YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: SGT2

General Information:
Name(s) found: SGT2 / YOR007C [SGD]
Description(s) found:
Found 31 descriptions.
SHOW ALL
  • Glutamine-rich cytoplasmic protein of unknown function; contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions; has similarity to human SGT, which is a cochaperone that negatively regulates Hsp70 [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 346 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: response to heat [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASKEEIAA LIVNYFSSIV EKKEISEDGA DSLNVAMDCI SEAFGFEREA VSGILGKSEF  60
   61 KGQHLADILN SASRVPESNK KDDAENVEIN IPEDDAETKA KAEDLKMQGN KAMANKDYEL 120
  121 AINKYTEAIK VLPTNAIYYA NRAAAHSSLK EYDQAVKDAE SAISIDPSYF RGYSRLGFAK 180
  181 YAQGKPEEAL EAYKKVLDIE GDNATEAMKR DYESAKKKVE QSLNLEKTVP EQSRDADVDA 240
  241 SQGASAGGLP DLGSLLGGGL GGLMNNPQLM QAAQKMMSNP GAMQNIQKMM QDPSIRQMAE 300
  301 GFASGGGTPN LSDLMNNPAL RNMAGNLFGG AGAQSTDETP DNENKQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) SGT2 YBR137W
    View Details Krogan NJ, et al. (2006) GET4 MDY2 NIP100 SGT2 YBR137W YDR026C
    View Details Ho Y, et al. (2002) CBK1 ECM10 GAL7 PRB1 SGT2 SSD1 UBP15

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample zds1 from august 2005 McCusker D, et al (2007)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PEX22 SGT2 2 Unpublished Fields Lab Data
    View Screen SGT2 YHL018W 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SGT2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..61] deduced N/A No confident structure predictions are available.
    2 View Details [62..291] PSI-BLAST 173.9691 Protein phosphatase 5
    3 View Details [292..346] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.12690485191789 bayes_pls_golite062009
  • protein binding
    		•  1.65083457326273 bayes_pls_golite062009
  • heat shock protein binding
    		•  1.35268080101836 bayes_pls_golite062009
  • unfolded protein binding
    		•  1.03065657981002 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.41706917101675 bayes_pls_golite062009
  • hydrolase activity
    		•  0.252678932946087 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.194719472400022 bayes_pls_golite062009
  • DNA binding
    		•  0.17736976899009 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle