Source: Reynolds et al. (2008)