Protein Overview: OM45

General Information:
Name(s) found:	OM45 / YIL136W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|730224\|sp\|P16547.2\|OM45_YEAST RecName: Full=Mitochondrial outer membrane protein OM45; AltName: Full=Outer membrane protein of 45 kDa [NCBI NR] gi\|6322055\|ref\|NP_012130.1\| Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane; Om45p [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S48398 outer mitochondrial membrane protein, 45K - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|557787\|emb\|CAA86142.1\| om45 [Saccharomyces cerevisiae] [NCBI NR] gi\|51012997\|gb\|AAT92792.1\| YIL136W [Saccharomyces cerevisiae] [NCBI NR] Mitochondrial outer membrane protein OM45 OS=Saccharomyces cerevisiae GN=OM45 PE=1 SV=2 [Swiss-Prot] OM45 Protein of the outer mitochondrial membrane [mips] Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane [SGD] OM45, Chr IX from 93619-94800 [yeast_orfs2] Chr IX from 93619-94800 [yeastorf3.fasta] (P16547) Mitochondrial outer membrane 45 kDa protein [4932.FASTACCERV.txt] OM45 SGDID:S0001398, Chr IX from 93619-94800, Verified ORF [yeastflysequest.fasta] Om45p [Saccharomyces cerevisiae]gi\|51012997\|gb\|AAT92792.1\| YIL136W [Saccharomyces cerevisiae]gi\|557787\|emb\|CAA86142.1\| om45 [Saccharomyces cerevisiae]gi\|630075\|pir\|\|S48398 outer mitochondrial membrane protein, 45K - yeast (Saccharomyces cerevisiae)gi [nrdb_11152004_Chlamydomonas] OM45 SGDID:S000001398, Chr IX from 93619-94800, Verified ORF, "Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YIL136W [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane; Om45p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Mitochondrial outer membrane 45 kDa protein [nr-271106-contam.fasta] om45 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Mitochondrial outer membrane protein OM45 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=OM45 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] OM45 SGDID:S000001398, Chr IX from 93619-94800, Genome Release 64-1-1, Verified ORF, "Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane" [yeast-030211-contam.fasta] OM45 SGDID:S000001398, Chr IX from 93619-94800, Genome Release 64-2-1, Verified ORF, "Mitochondrial outer membrane protein of unknown function; major constituent of the outer membrane, located on the outer (cytosolic) face; protein abundance increases in response to DNA replication stress" [20141208_orf_trans.fasta] TR2296\|c0_g1_i1\|g.1599 ORF TR2296\|c0_g1_i1\|g.1599 TR2296\|c0_g1_i1\|m.1599 type:complete len:394 (+) TR2296\|c0_g1_i1:644-1825(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] YIL136W SGDID:S000001398, Chr IX from 93619-94800, Genome Release 64-1-1, Verified ORF, "Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_8720\|g.6372 ORF asmbl_8720\|g.6372 asmbl_8720\|m.6372 type:complete len:394 (+) asmbl_8720:644-1825(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_8693\|g.5392 ORF ID=asmbl_8693\|g.5392 ID=asmbl_8693\|m.5392 type:complete len:394 (+) ID=asmbl_8693:644-1825(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	393 amino acids
Gene Ontology:
Cellular Component:	integral to mitochondrial outer membrane [IDA] mitochondrion [IDA] mitochondrial outer membrane [IDA ][TAS]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRIIVGSA ALAAAITASI MVREQKAKGQ RREGNVSAYY NGQEYGSSAP PQLGKLHNIK  60
   61 QGIKEDALSL KDALLGVSQK AREEAPKVTK RVISPEEDAQ TRKQLGQKAK DSSSQSIFNW 120
  121 GFSEAERRKA IAIGEFDTAK KRFEEAVDRN EKELLSTVMR EKKAALDRAS IEYERYGRAR 180
  181 DFNELSDKLD QQERNSNPLK RLLKNNTGDA NTEEAAARSV QGWGDTAQEF GREELEEAKR 240
  241 NASSEPSEAQ KRLDELKKIK EKGWFGYNKG EQSEQQIAER VARGLEGWGE TAAQLSKDEM 300
  301 DDLRWNYENS KKQLDKNVSD AMDSLSKAKE DLKQYGSHWW SGWTSKVDND KQALKDEAQK 360
  361 KYDEALKKYD EAKNKFKEWN DKGDGKFWSS KKD

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Ho Y, et al. (2002)		ARG4 AYR1 COR1 CPR6 ERG27 GPT2 LIA1 MAE1 OM45 PCT1 PDA1 PET10 PET9 PIL1 PRE10 PRO3 RET2 RNR2 RTN2 RVS161 SEC18 SEC21 SEC26 SEC27 SEC28 TIF34 TIF35 TPA1 YNL181W

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	ZDS1	Sample 2- cpn2 from june 2005	McCusker D, et al (2007)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	CWC25	OM45	1	Hazbun TR, et al. (2003)

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	OM45	Huh WK, et al. (2003)

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..393]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2