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Protein Overview: VATA_YEAST

General Information:
Name(s) found: VATA_YEAST [Swiss-Prot]
Description(s) found:
  • V-type proton ATPase catalytic subunit A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VMA1 PE=1 SV=3 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1071 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGAIENARK EIKRISLEDH AESEYGAIYS VSGPVVIAEN MIGCAMYELV KVGHDNLVGE  60
   61 VIRIDGDKAT IQVYEETAGL TVGDPVLRTG KPLSVELGPG LMETIYDGIQ RPLKAIKEES 120
  121 QSIYIPRGID TPALDRTIKW QFTPGKFQVG DHISGGDIYG SVFENSLISS HKILLPPRSR 180
  181 GTITWIAPAG EYTLDEKILE VEFDGKKSDF TLYHTWPVRV PRPVTEKLSA DYPLLTGQRV 240
  241 LDALFPCVQG GTTCIPGAFG CGKTVISQSL SKYSNSDAII YVGCFAKGTN VLMADGSIEC 300
  301 IENIEVGNKV MGKDGRPREV IKLPRGRETM YSVVQKSQHR AHKSDSSREV PELLKFTCNA 360
  361 THELVVRTPR SVRRLSRTIK GVEYFEVITF EMGQKKAPDG RIVELVKEVS KSYPISEGPE 420
  421 RANELVESYR KASNKAYFEW TIEARDLSLL GSHVRKATYQ TYAPILYEND HFFDYMQKSK 480
  481 FHLTIEGPKV LAYLLGLWIG DGLSDRATFS VDSRDTSLME RVTEYAEKLN LCAEYKDRKE 540
  541 PQVAKTVNLY SKVVRGNGIR NNLNTENPLW DAIVGLGFLK DGVKNIPSFL STDNIGTRET 600
  601 FLAGLIDSDG YVTDEHGIKA TIKTIHTSVR DGLVSLARSL GLVVSVNAEP AKVDMNGTKH 660
  661 KISYAIYMSG GDVLLNVLSK CAGSKKFRPA PAAAFARECR GFYFELQELK EDDYYGITLS 720
  721 DDSDHQFLLA NQVVVHNCGE RGNEMAEVLM EFPELYTEMS GTKEPIMKRT TLVANTSNMP 780
  781 VAAREASIYT GITLAEYFRD QGKNVSMIAD SSSRWAEALR EISGRLGEMP ADQGFPAYLG 840
  841 AKLASFYERA GKAVALGSPD RTGSVSIVAA VSPAGGDFSD PVTTATLGIT QVFWGLDKKL 900
  901 AQRKHFPSIN TSVSYSKYTN VLNKFYDSNY PEFPVLRDRM KEILSNAEEL EQVVQLVGKS 960
  961 ALSDSDKITL DVATLIKEDF LQQNGYSTYD AFCPIWKTFD MMRAFISYHD EAQKAVANGA1020
 1021 NWSKLADSTG DVKHAVSSSK FFEPSRGEKE VHGEFEKLLS TMQERFAEST D

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] Pfam 21.886057 No description for PF02874.7 was found. No confident structure predictions are available.
    2 View Details [85..189] MSA 2.05899 View MSA. No confident structure predictions are available.
    3 View Details [190..261] deduced N/A No confident structure predictions are available.
    4 View Details [262..512] PSI-BLAST 80.0 VMA1-derived endonuclease (VDE) PI-Scei intein; VMA1-derived endonuclease (VDE) PI-SceI
    5 View Details [513..1071] PSI-BLAST 113.0 F1 ATP synthase alpha subunit, domain 3; F1 ATP synthase alpha subunit, domain 1; Central domain of alpha subunit of F1 ATP synthase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrogen ion transmembrane transporter activity
    		•  8.99485812867371 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  8.43809246013427 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  7.28612792538764 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  6.56211055461575 bayes_pls_golite062009
  • proton-transporting ATPase activity, rotational mechanism
    		•  3.88373794136406 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.39040720727162 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.28894636799771 bayes_pls_golite062009
  • hydrogen-exporting ATPase activity, phosphorylative mechanism
    		•  3.20056737251701 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.03916263027565 bayes_pls_golite062009
  • transporter activity
    		•  2.9325438450934 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.77909183361556 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.67498718917813 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.60251056808401 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.58430117129985 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.58115131779782 bayes_pls_golite062009
  • hydrolase activity
    		•  2.48023456865742 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  2.38650577592563 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  2.38284234201968 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  2.34368052096144 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  2.33928814826072 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  2.33884554716207 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  2.28786776436738 bayes_pls_golite062009
  • cation-transporting ATPase activity
    		•  2.2242188318911 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.19267030982632 bayes_pls_golite062009
  • binding
    		•  2.15223415484989 bayes_pls_golite062009
  • ATPase activity
    		•  2.14491816112038 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.8085602148752 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.53938373974092 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.50098700711558 bayes_pls_golite062009
  • DNA binding
    		•  1.19194387475416 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  1.12292194267086 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.12203014375349 bayes_pls_golite062009
  • catalytic activity
    		•  0.942640875796745 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.875943780299382 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.869710683000949 bayes_pls_golite062009
  • helicase activity
    		•  0.802129193518991 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.714145134870091 bayes_pls_golite062009
  • nucleotide binding
    		•  0.708394757192331 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.70300395089804 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.702990562850678 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.630907399726593 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.606831357648651 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.520434833402482 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.520010821042307 bayes_pls_golite062009
  • potassium channel activity
    		•  0.516313726033988 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  0.329657633591245 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  0.329657633591245 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  0.29111329295693 bayes_pls_golite062009
  • cation channel activity
    		•  0.267140200199812 bayes_pls_golite062009
  • ATP binding
    		•  0.221274151647827 bayes_pls_golite062009
  • protein binding
    		•  0.201869978778282 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.198698067988182 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.194178388079667 bayes_pls_golite062009
  • structural molecule activity
    		•  0.191568396055768 bayes_pls_golite062009
  • ion channel activity
    		•  0.17671388431308 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  0.168531365787205 bayes_pls_golite062009
  • translation regulator activity
    		•  0.165004576559811 bayes_pls_golite062009
  • channel activity
    		•  0.164130750223518 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.164130750223518 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.154272377180496 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.144513585153713 bayes_pls_golite062009
  • transcription factor activity
    		•  0.101575043176033 bayes_pls_golite062009
  • four-way junction helicase activity
    		•  0.100226648459719 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle