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Protein Overview: GEP3

General Information:
Name(s) found: GEP3 / YOR205C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Protein of unknown function; null mutant is defective in respiration and interacts synthetically with prohibitin (phb1); the authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 556 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNLCHALRG VRQFSCSVIV KVKCASCSIK LQDQDPSKPG YYTKPKSLPD SKLNPDLQDL  60
   61 KYLLFSQDIQ LSKQATQNDP DLKTKRDLLL RVICKRCSNA LHHNNYNPEE FPESTLNDIL 120
  121 NYVPRGSNVM HIVPFVEFPL HLDPNVLKRN DLDTTLVLTK SDQVFKDKNA VSKKVPIFMK 180
  181 QFLKNTLRID SNKTFAISAL KNWNISMFYN YFKNYTYLLG NPNVGKSTLI NTLLQKYLGY 240
  241 KVKIDSTGKI NSPSEEVMQE AFTNPKNFFK IQAAGVSHIP NLTRSVQAYQ VGGKILFDLP 300
  301 GYSTSTSRLR LEELIDERWL QRLRKTDLFN RKHIKQKTYE SMKGTSQGGC YTVGGIFYLV 360
  361 PPKGSINQIV KYIPGPSKTF KNIEKGIDVF NSCNSSSGTH PLSRYCGIKS VICEKSQYKR 420
  421 YAIPPFIGSI EIVLKDIGYI LLRTTGRYEF KGLHEIWIPR GIQVGIREPL ENLIESGYQR 480
  481 YIETNGKESS CPRDRPIISS LYEMAPDEAD TLNAVKKSYL EKTEKDLSAR RFVDDDPYDL 540
  541 VQHLEKKKNP YWYYQW

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2002) BEM2 CCM1 ECM16 EHD3 FYV4 GEP3 HSC82 MRP1 MRP10 MRP13 MRP17 MRP21 MRP4 MRP51 MRPS16 MRPS17 MRPS18 MRPS28 MRPS5 MRPS8 MRPS9 NAM9 PAP2 PET123 PSD2 PUS7 RIX1 RSM10 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM7 TIF4631 UBP10 UTP20 UTP22

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SWI5 GEP3 1 Unpublished Fields Lab Data
    View Screen UBC7 GEP3 1 Unpublished Fields Lab Data
    View Screen CTF13 GEP3 1 Unpublished Fields Lab Data
    View Screen NAF1 GEP3 1 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data GEP3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..224] PSI-BLAST 10.0 GTPase Era, N-terminal domain; GTPase Era C-terminal domain
    2 View Details [225..556] MSA 2.311991 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle