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Protein Overview: YBR139W

General Information:
Name(s) found: YBR139W [SGD]
Description(s) found:
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  • gi|6319615|ref|NP_009697.1| Putative serine type carboxypeptidase with a role in phytochelatin synthesis; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression induced by nitrogen limitation in a GLN3, GAT1-independent manner [NCBI NR]
  • pir||S46008 probable carboxypeptidase C (EC 3.4.16.5) YBR139w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|586548|sp|P38109.1|YBY9_YEAST RecName: Full=Putative serine carboxypeptidase YBR139W [NCBI NR]
  • gi|536436|emb|CAA85097.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • gi|51012813|gb|AAT92700.1| YBR139W [Saccharomyces cerevisiae] [NCBI NR]
  • gi|496869|emb|CAA53497.1| YBR1015 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1582525|prf||2118402N YBR1015 gene [NCBI NR]
  • Putative serine carboxypeptidase YBR139W OS=Saccharomyces cerevisiae GN=YBR139W PE=1 SV=1 [Swiss-Prot]
  • Member of Serine carboxypeptidase family [mips]
  • Putative serine type carboxypeptidase with a role in phytochelatin synthesis; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression induced by nitrogen limitation in a GLN3, GAT1-independent manner [SGD]
  • YBR139W, Chr II from 515622-517148 [yeast_orfs2]
  • Chr II from 515622-517148 [yeastorf3.fasta]
  • Chr II from 515621-517147 [yeastorf4.fasta]
  • Chr II from 515619-517145 [yeastorf5.fasta]
  • (P38109) Putative serine carboxypeptidase in ESR1-IRA1 intergenic region (EC 3.4.16.-) [4932.FASTACCERV.txt]
  • YBR139W SGDID:S0000343, Chr II from 515620-517146, Uncharacterized ORF [yeastflysequest.fasta]
  • YBR139W SGDID:S0000343, Chr II from 515658-517184, Uncharacterized ORF [10112005cervSGD.fasta]
  • Ybr139wp [Saccharomyces cerevisiae]gi|51012813|gb|AAT92700.1| YBR139W [Saccharomyces cerevisiae]gi|496869|emb|CAA53497.1| YBR1015 [Saccharomyces cerevisiae]gi|536436|emb|CAA85097.1| unnamed protein product [Saccharomyces cerevisiae]gi|626843|pir||S460 [nrdb_11152004_Chlamydomonas]
  • YBR139W SGDID:S000000343, Chr II from 515658-517184, Uncharacterized ORF, "Putative serine type Carboxypeptidase; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YBR139W is not an essential gene" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • YBR139W SGDID:S000000343, Chr II from 515658-517184, Verified ORF, "Putative serine type carboxypeptidase with a role in phytochelatin synthesis; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression induced by nitrogen limit [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • YBR1015 gene [nr-271106-contam.fasta]
  • YBR139W [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • YBR1015 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Putative serine carboxypeptidase YBR139W [nr-271106-contam.fasta]
  • Putative serine type Carboxypeptidase; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YBR139W is not an essential gene; Ybr139wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • YBR139W SGDID:S000000343, Chr II from 515658-517184, Verified ORF, "Putative serine type carboxypeptidase with a role in phytochelatin synthesis; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression induced by nitrogen limitation in a GLN3, GAT1-independent manner" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • Putative serine carboxypeptidase YBR139W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YBR139W PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • YBR139W SGDID:S000000343, Chr II from 515664-517190, Genome Release 64-1-1, Verified ORF, "Putative serine type carboxypeptidase with a role in phytochelatin synthesis; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression induced by nitrogen limitation in a GLN3, GAT1-independent manner" [yeast-030211-contam.fasta]
  • YBR139W SGDID:S000000343, Chr II from 515664-517190, Genome Release 64-2-1, Verified ORF, "Putative serine type carboxypeptidase; role in phytochelatin synthesis; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression induced by nitrogen limitation in a GLN3, GAT1-independent manner" [20141208_orf_trans.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 508 amino acids

    Gene Ontology:
    Cellular Component: fungal-type vacuole [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: serine hydrolase activity [IDALink to PubMed article][RCALink to PubMed article]
    carboxypeptidase C activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYLNLVFVL QLLISIKYAS FGRAFSLFED DTTFANLDKQ LKLPQNTQQT LKLDRLNHDD  60
   61 PLFTTFISSV DTDYSLRLRT VDPSKLGIDT VKQWSGYMDY KDSKHFFYWF FESRNDPAND 120
  121 PIILWLNGGP GCSSFTGLLF ELGPSSIGAD MKPIHNPYSW NNNASMIFLE QPLGVGFSYG 180
  181 DEKVSSTKLA GKDAYIFLEL FFEAFPHLRS NDFHIAGESY AGHYIPQIAH EIVVKNPERT 240
  241 FNLTSVMIGN GITDPLIQAD YYEPMACGKG GYHPVLSSEE CEKMSKAAGR CRRLNKLCYA 300
  301 SKSSLPCIVA TAYCDSALLE PYINTGLNVY DIRGPCEDNS TDGMCYTGLR YVDQYMNFPE 360
  361 VQETLGSDVH NYSGCDNDVF TGFLFTGDGS KPFQQYIAEL LNHNIPVLIY AGDKDYICNW 420
  421 LGNHAWSNEL EWINKRRYQR RMLRPWVSKE TGEELGQVKN YGPFTFLRIY DAGHMVPYDQ 480
  481 PEASLEMVNS WISGNRAFSD LSTLENAS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) HCH1 HOR2 LIF1 PIG2 YBR139W YKL069W
    View Details Ho Y, et al. (2002) AAH1 CDC53 PRB1 SAF1 YBR139W
    View Details Qiu et al. (2008) PRC1 YBR139W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run SEC10 No Comments De Craene, J., et al. (2006)
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YBR139W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..87] deduced N/A No confident structure predictions are available.
    2 View Details [88..245]
    [340..382]    		 PSI-BLAST 1496.0 Serine carboxypeptidase II
    3 View Details [246..339]
    [383..508]    		 PSI-BLAST 1496.0 Serine carboxypeptidase II

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • hydrolase activity
    		•  4.09944423676394 bayes_pls_golite062009
  • peptidase activity
    		•  2.49064988313037 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.10044305272656 bayes_pls_golite062009
  • catalytic activity
    		•  1.39629727416851 bayes_pls_golite062009
  • palmitoyl-(protein) hydrolase activity
    		•  1.3250951453762 bayes_pls_golite062009
  • palmitoyl-CoA hydrolase activity
    		•  0.815337671271829 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.541803897301601 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.43631945855397 bayes_pls_golite062009
  • binding
    		•  0.351031277062254 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle