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Protein Overview: MSS18

General Information:
Name(s) found: MSS18 / YPR134W [SGD]
Description(s) found:
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  • pir||S00553 MSS18 protein - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|6325392|ref|NP_015460.1| Nuclear encoded protein needed for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions; Mss18p [Sacc [NCBI NR]
  • gi|4004|emb|CAA30490.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|127360|sp|P08593.1|MSS18_YEAST RecName: Full=Protein MSS18 [NCBI NR]
  • gi|1066484|gb|AAB68275.1| Mss18p: Mitochondrial splicing protein (Swiss Prot. accession number P05893). [Saccharomyces cerevisiae] [NCBI NR]
  • Protein MSS18 OS=Saccharomyces cerevisiae GN=MSS18 PE=1 SV=1 [Swiss-Prot]
  • (P08593) MSS18 protein [Swiss-Prot]
  • MSS18 Splicing protein [mips]
  • Nuclear encoded protein needed for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions [SGD]
  • Chr XVI from 798045-798851 [hmr_yeast5_DM3-1_pombe.fasta]
  • Chr XVI from 798046-798852 [yeastorf3.fasta]
  • MSS18, Chr XVI from 798046-798852 [yeast_orfs2]
  • MSS18 SGDID:S0006338, Chr XVI from 798045-798851, Verified ORF [yeastflysequest.fasta]
  • MSS18 SGDID:S0006338, Chr XVI from 798047-798853, Verified ORF [10112005cervSGD.fasta]
  • Mss18p [Saccharomyces cerevisiae]gi|1066484|gb|AAB68275.1| Mss18p: Mitochondrial splicing protein (Swiss Prot. accession number P05893). [Saccharomyces cerevisiae]gi|4004|emb|CAA30490.1| unnamed protein product [Saccharomyces cerevisiae]gi|127360|sp|P0 [nrdb_11152004_Chlamydomonas]
  • MSS18 SGDID:S000006338, Chr XVI from 798047-798853, Verified ORF, "Nuclear encoded protein needed for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain sugg [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • Mss18p: Mitochondrial splicing protein (Swiss Prot. accession number P05893). [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Nuclear encoded protein needed for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions; Mss18p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Protein MSS18 [nr-271106-contam.fasta]
  • MSS18 SGDID:S000006338, Chr XVI from 798047-798853, Verified ORF, "Nuclear encoded protein needed for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • Protein MSS18 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSS18 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • MSS18 SGDID:S000006338, Chr XVI from 798051-798857, Genome Release 64-1-1, Verified ORF, "Nuclear encoded protein needed for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions" [yeast-030211-contam.fasta]
  • MSS18 SGDID:S000006338, Chr XVI from 798051-798857, Genome Release 64-2-1, Verified ORF, "Nuclear encoded protein needed for splicing of mitochondrial intron; required for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions" [20141208_orf_trans.fasta]
  • YPR134W SGDID:S000006338, Chr XVI from 798051-798857, Genome Release 64-1-1, Verified ORF, "Nuclear encoded protein needed for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 268 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [ICLink to PubMed article][IDALink to PubMed articleLink to PubMed article]
    Biological Process: Group I intron splicing [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLPEVNFLR KNCILVELKL FYQTVYPPKE LYWNNRITAE LSTFSNIKYA RPTFAVNNGT  60
   61 FQRTRPKLDL VLASSDIRKL ATVLFNLKAL IMNTKGEEPT LTTMTSVQTN EEKNDNLEQK 120
  121 YSSLLDRWNG KVEVHDSPFL QLQRDSNLLF AERPVRYVST TEGEGVDISS EEFFRLEEEQ 180
  181 CRRNYDVLVD EHSTPSVGMK DGQYGPNIIH FEPSLYHTYS SLPMSMKFWL NGLEDDETTM 240
  241 MNIDEKSAEN LDILLHGFKG FSNKRVKG

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) BI4 CBP6 MRS1 MRS2 MRS3 MRS4 MSS1 MSS116 MSS18 MTF2 NAM2 PET54 TIM10
    View Details Krogan NJ, et al. (2006) CWC22 MSS18 PRP19 PRP46 YLR132C
    View Details Qiu et al. (2008) BI3 BI4 MSS18

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PPM1 MSS18 1 Unpublished Fields Lab Data
    View Screen RAD54 MSS18 1 Unpublished Fields Lab Data
    View Screen CUS1 MSS18 1 Unpublished Fields Lab Data
    View Screen PSE1 MSS18 1 Unpublished Fields Lab Data
    View Screen SAS3 MSS18 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data MSS18 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..268] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle