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Protein Overview: AVO2

General Information:
Name(s) found: AVO2 / YMR068W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Component of a complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 426 amino acids

    Gene Ontology:
    Cellular Component: TORC2 complex [IPILink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: fungal-type cell wall organization [IPILink to PubMed article]
    regulation of cell growth [IPILink to PubMed article]
    establishment or maintenance of actin cytoskeleton polarity [IPILink to PubMed article]
    Molecular Function: molecular_function [NDLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKEPSVRLR EAIIEGNLLI VKRLLRRNPD LLTNIDSENG WSSLHYASYH GRYLICVYLI  60
   61 QLGHDKHELI KTFKGNTCVH LALMKGHEQT LHLLLQQFPR FINHRGENGR APIHIACMND 120
  121 YYQCLSLLIG VGADLWVMDT NGDTPLHVCL EYGSISCMKM LLNEGEVSLD DNVRDKGNWK 180
  181 PIDVAQTFEV GNIYSKVLKE VKKKGPPLGA GKKPSSFRTP ILNAKATFED GPSPVLSMNS 240
  241 PYSLYSNNSP LPVLPRRIST HTTSGNGGNR RSSITNPVFN PRKPTLSTDS FSSSSNSSSR 300
  301 LRVNSINVKT PVGVSPKKEL VSESVRHSAT PTSPHNNIAL INRYLLPNKS NDNVRGDSQT 360
  361 ATINDDGGGG NGGDATIGMG LRKDPDDENE NKYKIKVNNG EPRRRVSLLN IPISKLRNSN 420
  421 NTRAED

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) AVO2 PMU1 YER064C YGL039W YTA12
    View Details Qiu et al. (2008) AVO2 BIT61 LST8 SLM1 SLM2 TSC11

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run TOR2 No Comments Reinke A, et al. (2004)
    View Run LST8 No Comments Reinke A, et al. (2004)
    View Run TOR2 No Comments Reinke A, et al. (2004)
    View Run MLP2 #34 Asynchronous SPB prep Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..103] PSI-BLAST 91.69897 bcl-3
    2 View Details [104..229] PSI-BLAST 91.69897 bcl-3
    3 View Details [230..296] PSI-BLAST 15.154902 Swi6 ankyrin-repeat fragment
    4 View Details [297..426] MSA 6.272996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.96927469603571 bayes_pls_golite062009
  • protein binding
    		•  1.64872738860757 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.918965541481332 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.130000994167231 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle