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Protein Overview: CBS2

General Information:
Name(s) found: CBS2 / YDR197W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Mitochondrial translational activator of the COB mRNA; interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 389 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial inner membrane [TASLink to PubMed article]
    Biological Process: translation [TASLink to PubMed article]
    Molecular Function: molecular_function [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSIPRVYS LGNSAMTYLL ALRIAQLPSQ PKVPSVVLLL NDQKKLNRFL NNDSKIIVKS  60
   61 SNNNKETYHR QFMASCVPPI LSNGEIAPIE NLIVSDPSSK FITAQLSKYN KSLRPETNIL 120
  121 FLNPSLNLLE HLHRYRWRFD EARPNLFMGF TTPVDVGTIH QEFQLSLKVK GRIQFHIAKI 180
  181 DGFPRMSSTG KSASLSLRGD RQKNEKENNA FYKLFREISR LRSGIGSDLV SFDLHVHGFQ 240
  241 DLFFTELEKL ILESCTEPLL AVYDCVYKKE LLKIPGAQDI IKKLISEQLS IIDRSYPSLN 300
  301 TNPNYSVIFD KERIFSLVMR DLEVNGHKRA KLAQSLNQLN QTNINELNGF FVSLGKYKKC 360
  361 NCKWNDILLT LIKGKQFITK QKALDYHYL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) AEP1 AEP2 CBP1 CBP2 CBP6 CBS1 CBS2 MSS51 PET111 PET112 PET122 PET309 PET494 PET54 SUV3
    View Details Qiu et al. (2008) CBS2 PET309 PET54

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen MPE1 CBS2 2 Unpublished Fields Lab Data
    View Screen HBT1 CBS2 2 Unpublished Fields Lab Data
    View Screen PPM1 CBS2 2 Unpublished Fields Lab Data
    View Screen EUG1 CBS2 2 Unpublished Fields Lab Data
    View Screen IMP4 CBS2 2 Unpublished Fields Lab Data
    View Screen RGD2 CBS2 2 Unpublished Fields Lab Data
    View Screen PGA1 CBS2 2 Unpublished Fields Lab Data
    View Screen SPO21 CBS2 2 Unpublished Fields Lab Data
    View Screen SPO21 CBS2 2 Unpublished Fields Lab Data
    View Screen SPO21 CBS2 2 Unpublished Fields Lab Data
    View Screen BUB1 CBS2 2 Unpublished Fields Lab Data
    View Screen SGT1 CBS2 2 Unpublished Fields Lab Data
    View Screen ACM1 CBS2 2 Unpublished Fields Lab Data
    View Screen NIT2 CBS2 2 Unpublished Fields Lab Data
    View Screen IML1 CBS2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data CBS2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..245] PSI-BLAST 57.522879 Ketopantoate reductase PanE
    2 View Details [246..389] PSI-BLAST 57.522879 Ketopantoate reductase PanE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  0.799708671807187 bayes_pls_golite062009
  • structural molecule activity
    		•  0.75267483298133 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.653719917678334 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.34220594024072 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.285880800622433 bayes_pls_golite062009
  • DNA binding
    		•  0.199566885140605 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0150328330534928 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.59

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle