YRC Public Data Repository - Protein Structure Prediction

Protein:	GEP3
Organism:	Saccharomyces cerevisiae
Length:	556 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GEP3.

Description	E-value	Query Range	Subject Range
GEP3 - Protein of unknown function; null mutant is defective in respiration and interacts synthetically wit... GEP3_YEAST - Genetic interactor of prohibitins 3, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 /...	0.0	[1..556]	[1..556]
gi\|134272647, gi... - gi\|139474400\|ref\|YP_001129116.1\| GTP-binding protein YqeH [Streptococcus pyogenes str. Manfredo], gi... gi\|71902919, gi\|... - gi\|71902919\|ref\|YP_279722.1\| GTP-binding protein YqeH [Streptococcus pyogenes MGAS6180], gi\|71802014... gi\|19745428, gi\|... - gi\|19747540\|gb\|AAL97063.1\| conserved hypothetical protein [Streptococcus pyogenes MGAS8232], gi\|1974...	3.0E-68	[20..471]	[2..372]
gi\|28896548, gi\|... - gi\|28896548\|ref\|NP_802898.1\| GTP-binding protein YqeH [Streptococcus pyogenes SSI-1], gi\|28811802\|db... gi\|15674473, gi\|... - gi\|15674473\|ref\|NP_268647.1\| GTP-binding protein YqeH [Streptococcus pyogenes M1 GAS], gi\|13621572\|g... gi\|21909760, gi\|... - gi\|21909760\|ref\|NP_664028.1\| GTP-binding protein YqeH [Streptococcus pyogenes MGAS315], gi\|21903945\|... gi\|71910075, gi\|... - gi\|71910075\|ref\|YP_281625.1\| GTP-binding protein YqeH [Streptococcus pyogenes MGAS5005], gi\|71852857...	6.0E-68	[20..471]	[2..372]
gi\|224501569 - gi\|224501569\|ref\|ZP_03669876.1\| GTP-binding protein YqeH [Listeria monocytogenes FSL R2-561] gi\|25514388, gi\|... - pir\|\|AC1261 hypothetical protein lmo1491 [imported] - Listeria monocytogenes (strain EGD-e), gi\|1641... gi\|16803531 - gi\|16803531\|ref\|NP_465016.1\| GTP-binding protein YqeH [Listeria monocytogenes EGD-e] gi\|153196269, gi... - gi\|254829750\|ref\|ZP_05234405.1\| GTP-binding protein YqeH [Listeria monocytogenes 10403S], gi\|1531962...	2.0E-67	[18..471]	[1..366]
gi\|16800594 - gi\|16800594\|ref\|NP_470862.1\| GTP-binding protein YqeH [Listeria innocua Clip11262] gi\|16413999, gi\|... - pir\|\|AE1623 hypothetical protein homolog lin1526 [imported] - Listeria innocua (strain Clip11262), g...	3.0E-67	[18..471]	[1..366]
gi\|25402381 - pir\|\|E86652 GTP-binding protein [imported] - Lactococcus lactis subsp. lactis (strain IL1403) gi\|15672203, gi\|... - gi\|15672203\|ref\|NP_266377.1\| GTP-binding protein YqeH [Lactococcus lactis subsp. lactis Il1403], gi\|...	1.0E-66	[22..471]	[1..380]
gi\|25489806 - pir\|\|C83815 hypothetical protein BH1323 [imported] - Bacillus halodurans (strain C-125) gi\|15613886, gi\|... - gi\|15613886\|ref\|NP_242189.1\| GTP-binding protein YqeH [Bacillus halodurans C-125], gi\|10173939\|dbj\|B...	7.0E-66	[22..471]	[6..367]
gi\|21281233, gi\|... - gi\|4115915\|gb\|AAD03426.1\| contains similarity to Helix pomatia br-1 protein (GB: X96994) [Arabidopsi...	1.0E-65	[17..470]	[80..530]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	7.0E-65	[17..470]	[80..538]
gi\|221319738 - gi\|221319738\|ref\|ZP_03601032.1\| GTP-binding protein YqeH [Bacillus subtilis subsp. subtilis str. JH6... YQEH_BACSU - Uncharacterized protein yqeH OS=Bacillus subtilis GN=yqeH PE=1 SV=1 gi\|221314816 - gi\|221314816\|ref\|ZP_03596621.1\| GTP-binding protein YqeH [Bacillus subtilis subsp. subtilis str. NCI... YQEH_BACSU - Uncharacterized protein YqeH OS=Bacillus subtilis (strain 168) GN=yqeH PE=1 SV=1 gi\|221324016 - gi\|221324016\|ref\|ZP_03605310.1\| GTP-binding protein YqeH [Bacillus subtilis subsp. subtilis str. SMY...	3.0E-64	[20..471]	[2..366]

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Predicted Domain #1

Region A:
Residues: [1-224]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNLCHALRG VRQFSCSVIV KVKCASCSIK LQDQDPSKPG YYTKPKSLPD SKLNPDLQDL  60
   61 KYLLFSQDIQ LSKQATQNDP DLKTKRDLLL RVICKRCSNA LHHNNYNPEE FPESTLNDIL 120
  121 NYVPRGSNVM HIVPFVEFPL HLDPNVLKRN DLDTTLVLTK SDQVFKDKNA VSKKVPIFMK 180
  181 QFLKNTLRID SNKTFAISAL KNWNISMFYN YFKNYTYLLG NPNV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.0
Match:	1egaA_
Description:	GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [225-556]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKSTLINTLL QKYLGYKVKI DSTGKINSPS EEVMQEAFTN PKNFFKIQAA GVSHIPNLTR  60
   61 SVQAYQVGGK ILFDLPGYST STSRLRLEEL IDERWLQRLR KTDLFNRKHI KQKTYESMKG 120
  121 TSQGGCYTVG GIFYLVPPKG SINQIVKYIP GPSKTFKNIE KGIDVFNSCN SSSGTHPLSR 180
  181 YCGIKSVICE KSQYKRYAIP PFIGSIEIVL KDIGYILLRT TGRYEFKGLH EIWIPRGIQV 240
  241 GIREPLENLI ESGYQRYIET NGKESSCPRD RPIISSLYEM APDEADTLNA VKKSYLEKTE 300
  301 KDLSARRFVD DDPYDLVQHL EKKKNPYWYY QW

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits