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Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold. The process of joining together the neural folds at either end of the neural tube. The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube. The process by which closure points are established at multiple points and along the neural rostrocaudal axis. The process whereby the neural folds are fused extending from the initial closure points. Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow. The morphogenesis of an embryonic epithelium into a tube-shaped structure. The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline. Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube. The process by which anatomical structures are generated and organized during the embryonic phase. Morphogenesis pertains to the creation of form. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants. The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. The process by which the anatomical structures of embryonic epithelia are generated and organized. Morphogenesis pertains to the creation of form. The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube. The process by which the anatomical structures of epithelia are generated and organized. Morphogenesis pertains to the creation of form. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: neural tube closure
Acc: GO:0001843
Aspect: Biological Process
Desc: The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.
Proteins in PDR annotated with:
   This term: 67 [Search]
   Term or descendants: 71 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0001843 - neural tube closure (interactive image map)
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