Protein Overview: BET3

General Information:
Name(s) found:	BET3 / YKR068C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6322921\|ref\|NP_012994.1\| Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles; component of the TRAPP (transport protein particle) complex; Bet3p [Saccharomyces cerevisiae] [NCBI NR] gi\|549628\|sp\|P36149.1\|BET3_YEAST RecName: Full=Transport protein particle 22 kDa subunit; Short=TRAPP 22 kDa subunit [NCBI NR] pir\|\|S38144 hypothetical protein YKR068c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|486601\|emb\|CAA82147.1\| BET3 [Saccharomyces cerevisiae] [NCBI NR] gi\|45269683\|gb\|AAS56222.1\| YKR068C [Saccharomyces cerevisiae] [NCBI NR] gi\|193885347\|pdb\|3CUE\|W Chain W, Crystal Structure Of A Trapp Subassembly Activating The Rab Ypt1p [NCBI NR] gi\|193885346\|pdb\|3CUE\|V Chain V, Crystal Structure Of A Trapp Subassembly Activating The Rab Ypt1p [NCBI NR] gi\|193885341\|pdb\|3CUE\|Q Chain Q, Crystal Structure Of A Trapp Subassembly Activating The Rab Ypt1p [NCBI NR] gi\|193885340\|pdb\|3CUE\|P Chain P, Crystal Structure Of A Trapp Subassembly Activating The Rab Ypt1p [NCBI NR] gi\|193885335\|pdb\|3CUE\|K Chain K, Crystal Structure Of A Trapp Subassembly Activating The Rab Ypt1p [NCBI NR] gi\|193885334\|pdb\|3CUE\|J Chain J, Crystal Structure Of A Trapp Subassembly Activating The Rab Ypt1p [NCBI NR] gi\|193885329\|pdb\|3CUE\|E Chain E, Crystal Structure Of A Trapp Subassembly Activating The Rab Ypt1p [NCBI NR] gi\|193885328\|pdb\|3CUE\|D Chain D, Crystal Structure Of A Trapp Subassembly Activating The Rab Ypt1p [NCBI NR] Transport protein particle 22 kDa subunit OS=Saccharomyces cerevisiae GN=BET3 PE=1 SV=1 [Swiss-Prot] BET3 Protein involved in targeting and fusion of ER to golgi transport vesicles [mips] Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles; component of the TRAPP (transport protein particle) complex [SGD] BET3, Chr XI from 569964-570545, reverse complement [yeast_orfs2] Chr XI from 569964-570545, reverse complement [yeastorf3.fasta] Chr XI from 570545-569964, reverse complement [yeastorf5.fasta] (P36149) Transport protein particle 22 kDa subunit (TRAPP 22 kDa subunit) [4932.FASTACCERV.txt] BET3 SGDID:S0001776, Chr XI from 570551-569970, reverse complement, Verified ORF [yeastflysequest.fasta] Bet3p [Saccharomyces cerevisiae]gi\|486601\|emb\|CAA82147.1\| BET3 [Saccharomyces cerevisiae]gi\|45269683\|gb\|AAS56222.1\| YKR068C [Saccharomyces cerevisiae]gi\|539269\|pir\|\|S38144 hypothetical protein YKR068c - yeast (Saccharomyces cerevisiae)gi\|549628\|sp\|P36 [nrdb_11152004_Chlamydomonas] BET3 SGDID:S000001776, Chr XI from 570551-569970, reverse complement, Verified ORF, "Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles; component of the TRAPP (transport protein part [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles; component of the TRAPP (transport protein particle) complex; Bet3p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] BET3 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YKR068C [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Transport protein particle 22 kDa subunit (TRAPP 22 kDa subunit) [nr-271106-contam.fasta] BET3 SGDID:S000001776, Chr XI from 570551-569970, reverse complement, Verified ORF, "Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles; component of the TRAPP (transport protein particle) complex" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Trafficking protein particle complex subunit BET3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BET3 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] BET3 SGDID:S000001776, Chr XI from 570909-570328, Genome Release 64-1-1, reverse complement, Verified ORF, "Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles; component of the TRAPP (transport protein particle) complex" [yeast-030211-contam.fasta] BET3 SGDID:S000001776, Chr XI from 570909-570328, Genome Release 64-2-1, reverse complement, Verified ORF, "Core component of transport protein particle (TRAPP) complexes I-III; TRAPP complexes are related multimeric guanine nucleotide-exchange factors for the GTPase Ypt1, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII); hydrophilic homodimeric protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles" [20141208_orf_trans.fasta] TR7245\|c0_g1_i1\|g.5072 ORF TR7245\|c0_g1_i1\|g.5072 TR7245\|c0_g1_i1\|m.5072 type:complete len:194 (+) TR7245\|c0_g1_i1:56-637(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] TR5235\|c0_g1_i1\|g.3514 ORF TR5235\|c0_g1_i1\|g.3514 TR5235\|c0_g1_i1\|m.3514 type:complete len:194 (+) TR5235\|c0_g1_i1:57-638(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] YKR068C SGDID:S000001776, Chr XI from 570909-570328, Genome Release 64-1-1, reverse complement, Verified ORF, "Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles; component of the TRAPP (transport protein particle) complex" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_6939\|g.4872 ORF asmbl_6939\|g.4872 asmbl_6939\|m.4872 type:complete len:194 (+) asmbl_6939:55-636(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta] asmbl_6372\|g.5010 ORF asmbl_6372\|g.5010 asmbl_6372\|m.5010 type:complete len:194 (+) asmbl_6372:55-636(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_6645\|g.4284 ORF ID=asmbl_6645\|g.4284 ID=asmbl_6645\|m.4284 type:complete len:194 (+) ID=asmbl_6645:55-636(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta] ID=asmbl_6393\|g.3946 ORF ID=asmbl_6393\|g.3946 ID=asmbl_6393\|m.3946 type:complete len:194 (+) ID=asmbl_6393:55-636(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	193 amino acids
Gene Ontology:
Cellular Component:	TRAPP complex [IDA] Golgi apparatus [IDA]
Biological Process:	ER to Golgi vesicle-mediated transport [IMP]
Molecular Function:	Ras guanyl-nucleotide exchange factor activity [IDA ][IGI] Rab guanyl-nucleotide exchange factor activity [IDA][IGI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSTTQSRSL KAMGEEIWKN KTEKINTELF TLTYGSIVAQ LCQDYERDFN KVNDHLYSMG  60
   61 YNIGCRLIED FLARTALPRC ENLVKTSEVL SKCAFKIFLN ITPNITNWSH NKDTFSLILD 120
  121 ENPLADFVEL PMDAMKSLWY SNILCGVLKG SLEMVQLDCD VWFVSDILRG DSQTEIKVKL 180
  181 NRILKDEIPI GED

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		BET3 BET5 GSG1 KRE11 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
View Details	(MIPS) Mewes HW, et al. (2004)		BET3 BET5 GSG1 KRE11 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
View Details	Krogan NJ, et al. (2006)		BET3 GYP6 TRS20
View Details	Gavin AC, et al. (2006)		BET3 BET5 GSG1 KRE11 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
View Details	Gavin AC, et al. (2002)		BET3 BET5 FKS1 GSG1 KRE11 RVB2 SKN1 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33
View Details	Qiu et al. (2008)		BET3 BET5 GSG1 KRE11 SED5 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	ZDS1	Sample 2- cpn2 from june 2005	McCusker D, et al (2007)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	BET3	Huh WK, et al. (2003)
View Data	BET3 and CHC1	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..193]	PSI-BLAST	86.69897	Crystal structure of Human Bet3

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: BET3

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: