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Protein Overview: gi|20140914, gi|...

General Information:
Name(s) found: gi|5689463 [NCBI NR]
gi|20140914 [NCBI NR]
Description(s) found:
Found 11 descriptions.
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  • gi|5689463|dbj|BAA83015.1| KIAA1063 protein [Homo sapiens] [NCBI NR]
  • sp|Q9UPT9|UB22_HUMAN Ubiquitin carboxyl-terminal hydrolase 22 (Ubiquitin thiolesterase 22) (Ubiquitin-specific processing protease 22) (Deubiquitinating enzyme 22) [NCBI NR]
    • Organism: Homo sapiens
    Length: 593 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAAARGRCLP CSLPSAIAQP HLCPASALCS RRPGLGQPGQ PPSSPHAALA SSSPPSPPPP  60
   61 ARGRALPPMV SRPEPEGEAM DAELAVAPPG CSHLGSFKVD NWKQNLRAIY QCFVWSGTAE 120
  121 ARKRKAKSCI CHVCGVHLNR LHSCLYCVFF GCFTKKHIHE HAKAKRHNLA IDLMYGGIYC 180
  181 FLCQDYIYDK DMEIIAKEEQ RKAWKMQGVG EKFSTWEPTK RELELLKHNP KRRKITSNCT 240
  241 IGLRGLINLG NTCFMNCIVQ ALTHTPLLRD FFLSDRHRCE MQSPSSCLVC EMSSLFQEFY 300
  301 SGHRSPHIPY KLLHLVWTHA RHLAGYEQQD AHEFLIAALD VLHRHCKGDD NGKKANNPNH 360
  361 CNCIIDQIFT GGLQSDVTCQ VCHGVSTTID PFWDISLDLP GSSTPFWPLS PGSEGNVVNG 420
  421 ESHVSGTTTL TDCLRRFTRP EHLGSSAKIK CSGCHSYQES TKQLTMKKLP IVACFHLKRF 480
  481 EHSAKLRRKI TTYVSFPLEL DMTPFMASSK ESRMNGQYQQ PTDSLNNDNK YSLFAVVNHQ 540
  541 GTLESGHYTS FIRQHKDQWF KCDDAIITKA SIKDVLDSEG YLLFYHKQFL EYE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..77] deduced N/A No confident structure predictions are available.
    2 View Details [78..217] PSI-BLAST 11.69897 No description for 2g43A was found.
    3 View Details [218..593] PSI-BLAST 62.045757 No description for 2ibiA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  5.97121728620188 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  5.78935175140238 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  4.75377804653841 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  3.4560986989594 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  3.40436079043913 bayes_pls_golite062009
  • binding
    		•  2.78710909602478 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  2.7771990270637 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.72498741013971 bayes_pls_golite062009
  • protein binding
    		•  2.64803540957326 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  2.57382484274962 bayes_pls_golite062009
  • ligase activity
    		•  2.30828657077565 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  2.27286633653932 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  2.11206038007886 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.01888784395048 bayes_pls_golite062009
  • DNA binding
    		•  2.00904221080834 bayes_pls_golite062009
  • transcription activator activity
    		•  1.45530270292081 bayes_pls_golite062009
  • transcription factor activity
    		•  1.22579085356684 bayes_pls_golite062009
  • transcription factor binding
    		•  1.11842175076436 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  1.04342463991885 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.926364718530146 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.90321253993065 bayes_pls_golite062009
  • hydrolase activity
    		•  0.52386813728704 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.350170315296021 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.255669498391574 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.233838999434784 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009
    3
    Term Confidence Notes
  • cysteine-type peptidase activity
    		•  6.54685807643041 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  6.39247995905454 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  5.98024578817189 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  5.91394445088241 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  5.72435045666828 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  5.72435045666828 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  5.54975627252977 bayes_pls_golite062009
  • acetyltransferase activity
    		•  4.98167814132869 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  4.63274143638005 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  4.1832081096766 bayes_pls_golite062009
  • acyltransferase activity
    		•  4.01951010659818 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.96057134514922 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  2.96735553959103 bayes_pls_golite062009
  • peptidase activity
    		•  2.8192612691912 bayes_pls_golite062009
  • hydrolase activity
    		•  2.66167923792227 bayes_pls_golite062009
  • SUMO-specific protease activity
    		•  2.65263825059319 bayes_pls_golite062009
  • endopeptidase activity
    		•  2.56654871607946 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.55227247835105 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.13534310479552 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.13397229861051 bayes_pls_golite062009
  • cysteine-type endopeptidase activity
    		•  1.95802900199539 bayes_pls_golite062009
  • DNA binding
    		•  1.95013248594294 bayes_pls_golite062009
  • protein binding
    		•  1.92445772322782 bayes_pls_golite062009
  • binding
    		•  1.92046698500094 bayes_pls_golite062009
  • tubulin binding
    		•  1.85112496470487 bayes_pls_golite062009
  • microtubule binding
    		•  1.82320858139311 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.74961503597682 bayes_pls_golite062009
  • transcription activator activity
    		•  1.24058404587058 bayes_pls_golite062009
  • transcription factor activity
    		•  1.20242512567523 bayes_pls_golite062009
  • catalytic activity
    		•  1.05972260874031 bayes_pls_golite062009
  • NEDD8-specific protease activity
    		•  0.687958315289315 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.467924587720185 bayes_pls_golite062009
  • structural molecule activity
    		•  0.297752217869698 bayes_pls_golite062009
  • signal transducer activity
    		•  0.26868506520228 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.26868506520228 bayes_pls_golite062009
  • calcium-dependent cysteine-type endopeptidase activity
    		•  0.196538841514154 bayes_pls_golite062009
  • ligase activity
    		•  0.109097233197606 bayes_pls_golite062009
  • transferase activity
    		•  0.0852393573521809 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle