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Protein Overview: CSR2

General Information:
Name(s) found: CSR2 / YPR030W [SGD]
Description(s) found:
Found 27 descriptions.
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  • Nuclear protein proposed to regulate utilization of nonfermentable carbon sources and endocytosis of plasma membrane proteins; overproduction suppresses chs5 spa2 lethality at high temp; ubiquitinated by Rsp5p, deubiquitinated by Ubp2p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1121 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: cellular cell wall organization [IGILink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSTVPIAIA SNGNKRDVVQ NVSAGDEGDI LQRLARNREM ISTSLSPQKS SGFSGRRRSS  60
   61 SVRDALSSFF GTGNSPTSSM DDYSNLMNRN YSTASTAMCR GNSFPSDVGT KAYNITGSYQ 120
  121 PDRHRNSVPY TTIDQLHTRQ DTGLRRESDP VAAKQISSNN DIVRSFITHH ASNSTMFINR 180
  181 VLSDYLADRG FIKQTPLYNK KSVLEISIAT SAESVFLPTT KSDETEYLSL IHGSLNQART 240
  241 QPVGSTNTAE SDFLPSCPTM DTLNENNDLS LFPLHTQRTS PSNTARTGNA MDTSNSDRAS 300
  301 PASNNNTTDA DSFVASGNNN PMNNNNSPAR NRHPNSHSRS LPNAWNSQMP SFSFALIFSL 360
  361 NKSTTLSDIK VELTSNVRVV WFNGLPPTKN VNEECYNIGS LDWTLNADNF NLFIPQGAKS 420
  421 PLDIVENHSN NRKLKVLQKL SMRKRRSFSN KAVLRENILN NLNASNSTNK LNAGVYVFTI 480
  481 PIVLASRIPE SLYYPSARVS YSLRLATKLK DEHTQLVASR PRSSSISSPQ KLRSYSCSDS 540
  541 YEYSQIDDTI EGETYNNDKN STGKIAFPSS WLKSAKGRLK RNNSNGRSDN NGASSSGLAM 600
  601 QHDSEDTINL QYPLNLVRTP PEISVTTANK PLYINKVWEN CLSYEISFAQ KYVPLNGEIP 660
  661 ITIKVAPLVK SLSVKRIRVS CREKISYRSK DYQYDFDQLD PLASDPCNPY HMRYLVRKKK 720
  721 DRSLPLFEVA SKCTSGPSIR EEVVTNTVDD NLLAYTSSKE NNKDIPFSES FTVKTKLKFP 780
  781 KYCEVDATKA ASLPPYGIDL FDPIKDPTQS ENTSNNGNVL GFLVGRPNRA SKTVHKIPQD 840
  841 KNHNEVNDTN GNSNTSLQTS SNVPIQHYTR LNKPRRGLYL DSMHFKNIQC SHKLEIVLRV 900
  901 SKTDSGSSKI IRHYEVIVDT PIYLISDLCN TSNIDLPTYD MATTESSKVL PPTFEEATSV 960
  961 SASPRSSVSY YPDDISMQQL NLSRSTSLAN GYLSTLHPKT TAVSDSSNGA PIRDQQEQQA1020
 1021 RPLRTEDYAL QMGNENNAYS NMDGLLSQDI FEQETAATLF KRDIVTMNFN NNIFTPRYSP1080
 1081 RTFTNTDYNY NDNDNNDNDT EGPGPIIHPG PEPPRYDEIS S

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ADR1 BMH1 BMH2 BNR1 BOI2 CSR2 CYK3 GSY2 HYP2 KCS1 NTH1 REG1 SOK1 STU1 SVL3 WHI2 YFR017C YIL028W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen UBP6 CSR2 2 Unpublished Fields Lab Data
    View Screen SPT21 CSR2 1 Unpublished Fields Lab Data
    View Screen GIR2 CSR2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..268] deduced N/A No confident structure predictions are available.
    2 View Details [269..549] MSA 3.076954 View MSA. No confident structure predictions are available.
    3 View Details [550..791] PSI-BLAST 28.0 Arrestin
    4 View Details [792..1121] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.65544526722793 bayes_pls_golite062009
  • protein binding
    		•  1.50286160643298 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.24498703916422 bayes_pls_golite062009
  • actin binding
    		•  0.15943777627145 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle