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Protein Overview: WNT5A_RAT

General Information:
Name(s) found: WNT5A_RAT [Swiss-Prot]
Description(s) found:
Found 7 descriptions.
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  • Protein Wnt-5a OS=Rattus norvegicus GN=Wnt5a PE=2 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 380 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [UNKNOWN][IDA]
    cytoplasm [IDA]
    Biological Process: embryonic development [UNKNOWN]
    neural tube development [UNKNOWN]
    tail morphogenesis [UNKNOWN]
    response to hyperoxia [IEP]
    negative regulation of fibroblast growth factor receptor signaling pathway [UNKNOWN]
    positive regulation of response to cytokine stimulus [UNKNOWN]
    positive regulation of JUN kinase activity [UNKNOWN]
    negative chemotaxis [UNKNOWN]
    regulation of branching involved in mammary gland duct morphogenesis [UNKNOWN]
    midgut development [UNKNOWN]
    male gonad development [UNKNOWN]
    positive regulation of cell-cell adhesion [IMP]
    anterior/posterior pattern formation [UNKNOWN]
    JNK cascade [UNKNOWN]
    negative regulation of prostatic bud formation [UNKNOWN]
    positive regulation of NF-kappaB transcription factor activity [UNKNOWN]
    positive regulation of angiogenesis [UNKNOWN]
    embryonic digit morphogenesis [UNKNOWN]
    axis elongation [UNKNOWN]
    lung alveolus development [IEP]
    wound healing [UNKNOWN]
    ameboidal cell migration [UNKNOWN]
    tube closure [UNKNOWN]
    heart looping [UNKNOWN]
    Wnt receptor signaling pathway [UNKNOWN]
    positive regulation of thymocyte apoptosis [UNKNOWN]
    response to testosterone stimulus [IEP]
    positive regulation of epithelial cell proliferation [UNKNOWN]
    positive regulation of peptidyl-serine phosphorylation [UNKNOWN]
    response to organic substance [IEP]
    epithelial cell proliferation involved in mammary gland duct elongation [UNKNOWN]
    urinary bladder development [UNKNOWN]
    neuron differentiation [IEP]
    cochlea morphogenesis [UNKNOWN]
    Wnt receptor signaling pathway, calcium modulating pathway [UNKNOWN]
    positive regulation of protein catabolic process [UNKNOWN]
    positive regulation of mesenchymal cell proliferation [UNKNOWN]
    negative regulation of axon extension involved in axon guidance [UNKNOWN]
    response to organic cyclic substance [IEP]
    mesenchymal-epithelial cell signaling [UNKNOWN]
    lateral sprouting involved in mammary gland duct morphogenesis [UNKNOWN]
    pericardium morphogenesis [UNKNOWN]
    somitogenesis [UNKNOWN]
    morphogenesis of an epithelium [UNKNOWN]
    hypophysis morphogenesis [UNKNOWN]
    inner ear morphogenesis [UNKNOWN]
    negative regulation of epithelial cell proliferation [UNKNOWN]
    positive regulation of T cell chemotaxis [UNKNOWN]
    response to estradiol stimulus [IEP]
    limb morphogenesis [UNKNOWN]
    prostate gland development [IEP]
    cellular protein localization [UNKNOWN]
    cervix development [UNKNOWN]
    vagina development [UNKNOWN]
    positive regulation of cartilage development [UNKNOWN]
    positive regulation of protein kinase C signaling cascade [UNKNOWN]
    positive regulation of cell proliferation [UNKNOWN]
    uterus development [UNKNOWN]
    chondrocyte differentiation [UNKNOWN]
    protein amino acid phosphorylation [UNKNOWN]
    convergent extension [UNKNOWN]
    convergent extension involved in organogenesis [UNKNOWN]
    mammary gland branching involved in thelarche [UNKNOWN]
    positive regulation of macrophage cytokine production [UNKNOWN]
    embryonic limb morphogenesis [UNKNOWN]
    neural tube closure [UNKNOWN]
    cellular response to calcium ion [UNKNOWN]
    negative regulation of mesenchymal cell proliferation [UNKNOWN]
    positive regulation of fibroblast proliferation [UNKNOWN]
    response to glucocorticoid stimulus [IEP]
    Wnt receptor signaling pathway through beta-catenin [UNKNOWN]
    Wnt receptor signaling pathway, planar cell polarity pathway [UNKNOWN]
    positive regulation of endothelial cell migration [UNKNOWN]
    cell migration [UNKNOWN]
    lung development [UNKNOWN]
    positive regulation of meiosis [UNKNOWN]
    negative regulation of fat cell differentiation [UNKNOWN]
    gut morphogenesis [UNKNOWN]
    hindgut morphogenesis [UNKNOWN]
    pancreatic B cell development [UNKNOWN]
    positive regulation of cytokine secretion during immune response [UNKNOWN]
    negative regulation of BMP signaling pathway [UNKNOWN]
    negative regulation of Wnt receptor signaling pathway through beta-catenin [UNKNOWN]
    cellular response to lipopolysaccharide [UNKNOWN]
    dopaminergic neuron differentiation [UNKNOWN]
    negative regulation of apoptosis [UNKNOWN]
    establishment of planar polarity [UNKNOWN]
    positive regulation of protein amino acid phosphorylation [UNKNOWN]
    cell differentiation [IEP]
    hemopoietic stem cell proliferation [UNKNOWN]
    positive regulation of peptidyl-threonine phosphorylation [UNKNOWN]
    positive regulation of endothelial cell proliferation [UNKNOWN]
    cellular response to interferon-gamma [UNKNOWN]
    primitive streak formation [UNKNOWN]
    positive regulation of chemokine biosynthetic process [UNKNOWN]
    Molecular Function: frizzled binding [UNKNOWN]
    protein binding [UNKNOWN]
    frizzled-2 binding [UNKNOWN]
    receptor binding [UNKNOWN]
    molecular_function [ND]
    receptor tyrosine kinase-like orphan receptor binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKPIGILSP GVALGTAGGA MSSKFFLMAL ATFFSFAQVV IEANSWWSLG MNNPVQMSEV  60
   61 HIIGAQPLCS QLAGLSQGQK KLCHLYQDHM QYIGEGAKTG IKECQYQFRH RRWNCSTVDN 120
  121 TSVFGRVMQI GSRETAFTYA VSAAGVVNAM SRACREGELS TCGCSRAARP KDLPRDWLWG 180
  181 GCGDNIDYGY RFAKEFVDAR ERERIHAKGS YESARILMNL HNNEAGRRTV YNLADVACKC 240
  241 HGVSGSCSLK TCWLQLADFR KVGDALKEKY DSAAAMRLNS RGKLVQVNSR FNSPTTQDLV 300
  301 YIDPSPDYCV RNESTGSLGT QGRLCNKTSE GMDGCELMCC GRGYDQFKTV QTERCHCKFH 360
  361 WCCYVKCKKC TEIVDQFVCK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle