Protein Overview: YLR243W

General Information:
Name(s) found:	YLR243W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|74644965\|sp\|Q06543.1\|FET5X_YEAST RecName: Full=Transcription factor YLR243W; AltName: Full=Factor of eukaryotic transcription 5 [NCBI NR] gi\|662338\|gb\|AAB67394.1\| Ylr243wp [Saccharomyces cerevisiae] [NCBI NR] gi\|6323272\|ref\|NP_013344.1\| Putative protein of unknown function; YLR243W is an essential gene; Ylr243wp [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S59389 probable membrane protein YLR243w - yeast (Saccharomyces cerevisiae) [NCBI NR] GPN-loop GTPase 3 homolog YLR243W OS=Saccharomyces cerevisiae GN=YLR243W PE=1 SV=1 [Swiss-Prot] Transcription factor YLR243W OS=Saccharomyces cerevisiae GN=YLR243W PE=1 SV=1 [Swiss-Prot] Protein required for cell viability [mips] Putative protein of unknown function; YLR243W is an essential gene [SGD] YLR243W, Chr XII from 624203-625021 [yeast_orfs2] Chr XII from 624203-625021 [yeastorf3.fasta] >Q06543 (Q06543) Similar to C. ELEGANS hypothetical protein C34E10.2 [4932.FASTACCERV.txt] YLR243W SGDID:S0004233, Chr XII from 624205-625023, Uncharacterized ORF [yeastflysequest.fasta] Protein required for cell viability [Saccharomyces cerevisiae]gi\|662338\|gb\|AAB67394.1\| Ylr243wp [Saccharomyces cerevisiae]gi\|1363742\|pir\|\|S59389 probable membrane protein YLR243w - yeast (Saccharomyces cerevisiae) [nrdb_11152004_Chlamydomonas] (Q06543) Ylr243wp [cerv4932.FASTAC] YLR243W SGDID:S000004233, Chr XII from 624205-625023, Uncharacterized ORF, "Protein required for cell viability" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YLR243W SGDID:S000004233, Chr XII from 624205-625023, Uncharacterized ORF, "Putative protein of unknown function; YLR243W is an essential gene" [yeast-contam.fasta] Ylr243wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Putative protein of unknown function; YLR243W is an essential gene; Ylr243wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] GPN-loop GTPase 3 homolog YLR243W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YLR243W PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] YLR243W SGDID:S000004233, Chr XII from 624203-625021, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; YLR243W is an essential gene" [yeast-030211-contam.fasta] GPN3 SGDID:S000004233, Chr XII from 624203-625021, Genome Release 64-2-1, Verified ORF, "Putative GTPase with a role in biogenesis of RNA pol II and polIII; may be involved in assembly of RNA polymerases II and III and in their transport into the nucleus; may have a role in sister chromatid cohesion; contains a Gly-Pro-Asn motif in the G domain; similar to Npa3p and Gpn2p" [20141208_orf_trans.fasta] TR398\|c0_g1_i1\|g.313 ORF TR398\|c0_g1_i1\|g.313 TR398\|c0_g1_i1\|m.313 type:complete len:273 (+) TR398\|c0_g1_i1:233-1051(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] asmbl_7383\|g.5292 ORF asmbl_7383\|g.5292 asmbl_7383\|m.5292 type:complete len:273 (+) asmbl_7383:106-924(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta] GPN-loop GTPase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GPN3 PE=1 SV=1 [uniprot_sprot.fasta.20160308] ID=asmbl_7362\|g.4536 ORF ID=asmbl_7362\|g.4536 ID=asmbl_7362\|m.4536 type:complete len:273 (+) ID=asmbl_7362:106-924(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	272 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	biological_process [ND]
Molecular Function:	signal sequence binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRVGVMVLG PAGAGKSTFC NSIISHMQTV GRRAHIVNLD PAAEATKYEF TIDIRDLISL  60
   61 DDVMEEMDLG PNGALIYCFE YLLKNLDWLD EEIGDFNDEY LIFDCPGQIE LYTHIPVLPN 120
  121 IVRHLTQQLN FNLCATYLLE APFVIDSSKF FSGALSAMSA MILLELPHIN VLSKLDLIKG 180
  181 DINKKKLKRF LNPDAMLLME TEGMNQASNP KFLRLNQCIA NLVDDFGMVQ FLPLESNNPD 240
  241 SIETILSYVD DITQWAEGQE QKEPNDQIDV EE

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Ho Y, et al. (2002)		DED1 GYP5 IDH1 ILV5 LYS12 MET18 PHO84 PRE10 RVS167 URA7 YLR243W

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	CEP3	sample cbf3 from feb 2005	Sandall S, et all (2006)
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
nucleoside-triphosphatase activity	2.95079405147356	bayes_pls_golite062009
pyrophosphatase activity	2.87427509025394	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.85499564954033	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.85178667290149	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.82708337557815	bayes_pls_golite062009
ion transmembrane transporter activity	2.73258998901465	bayes_pls_golite062009
transporter activity	2.58140740499725	bayes_pls_golite062009
cation transmembrane transporter activity	2.55141814687566	bayes_pls_golite062009
binding	2.44689197844883	bayes_pls_golite062009
transmembrane transporter activity	2.39695871109024	bayes_pls_golite062009
ATPase activity	2.39535714892224	bayes_pls_golite062009
ATPase activity, coupled	2.18396165590908	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	1.93945622138684	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	1.89410061122763	bayes_pls_golite062009
metal ion transmembrane transporter activity	1.63387464349089	bayes_pls_golite062009
hydrolase activity	1.57549510726226	bayes_pls_golite062009
substrate-specific transporter activity	1.29730375126024	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	1.28706187447607	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	1.14579511548336	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	0.699203719711999	bayes_pls_golite062009
nucleic acid binding	0.646641337908559	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	0.600852003734846	bayes_pls_golite062009
active transmembrane transporter activity	0.434775387083003	bayes_pls_golite062009
ATP binding	0.41092997612902	bayes_pls_golite062009
adenyl ribonucleotide binding	0.385813421701492	bayes_pls_golite062009
adenyl nucleotide binding	0.377870145186619	bayes_pls_golite062009
DNA binding	0.334939970943935	bayes_pls_golite062009
primary active transmembrane transporter activity	0.294474570607914	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.282352478532746	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.220608508617331	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.219533217661421	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.219157471322311	bayes_pls_golite062009
cation channel activity	0.192467810264152	bayes_pls_golite062009
iron ion transmembrane transporter activity	0.160869143323446	bayes_pls_golite062009
transcription regulator activity	0.147805393867298	bayes_pls_golite062009
protein binding	0.071010918255742	bayes_pls_golite062009
motor activity	0.0492636236578701	bayes_pls_golite062009

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..272]	PSI-BLAST	6.522879	Signal sequence recognition protein Ffh; Signal sequence binding protein Ffh; GTPase domain of the signal sequence recognition protein Ffh

Protein Overview: YLR243W

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: