Protein Overview: ACM1

General Information:
Name(s) found:	ACM1 / YPL267W [SGD]
Description(s) found: Found 27 descriptions. SHOW ALL	Pseudosubstrate inhibitor of the anaphase-promoting complex/cyclosome (APC/C), that suppresses APC/C [Cdh1]-mediated proteolysis of mitotic cyclins; associates with Cdh1p, Bmh1p and Bmh2p; cell cycle regulated protein [SGD]
Organism:	Saccharomyces cerevisiae
Length:	209 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [IGI]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISPSKKRTI LSSKNINQKP RAVVKGNELR SPSKRRSQID TDYALRRSPI KTIQISKAAQ  60
   61 FMLYEETAEE RNIAVHRHNE IYNNNNSVSN ENNPSQVKEN LSPAKICPYE RAFLREGGRI 120
  121 ALKDLSVDEF KGYIQDPLTD ETIPLTLPLG DKKISLPSFI TPPRNSKISI FFTSKHQGQN 180
  181 PETKISRSTD DVSEKKVVRK LSFHVYEDE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	ACM1	BMH2	2	Unpublished Fields Lab Data
View Screen	ACM1	CBS2	2	Unpublished Fields Lab Data
View Screen	ACM1	PPZ2	2	Unpublished Fields Lab Data
View Screen	ACM1	YKL115C	2	Unpublished Fields Lab Data
View Screen	ACM1	PET494	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..209]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2