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Protein Overview: MTF1

General Information:
Name(s) found: MTF1 / YMR228W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Mitochondrial RNA polymerase specificity factor with structural similarity to S-adenosylmethionine-dependent methyltransferases and functional similarity to bacterial sigma-factors, interacts with mitochondrial core polymerase Rpo41p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 341 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [TASLink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    Biological Process: transcription from mitochondrial promoter [TASLink to PubMed article]
    Molecular Function: transcription cofactor activity [IGILink to PubMed article][IMPLink to PubMed article][TASLink to PubMed article]
    S-adenosylmethionine-dependent methyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVPIPGIKD ISKLKFFYGF KYLWNPTVYN KIFDKLDLTK TYKHPEELKV LDLYPGVGIQ  60
   61 SAIFYNKYCP RQYSLLEKRS SLYKFLNAKF EGSPLQILKR DPYDWSTYSN LIDEERIFVP 120
  121 EVQSSDHIND KFLTVANVTG EGSEGLIMQW LSCIGNKNWL YRFGKVKMLL WMPSTTARKL 180
  181 LARPGMHSRS KCSVVREAFT DTKLIAISDA NELKGFDSQC IEEWDPILFS AAEIWPTKGK 240
  241 PIALVEMDPI DFDFDVDNWD YVTRHLMILK RTPLNTVMDS LGHGGQQYFN SRITDKDLLK 300
  301 KCPIDLTNDE FIYLTKLFME WPFKPDILMD FVDMYQTEHS G

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CAF4 ECM27 ERG6 MTF1 PZF1
    View Details Qiu et al. (2008) MTF1 RPO41

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..254] PSI-BLAST 10089.0 Transcription factor sc-mtTFB
    2 View Details [255..341] PSI-BLAST 10089.0 Transcription factor sc-mtTFB


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle