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Protein Overview: SAT4

General Information:
Name(s) found: SAT4 / YCR008W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; partially redundant with Hal5p; has similarity to Npr1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 603 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: G1/S transition of mitotic cell cycle [IGILink to PubMed article]
    cellular cation homeostasis [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: protein kinase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGMNDNNAA IPQQTPRKHA LSSKVMQLFR SGSRSSRQGK ASSNIQPPSN INTNVPSASK  60
   61 SAKFGLHTPT TATPRVVSNP SNTAGVSKPG MYMPEYYQSA SPSHSSSSAS LNNHIDINTS 120
  121 KSSSAASLTS SVSALSLSPT SAINISSKSL SPKFSHHSNS NTAITPAPTP TASNINNVNK 180
  181 ITNTSAPICG RFLVHKDGTH EHHLKNAKRQ EKLSTMIKNM VGASKLRGEA KSAVPDIIMD 240
  241 PKTTLKSNKN PPTLFAGFMK QVVDMDDKYP EGAPTSGALN CPERDIYRSD QKDSKNNTHN 300
  301 ITTTKKDRQC FAEKYGRCQE VLGKGAFGVV RICQKKNVSS QDGNKSEKLY AVKEFKRRTS 360
  361 ESAEKYSKRL TSEFCISSSL HHTNIVTTLD LFQDAKGEYC EVMEYCAGGD LFTLVVAAGK 420
  421 LEYMEADCFF KQLIRGVVYM HEMGVCHRDL KPENLLLTHD GVLKITDFGN SECFKMAWEK 480
  481 NIHLSGGVCG SSPYIAPEEY IKEEFDPRPV DIWACGVIYM AMRTGRQLWS SAEKDDPFYM 540
  541 NYLKGRKEKG GYEPIESLKR ARCRNVIYSM LDPVPYRRIN GKQILNSEWG REIKCCHNGR 600
  601 ALK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ATG33 BUB1 CUL3 GUT1 ISM1 MEC3 MLC1 MYO2 MYO4 RGA1 RSB1 SAT4 SHE2 SHE3 SHE4 SRC1 SSH4 STT4 TOF2 TVP18 YDR186C YOL098C
    View Details Ho Y, et al. (2002) PHO85 SAT4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ASF1 3829 - low filter Green EM, et al (2005)
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..226] ORFEUS 14.21 RBP1
    2 View Details [227..279] deduced N/A No confident structure predictions are available.
    3 View Details [280..372]
    [389..404]    		 PSI-BLAST 397.67837 Cell cycle checkpoint kinase chk1
    4 View Details [373..388]
    [405..414]
    [430..482]    		 PSI-BLAST 397.67837 Cell cycle checkpoint kinase chk1
    5 View Details [415..429]
    [483..603]    		 PSI-BLAST 397.67837 Cell cycle checkpoint kinase chk1


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle