Protein Overview: STP4

General Information:
Name(s) found:	STP4 / YDL048C [SGD]
Description(s) found: SHOW ONLY BEST	pir\|\|S67581 STP4 protein - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|74676436\|sp\|Q07351.2\|STP4_YEAST RecName: Full=Zinc finger protein STP4 [NCBI NR] gi\|6320155\|ref\|NP_010235.1\| Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p; Stp4p [Saccharomyces cerevisiae] [NCBI NR] gi\|3417404\|emb\|CAA98610.1\| STP4 [Saccharomyces cerevisiae] [NCBI NR] Zinc finger protein STP4 OS=Saccharomyces cerevisiae GN=STP4 PE=1 SV=2 [Swiss-Prot] STP4 Protein involved in pre-tRNA splicing and in uptake of branched-chain amino acids [mips] Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p [SGD] STP4, Chr IV from 366738-368210, reverse complement [yeast_orfs2] Chr IV from 366738-368210, reverse complement [yeastorf3.fasta] Chr IV from 368210-366738, reverse complement [yeastorf5.fasta] >Q07351 (Q07351) STP4 protein [4932.FASTACCERV.txt] STP4 SGDID:S0002206, Chr IV from 368211-366739, reverse complement, Verified ORF [yeastflysequest.fasta] Protein involved in pre-tRNA splicing and in uptake of branched-chain amino acids [Saccharomyces cerevisiae]gi\|3417404\|emb\|CAA98610.1\| STP4 [Saccharomyces cerevisiae]gi\|7493898\|pir\|\|S67581 STP4 protein - yeast (Saccharomyces cerevisiae) [nrdb_11152004_Chlamydomonas] (Q07351) STP4 protein [cerv4932.FASTAC] STP4 SGDID:S000002206, Chr IV from 368211-366739, reverse complement, Verified ORF, "Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] STP4 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p; Stp4p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Zinc finger protein STP4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STP4 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] STP4 SGDID:S000002206, Chr IV from 368211-366739, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p" [yeast-030211-contam.fasta] STP4 SGDID:S000002206, Chr IV from 368211-366739, Genome Release 64-2-1, reverse complement, Verified ORF, "Protein containing a Kruppel-type zinc-finger domain; similar to Stp1p, Stp2p; predicted transcription factor; relative distribution to the nucleus increases upon DNA replication stress; STP4 has a paralog, STP3, that arose from the whole genome duplication" [20141208_orf_trans.fasta] YDL048C SGDID:S000002206, Chr IV from 368211-366739, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	490 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA] mitochondrion [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVSSSFASS IDSVMSHETM SLRRNPPFID TPEKMPNPTA SPNGTIHHLI DPSLPLLSST  60
   61 TSSSRSTLSS TLNSPPPPPL TTSYSSYNSS ACQSITSSPT DNTALAHNSK CYFPHSLSPT 120
  121 PLSSNSSSHV ILPPISSFTN LITVAEREFN GRSNSLHANF TSPVPRTVLD HHRHELTFCN 180
  181 PNNTTGFKTI TPSPPTQHQS ILPTAVDNVP RSKSVSSLPV SGFPPLIVKQ QQQQQLNSSS 240
  241 SASALPSIHS PLTNEHTSRY SSSLKDSAKI TKQRKKKECP ICHNFYANLS THKSTHLTPE 300
  301 DRPHKCPICQ RGFARNNDLI RHKKRHWKDE FMQIYARESD NNSGADDQDD TARTSANNDS 360
  361 DDSNDKLAAS SSSEETKLLK KNQLKSLYKI KGAFKCPYNS TLINLDMEVY PHKSRSLYFE 420
  421 PINCHQTGVF SRCDTFKNHL KALHFEYPPK TKKEDRGVVP GKCKHCGLQF PNVDVWLNKH 480
  481 VGKGCGYSYH

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		GDH2 STP4
View Details	(MIPS) Mewes HW, et al. (2004)		LOS1 SEN15 SEN2 SEN34 SEN54 STP1 STP2 STP3 STP4 TPT1 TRL1
View Details	Krogan NJ, et al. (2006)		AHA1 BUD3 CNS1 CPR6 DIG2 DNM1 DSF1, YNR073C FRT2 GPA2 HOM6 HSC82 HSP104 HSP82 MBB1 MRPL50 PAM1 PPT1 QNS1 RMD8 RTS1 SMT3 STI1 STP4 TDH1 UTP20 YBL104C

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	PAN1	No Comments	Toshima J, et al (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	STP4	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..125]	MSA	3.612996	View MSA. No confident structure predictions are available.
2	View Details	[126..237]	MSA	30.198996	View MSA. Confident ab initio structure predictions are available.
3	View Details	[238..351]	PSI-BLAST	26.39794	Designed zinc finger protein
4	View Details	[352..490]	PSI-BLAST	44.9897	ZIF268

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.79

Protein Overview: STP4

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: