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Protein Overview: IBA57

General Information:
Name(s) found: IBA57 / YJR122W [SGD]
Description(s) found:
Found 29 descriptions.
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  • Mitochondrial matrix protein involved in the incorporation of iron-sulfur clusters into mitochondrial aconitase-type proteins; activates the radical-SAM family members Bio2p and Lip5p; interacts with Ccr4p in the two-hybrid system [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 497 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFISRRCRIK GFTLKNLLWF RSSSTRFVST ESPDASAITK PDGIFNYSLL ENRTYIRIRG  60
   61 PDTVKFLNGL VTSKLLPHFI KKNLTTVEEN EVPTEEGTTK VDPIIPVPEF DARLGNWGLY 120
  121 NEKGIQGPYI SRFGLYSAFL NGKGKLITDT IIYPTPVTVS EQISNYPEYL LELHGNVVDK 180
  181 ILHVLQTHKL ANKIKFEKID HSSLKTWDVE VQFPNLPKDI ENPWFDNLLD PMALPKNSID 240
  241 ANNFAVNVLN SLFNSDPRIL GIYVERRTES MSRHYSTFPQ SFRVVTSEQV DDLSKLFNFN 300
  301 VFDFPFQVNK KASVQVREIR FQKGLIDSTE DYISETLLPL ELNFDFFPNT ISTNKGCYVG 360
  361 QELTARTYAT GILRKRLVPV KLDNYQLLDT DPERKYAEFH IDNVVEKSLA ENEPTLNPFT 420
  421 NKPPERTKRK QRPAGLLISN EGLYGVALLR TEHFSAAFSS DEPVEFYITT TKGENIKITP 480
  481 QKPFWFSDWK NNNGPHK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) CAF16 CAF4 CCR4 CDC36 CDC39 DBF2 DHH1 IBA57 MOB1 MOT2 NOT3 NOT5 POP2
    View Details Qiu et al. (2008) CCR4 CDC36 CDC39 IBA57 POP2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data IBA57 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..132] deduced N/A No confident structure predictions are available.
    2 View Details [133..497] MSA 12.047997 View MSA. No confident structure predictions are available.
    3 View Details [432..497] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  1.65079399897053 bayes_pls_golite062009
  • aminomethyltransferase activity
    		•  0.573831999310668 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  0.464847295845307 bayes_pls_golite062009
  • transferase activity
    		•  0.217873555384951 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.0509405447248159 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle