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Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive some other reaction, for example ion transport across a membrane. Catalysis of the movement of phospholipids from one membrane face to the other (phospolipid 'flippase' activity), driven by the hydrolysis of ATP. Enables the directed movement of phospholipids into, out of, within or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester. Enables the directed movement of lipids into, out of, within or between cells. Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive the transport of a substance.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: phospholipid-translocating ATPase activity
Acc: GO:0004012
Aspect: Molecular Function
Desc: Catalysis of the movement of phospholipids from one membrane face to the other (phospolipid 'flippase' activity), driven by the hydrolysis of ATP.
Synonyms:
  • Mg(2+)-ATPase activity
  • magnesium-ATPase activity
  • phospholipid translocating ATPase activity
  • aminophospholipid-transporting ATPase
  • Mg2+-ATPase activity
  • flippase activity
  • GO:0008557
  • ATP phosphohydrolase (phospholipid-flipping)
  • phospholipid-transporting ATPase activity
Proteins in PDR annotated with:
   This term: 105 [Search]
   Term or descendants: 105 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004012 - phospholipid-translocating ATPase activity (interactive image map)

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