Protein Overview: PRM5

General Information:
Name(s) found:	PRM5 / YIL117C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|731863\|sp\|P40476.1\|YIL7_YEAST RecName: Full=Uncharacterized protein YIL117C [NCBI NR] gi\|6322074\|ref\|NP_012149.1\| Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling; Prm5p [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S48455 probable membrane protein YIL117c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|558689\|emb\|CAA86263.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] gi\|45270056\|gb\|AAS56409.1\| YIL117C [Saccharomyces cerevisiae] [NCBI NR] Uncharacterized protein YIL117C OS=Saccharomyces cerevisiae GN=YIL117C PE=1 SV=1 [Swiss-Prot] PRM5 Pheromone-regulated protein, induced during cell integrity signalling [mips] Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling [SGD] PRM5, Chr IX from 140610-141566, reverse complement [yeast_orfs2] Chr IX from 140610-141566, reverse complement [yeastorf3.fasta] Chr IX from 141566-140610, reverse complement [yeastorf5.fasta] (P40476) Hypothetical 34.7 kDa protein in RHO3-HIS5 intergenic region [4932.FASTACCERV.txt] PRM5 SGDID:S0001379, Chr IX from 141566-140610, reverse complement, Verified ORF [yeastflysequest.fasta] Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signalling [Saccharomyces cerevisiae]gi\|558689\|emb\|CAA86263.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|45270056\|gb\|AAS56409.1\| YIL117C [Sa [nrdb_11152004_Chlamydomonas] PRM5 SGDID:S000001379, Chr IX from 141566-140610, reverse complement, Verified ORF, "Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling; Prm5p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YIL117C [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Hypothetical 34.7 kDa protein in RHO3-HIS5 intergenic region [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] PRM5 SGDID:S000001379, Chr IX from 141569-140613, Genome Release 64-1-1, reverse complement, Verified ORF, "Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling" [yeast-030211-contam.fasta] PRM5 SGDID:S000001379, Chr IX from 141569-140613, Genome Release 64-2-1, reverse complement, Verified ORF, "Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling; PRM5 has a paralog, YNL058C, that arose from the whole genome duplication" [20141208_orf_trans.fasta] YIL117C SGDID:S000001379, Chr IX from 141569-140613, Genome Release 64-1-1, reverse complement, Verified ORF, "Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	318 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [ISS]
Biological Process:	conjugation with cellular fusion [IEP] response to pheromone [IEP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVITIAKRG LPKLTTSTSS TTTASSSSTI TSVASSSSSL PLLSNSTSSS IIPSITPPSR  60
   61 NGNPYILDSG DMPNGTVFIV VGGIAGVIFL AILLWWVITT YSSHRLTRSV QDYESKMFST 120
  121 QHTQFYGDSP YMDYPAKENF QDQVHISESD ISPGNKDESV KDALVSHTNN EKPFLSNFER 180
  181 PLFSLASESN RNSLFISPTG DILYKTRLSK LYQESPRLLQ KPVIMTSDNV STNSLVSTIS 240
  241 SSSASSLDNG NEKEVGEDIR KPAKIASSPS RKLLNSPESD GSVNRNHSKG NLLVVQSKRK 300
  301 PTPSTYLEHM LEGKEQDE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	ZDS1	Sample 3 - cpn + atp, from june 2005	McCusker D, et al (2007)
View Run	VAM3	sample: hx3	Hao Xu, et al. (2010)
View Run	VAM3	Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control).	Hao Xu, et al. (2010)
View Run	VAM3	Sample: HX13 - trans-SNARE complex forms but fusion is blocked.	Hao Xu, et al. (2010)
View Run	VAM3	Sample: HX14 - mixture in detergent (control).	Hao Xu, et al. (2010)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	BUD2	PRM5	2	Unpublished Fields Lab Data
View Screen	PTC4	PRM5	1	Unpublished Fields Lab Data
View Screen	HO	PRM5	1	Unpublished Fields Lab Data
View Screen	RPN9	PRM5	1	Unpublished Fields Lab Data
View Screen	UBC6	PRM5	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	PRM5	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..318]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2