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Protein Overview: RMD8

General Information:
Name(s) found: RMD8 / YFR048W [SGD]
Description(s) found:
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  • gi|836803|dbj|BAA09287.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|22532998|ref|NP_683716.1| Cytosolic protein required for sporulation; Rmd8p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1176024|sp|P43620.1|RMD8_YEAST RecName: Full=Sporulation protein RMD8; AltName: Full=Required for meiotic nuclear division protein 8 [NCBI NR]
  • pir||S56303 probable membrane protein YFR048w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • (P43620) Hypothetical 75.9 kDa protein in SAP155-YMR31 intergenic region [Swiss-Prot]
  • Sporulation protein RMD8 OS=Saccharomyces cerevisiae GN=RMD8 PE=1 SV=1 [Swiss-Prot]
  • RMD8 Cytosolic protein required for sporulation [mips]
  • Cytosolic protein required for sporulation [SGD]
  • YFR048W, Chr VI from 246133-248121 [yeast_orfs2]
  • Chr VI from 246133-248121 [yeastorf3.fasta]
  • RMD8 SGDID:S0001944, Chr VI from 246133-248121, Verified ORF [yeastflysequest.fasta]
  • Cytosolic protein required for sporulation [Saccharomyces cerevisiae]gi|1176024|sp|P43620|YFL8_YEAST Hypothetical 75.9 kDa protein in SAP155-YMR31 intergenic regiongi|1084762|pir||S56303 probable membrane protein YFR048w - yeast (Saccharomyces cerevisia [nrdb_11152004_Chlamydomonas]
  • RMD8 SGDID:S000001944, Chr VI from 246133-248121, Verified ORF, "Cytosolic protein required for sporulation" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • Sporulation protein RMD8 [nr-271106-contam.fasta]
  • Cytosolic protein required for sporulation; Rmd8p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Sporulation protein RMD8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RMD8 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • RMD8 SGDID:S000001944, Chr VI from 246146-248134, Genome Release 64-1-1, Verified ORF, "Cytosolic protein required for sporulation" [yeast-030211-contam.fasta]
  • RMD8 SGDID:S000001944, Chr VI from 246146-248134, Genome Release 64-2-1, Verified ORF, "Cytosolic protein required for sporulation" [20141208_orf_trans.fasta]
  • YFR048W SGDID:S000001944, Chr VI from 246146-248134, Genome Release 64-1-1, Verified ORF, "Cytosolic protein required for sporulation" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 662 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: response to drug [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYKANQPSP GEMPKRSPSI LVTDARTSKN RMSAPFAGHA AGSRKNMENA GVTKSQGVRS  60
   61 SAIGPSPLQS FTHPRRRSSG RFSDISIDNI LSDNSDIPSA RREERLSSSS SDRPRQYERL 120
  121 SSRRKMINPL PPRTSKTSQK LVLIPEDDNL NHFQTLPTNA LDRQRPKVGS MKSNSFDRLP 180
  181 RYSKEKSMAR ITAYNVADGF NLNQLYKFLQ ETHEVSPRLY DECLYVAYTL PLLPGKGGFR 240
  241 IKSNLSKKTM GGKTLIDNLI DTSEQRDHHY EYYSGVETVE DANNNYELET SGNNNNANQD 300
  301 TTTVPDHLPN PVGQQDSFNP MEPQFFAEET PLEIEKRERT ERINMLKKEE NDSDASCGND 360
  361 NNNKNNDKSK LYAVEGNDQY VQSSRSPASP SSISTPSPPS SSQNDFDRVY KMHRDNDHEG 420
  421 NDRHAEIFIF HYGVIVFWNF TEIQEKNILG DITFADYKNL MIRPLDEQDI ETEQFHFEYD 480
  481 RDTERPRIFN DIVTLRSGDH IIELTLSHAI AQSSKLSRFE SRISPILISV TKLPKRLALY 540
  541 GTLGLKREQL LKKSGKLFKL RVDVNLSSTI LDTPEFFWSF EPSLHPLYVA MREYLEIDQR 600
  601 VQVLNDRCKV FLEFFDICVD SVAERNMARV TWWFILVILF GVIFSLTEIF VRYVIIHRHT 660
  661 ST

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) AHA1 BUD3 CNS1 CPR6 DIG2 DNM1 DSF1, YNR073C FRT2 GPA2 HOM6 HSC82 HSP104 HSP82 MBB1 MRPL50 PAM1 PPT1 QNS1 RMD8 RTS1 SMT3 STI1 STP4 TDH1 UTP20 YBL104C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run VAM3 Sample: HX11 - both fusion and trans-SNARE complex formation take place. Hao Xu, et al. (2010)
    View Run VAM3 Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control). Hao Xu, et al. (2010)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RMD8 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..124] deduced N/A No confident structure predictions are available.
    2 View Details [125..274] MSA 1.002966 View MSA. No confident structure predictions are available.
    3 View Details [275..359] deduced N/A No confident structure predictions are available.
    4 View Details [360..662] Pfam 148.091515 Uncharacterised ACR, YagE family COG1723 No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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