YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: HMS2

General Information:
Name(s) found: HMS2 / YJR147W [SGD]
Description(s) found:
Found 27 descriptions.
SHOW ALL
  • Protein with similarity to heat shock transcription factors; overexpression suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 358 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: pseudohyphal growth [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDATSRMEQP DVFVSKLYHL LQGNAYSNII QWSTDGSKLV IWNPDQFTKV ILERFFGIHT  60
   61 FAAFVKQLSK YNFQKAGRPD CVEFSNIHFQ KDNINSLSLV KAHQSAATPN VAAVNNMNKQ 120
  121 CTFHWDPFKV NSILSKAIGK PSFEKLVKNV DRLQGNLDEL KSTNADSLRI IREINASLQT 180
  181 ISYHQFHAYQ TANFLQENFE AIKKVVCPDS CLQHQQRQPK RPKRYSLLLL IPNASELSET 240
  241 PLMRFAGVFE FMNCSLDTAT QWHPQLHPEA YDLLFVTVSP NMQQEHLIYF KRLRNLLPSF 300
  301 PVIAIINRPV SPQDTSIAPS NYSRYYFHHF LQLGFSDILV SPFTPTQLIT LLSKHLRT

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) HMS2 NAT3 PUF2 RIA1 RPL11A RPL12B, RPL12A RPL13A RPL13B RPL16A RPL16B RPL17B RPL19B, RPL19A RPL21A RPL21B RPL22A RPL22B RPL23B, RPL23A RPL24A RPL24B RPL27B RPL33B RPL35A, RPL35B RPL38 RPL40B, RPL40A RPL41A, RPL41B RPL42B, RPL42A RPL43B, RPL43A RPL5 RPL6A RPL8A RPP0 RPP1B RPP2A RPS0A RPS0B RPS10A RPS11A, RPS11B RPS15 RPS16B, RPS16A RPS17A RPS19B RPS1A RPS21B RPS23B, RPS23A RPS24A, RPS24B RPS26A RPS27A RPS29A RPS29B RPS6A, RPS6B RPS7B RPS8B, RPS8A RPS9B TSR1 YPL199C

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data HMS2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..113] PSI-BLAST 86.124002 Heat-shock transcription factor
    2 View Details [114..253] MSA 1.069986 View MSA. No confident structure predictions are available.
    3 View Details [254..358] deduced N/A Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  3.50995556050336 bayes_pls_golite062009
  • binding
    		•  3.33026160538031 bayes_pls_golite062009
  • DNA binding
    		•  3.22637331076146 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.05427098674 bayes_pls_golite062009
  • transcription factor activity
    		•  2.60537570879007 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.32971938164691 bayes_pls_golite062009
  • transcription activator activity
    		•  1.09351769815632 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.97608021324937 bayes_pls_golite062009
  • protein binding
    		•  0.653872239015235 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.29742933266479 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle