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Protein Overview: gi|26996622

General Information:
Name(s) found: gi|26996622 [NCBI NR]
Description(s) found:
Found 4 descriptions.
SHOW ALL
  • gi|26996622|gb|AAH41114.1| RHOT1 protein [Homo sapiens] [NCBI NR]
    • Organism: Homo sapiens
    Length: 675 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRSWRCPGSL AGKQLRGRRG GPRRPKRLAG GAVGWVLLVR GVHSVRAGGG RPPRAADMKK  60
   61 DVRILLVGEP RVGKTSLIMS LVSEEFPEEV PPRAEEITIP ADVTPERVPT HIVDYSEAEQ 120
  121 SDEQLHQEIS QANVICIVYA VNNKHSIDKV TSRWIPLINE RTDKDSRLPL ILVGNKSDLV 180
  181 EYSSMETILP IMNQYTEIET CVECSAKNLK NISELFYYAQ KAVLHPTGPL YCPEEKEMKP 240
  241 ACIKALTRIF KISDQDNDGT LNDAELNFFQ RICFNTPLAP QALEDVKNVV RKHISDGVAD 300
  301 SGLTLKGFLF LHTLFIQRGR HETTWTVLRR FGYDDDLDLT PEYLFPLLKI PPDCTTELNH 360
  361 HAYLFLQSTF DKHDLDRDCA LSPDELKDLF KVFPYIPWGP DVNNTVCTNE RGWITYQGFL 420
  421 SQWTLTTYLD VQRCLEYLGY LGYSILTEQE SQASAVTVTR DKKIDLQKKQ TQRNVFRCNV 480
  481 IGVKNCGKSG VLQALLGRNL MRQKKIREDH KSYYAINTVY VYGQEKYLLL HDISESEFLT 540
  541 EAEIICDVVC LVYDVSNPKS FEYCARIFKQ HFMDSRIPCL IVAAKSDLHE VKQEYSISPT 600
  601 DFCRKHKMPP PQAFTCNTAD APSKDIFVKL TTMAMYPHVT QADLKSSTFW LRASFGATVF 660
  661 AVLGFAMYKA LLKQR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..255] PSI-BLAST 40.09691 Structure of doubly prenylated Ypt1:GDI complex
    2 View Details [256..332] MSA 2.191989 View MSA. Confident ab initio structure predictions are available.
    3 View Details [333..675] PSI-BLAST 34.39794 Structure of the GTP-binding protein TrmE from Thermotoga maritima

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • microtubule motor activity
    		•  5.18272645402624 bayes_pls_golite062009
  • microfilament motor activity
    		•  3.88223640822153 bayes_pls_golite062009
  • motor activity
    		•  3.73454248797903 bayes_pls_golite062009
  • transporter activity
    		•  3.10463051760206 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.95886887664984 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.89122312915795 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.81593838944939 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.79724985811732 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.79347973548337 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  2.61775212528604 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  2.61467977505707 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  2.57552435627908 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  2.57107347424517 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  2.57054427875021 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.50494515048649 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  2.48415758556089 bayes_pls_golite062009
  • ATPase activity
    		•  2.44176688200537 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.43862163407966 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.4101693596493 bayes_pls_golite062009
  • actin binding
    		•  2.2973522188675 bayes_pls_golite062009
  • tubulin binding
    		•  1.92557767696163 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.91091452720653 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  1.89320355239381 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  1.88721318481223 bayes_pls_golite062009
  • GTP binding
    		•  1.87900088157196 bayes_pls_golite062009
  • microtubule binding
    		•  1.84561785126784 bayes_pls_golite062009
  • plus-end-directed microtubule motor activity
    		•  1.8063519626342 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.56325751172863 bayes_pls_golite062009
  • hydrolase activity
    		•  1.40217504818333 bayes_pls_golite062009
  • actin filament binding
    		•  1.28204719195916 bayes_pls_golite062009
  • GTPase activity
    		•  1.23010905798386 bayes_pls_golite062009
  • signal transducer activity
    		•  1.13474466330485 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.13474466330485 bayes_pls_golite062009
  • protein transporter activity
    		•  1.05248757342537 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.977237423302079 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • helicase activity
    		•  0.86140695609019 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.777787753097919 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.762584163889896 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.75383985982414 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.557919489256916 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.49000746592281 bayes_pls_golite062009
  • DNA binding
    		•  0.479412476059825 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • receptor activity
    		•  0.381142123108547 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.355770151889237 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.34746349346164 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.312171320541728 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  0.30832907234141 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  0.29532978396745 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven protein transmembrane transporter activity
    		•  0.28297830193871 bayes_pls_golite062009
  • macromolecule transmembrane transporter activity
    		•  0.28297830193871 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.25143870859482 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.25143870859482 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  0.213018989352421 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.123304946374679 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.0775601177068852 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0111338193708552 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • microtubule motor activity
    		•  5.18272645402624 bayes_pls_golite062009
  • microfilament motor activity
    		•  3.88223640822153 bayes_pls_golite062009
  • motor activity
    		•  3.73454248797903 bayes_pls_golite062009
  • transporter activity
    		•  3.10463051760206 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.95886887664984 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.89122312915795 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.81593838944939 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.79724985811732 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.79347973548337 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  2.61775212528604 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  2.61467977505707 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  2.57552435627908 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  2.57107347424517 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  2.57054427875021 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.50494515048649 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  2.48415758556089 bayes_pls_golite062009
  • ATPase activity
    		•  2.44176688200537 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.43862163407966 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.4101693596493 bayes_pls_golite062009
  • actin binding
    		•  2.2973522188675 bayes_pls_golite062009
  • tubulin binding
    		•  1.92557767696163 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.91091452720653 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  1.89320355239381 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  1.88721318481223 bayes_pls_golite062009
  • GTP binding
    		•  1.87900088157196 bayes_pls_golite062009
  • microtubule binding
    		•  1.84561785126784 bayes_pls_golite062009
  • plus-end-directed microtubule motor activity
    		•  1.8063519626342 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.56325751172863 bayes_pls_golite062009
  • hydrolase activity
    		•  1.40217504818333 bayes_pls_golite062009
  • actin filament binding
    		•  1.28204719195916 bayes_pls_golite062009
  • GTPase activity
    		•  1.23010905798386 bayes_pls_golite062009
  • signal transducer activity
    		•  1.13474466330485 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.13474466330485 bayes_pls_golite062009
  • protein transporter activity
    		•  1.05248757342537 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.977237423302079 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • helicase activity
    		•  0.86140695609019 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.777787753097919 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.762584163889896 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.75383985982414 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.557919489256916 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.49000746592281 bayes_pls_golite062009
  • DNA binding
    		•  0.479412476059825 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • receptor activity
    		•  0.381142123108547 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.355770151889237 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.34746349346164 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.312171320541728 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  0.30832907234141 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  0.29532978396745 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven protein transmembrane transporter activity
    		•  0.28297830193871 bayes_pls_golite062009
  • macromolecule transmembrane transporter activity
    		•  0.28297830193871 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.25143870859482 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.25143870859482 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  0.213018989352421 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.123304946374679 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.0775601177068852 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0111338193708552 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle