Protein Overview: RRI1

General Information:
Name(s) found:	RRI1 / YDL216C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|93117369\|ref\|NP_010065.2\| Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signali [NCBI NR] gi\|239938615\|sp\|Q12468.2\|CSN5_YEAST RecName: Full=COP9 signalosome complex subunit 5 [NCBI NR] COP9 signalosome complex subunit 5 OS=Saccharomyces cerevisiae GN=RRI1 PE=1 SV=2 [Swiss-Prot] Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling [SGD] RRI1 SGDID:S000002375, Chr IV from 70320-68998, reverse complement, Verified ORF, "Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopep [yeast-contam.fasta] Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling; Rri1p [Saccharomyces cere [nr-271106-contam.fasta] RRI1 SGDID:S000002375, Chr IV from 70320-68998, reverse complement, Verified ORF, "Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling" [yeast-bovrabprots.fasta] [chemostatdb.fasta] COP9 signalosome complex subunit 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RRI1 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] RRI1 SGDID:S000002375, Chr IV from 70319-68997, Genome Release 64-1-1, reverse complement, Verified ORF, "Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling" [yeast-030211-contam.fasta] RRI1 SGDID:S000002375, Chr IV from 70319-68997, Genome Release 64-2-1, reverse complement, Verified ORF, "Catalytic subunit of the COP9 signalosome (CSN) complex; acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling" [20141208_orf_trans.fasta] YDL216C SGDID:S000002375, Chr IV from 70319-68997, Genome Release 64-1-1, reverse complement, Verified ORF, "Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	440 amino acids
Gene Ontology:
Cellular Component:	signalosome [IDA][TAS]
Biological Process:	protein deneddylation [IMP ] adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion [IMP]
Molecular Function:	metalloendopeptidase activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSNKTVKE LRQLLKERYT VEDELTESIA LSSMRFKPSQ EPEFHALSQS SLLKTKLKQQ  60
   61 SSTDIPSYTH VLISKLSCEK ITHYAVRGGN IEIMGILMGF TLKDNIVVMD CFNLPVVGTE 120
  121 TRVNAQLESY EYMVQYIDEM YNHNDGGDGR DYKGAKLNVV GWFHSHPGYD CWLSNIDIQT 180
  181 QDLNQRFQDP YVAIVVDPLK SLEDKILRMG AFRTIESKSD DNSATSYYEL ETIIFDSELN 240
  241 RALFETKLNL HCVIEDDESE QISLNRLIDS MKQYSYLMDS KNVRTRIKLA TTSERVSNEN 300
  301 KKNIDYQNRS TRSQFCLNTQ RGDSTETSSF GSMFSGDNTS DVDMEDRNLT EFDSTDTSLC 360
  361 INGEPSIHVN RVERSSRSTD NFHNSKKRMN SNQERCHDEG NDMLQRNVLE TDYARAKNRI 420
  421 LASKIKQYER LRFYKDTFTL

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		CSI1 CSN9 PCI8 RPN5 RRI1 RRI2
View Details	Krogan NJ, et al. (2006)		CSI1 CSN9 ERV46 FPR2 HUL5 IQG1 MOT1 MPT5 NAS6 NMD3 NPT1 PCI8 PEP1 PST1 PUS9 RPN1 RPN10 RPN11 RPN12 RPN13 RPN14 RPN2 RPN5 RPN6 RPN7 RPN8 RPN9 RPT1 RPT2 RPT3 RPT4 RPT5 RPT6 RRI1 RRI2 SEC18 SEM1 SKP1 SPG5 SPO77 SQT1 SWA2 TCB2 TIP41 TOD6 TOR2 TSR4 UBP6 YEN1 YKL027W YMR258C YNL022C YPR003C YPT52
View Details	Gavin AC, et al. (2006)		CSI1 CSN9 PCI8 RRI1 RRI2
View Details	Gavin AC, et al. (2002)		CSI1 CSN9 PCI8 RPN5 RRI1 RRI2