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Protein Overview: RSB1

General Information:
Name(s) found: RSB1 / YOR049C [SGD]
Description(s) found:
Found 21 descriptions.
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  • Suppressor of sphingoid long chain base (LCB) sensitivity of an LCB-lyase mutation; putative integral membrane transporter or flippase that may transport LCBs from the cytoplasmic side toward the extracytoplasmic side of the membrane [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 354 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: fatty acid transport [IDALink to PubMed article]
    phospholipid translocation [IMPLink to PubMed article]
    Molecular Function: phospholipid-translocating ATPase activity [IDALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVPNLRFNIT MIVIWGILLT IHVVQLLMRQ YWFSIAFICT GILEVLGFIG RTWSHSNVAD  60
   61 MDAFLLNMIC LTIAPVFTMG GIYYQLAKLI EVYGHRFSLL PSPMAYSFIF ICSDIVSLVV 120
  121 QAVGGGLCGV AVTDGTSTTT GNHVFIAGLA IQVASMAIFL MLWFHFLFRI YISVRWEHIN 180
  181 SRPISLSLLK ISQTEVDYLY REKFHFLRLE PKRWVFHYFN LAITVAVLTI FTRCCYRLAE 240
  241 LVVGWDGYLI THEWYFIILD ALMMAIATVT LTIFHPGFAF KGRSTSIPIT PGHVDPETLP 300
  301 HTDDVEDILD TSDSKQFDIE KEEFQASMKY PISTFKQFMS KIANLFSSKK KAKL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ATG33 BUB1 CUL3 GUT1 ISM1 MEC3 MLC1 MYO2 MYO4 RGA1 RSB1 SAT4 SHE2 SHE3 SHE4 SRC1 SSH4 STT4 TOF2 TVP18 YDR186C YOL098C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..183] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [184..354] MSA 1.011991 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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