Protein Overview: CAF4

General Information:
Name(s) found:	CAF4 / YKR036C [SGD]
Description(s) found: Found 8 descriptions. SHOW ALL	WD40 repeat-containing protein associated with the CCR4-NOT complex, interacts in a Ccr4p-dependent manner with Ssn2p; also interacts with Fis1p, Mdv1p and Dnm1p and plays a role in mitochondrial fission [SGD]
Organism:	Saccharomyces cerevisiae
Length:	643 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA ] CCR4-NOT complex [IPI]
Biological Process:	regulation of transcription, DNA-dependent [IGI][IMP][IPI] mitochondrial fission [IMP][IPI]
Molecular Function:	protein binding [IPI][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSGDTRGES SLVAKPIEII LNKLPHAILA QQQFQKYITS PIYRYLSKLL LFREVAWPES  60
   61 TKDTQKGQVG IFSFQNNYAD SATTFRILAH LDEHGYPLPN GAAEKNLPSL FEGFKATVSI 120
  121 IQQRLLLDNV DGATNSDKEK YVQLPDINTG FVNKTYSRID LTHLLEDVET NVENLSINKT 180
  181 LEMDELTRLD SMINELESRK LKILERVKHI DSKSTNLEND VTLIKDRINF IEEYNLEADR 240
  241 EQSLRKQMEE ERSSEASSFT QNEEAISSLC DVESKDTRLK DFYKMPHEKS HDKNRQIISE 300
  301 TYSRNTTAFR MTIPHGEHGN SITALDFDTP WGTLCSSSYQ DRIVKVWDLN HGIQVGELPG 360
  361 HLATVNCMQI DKKNYNMLIT GSKDATLKLW DLNLSREIYL DHSPLKEKTE EIVTPCIHNF 420
  421 ELHKDEITAL SFDSEALVSG SRDKKIFHWD LTTGKCIQQL DLIFTPTHSD IKMPARSLNN 480
  481 GACLLGTEAP MIGALQCYNS ALATGTKDGI VRLWDLRVGK PVRLLEGHTD GITSLKFDSE 540
  541 KLVTGSMDNS VRIWDLRTSS ILDVIAYDLP VSSLDFDGKL ITVGANEGGV NVFNMERDEH 600
  601 WMTPEPPHSL DGDELSRRIA IVKYKDGFLI NGHNDGDINV WTL

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		CAF16 CAF4 CCR4 CDC36 CDC39 DBF2 DHH1 IBA57 MOB1 MOT2 NOT3 NOT5 POP2
View Details	Krogan NJ, et al. (2006)		CAF4 ECM27 ERG6 MTF1 PZF1
View Details	Ho Y, et al. (2002)		ATP3 CAF4 CCT2 CCT3 CCT5 CCT6 ENT2 OSH7 SRP54 TCP1 YBL029W

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	CAF4	Huh WK, et al. (2003)

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: CAF4

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: