| Protein: | Csk-PH |
| Organism: | Drosophila melanogaster |
| Length: | 805 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Csk-PH.
| Description | E-value | Query Range |
Subject Range |
|
|
471.0 | [0..1] | [805..43] |
|
Region A: Residues: [1-189] |
1 11 21 31 41 51
| | | | | |
1 MSESIAIGFL QYIITINYDD EEAQARKTSH EKSQKPKPKP EENHKEKEAI SRKASGEGDL 60
61 ITVEIKQGLL RKQTATTTTG QAMNSHATAT QNGQTTVVGH HRGFSQPSVT VAAAAATGST 120
121 AGDPWFLQTT GHQMPPTAPL RHNKRPAPQP NAVLGAGSSG TAPGSAVGAV LLHQQQLSQS 180
181 QPHIVPPSI
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [190-342] |
1 11 21 31 41 51
| | | | | |
1 PPHHHHHREN NVHPIQAGAA AALHLSSHAL NSHNLISSAS NHSPKSPSQT QQQQQTTNQQ 60
61 QQQQQQQASH SILSTFAPAP TVAAVQPAGS QSVAGTAAAV AAVAQQQQQQ HLQLLANCPP 120
121 GGAGLMSSSL NAAQMGMHGA ERALPPKSLA LSG
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [343-805] |
1 11 21 31 41 51
| | | | | |
1 SQHGSNMLLH TAPQPPQASQ PAAVVGVSGS GSAGMSTSLH SFDINGVTAG SGVNASSAWS 60
61 SGSTTAMNHA SLSPTALAPQ QGRSRCEVKL NAMPWFHGSI TRDEAEHLLQ PREDGLFLVR 120
121 ESTNFPGDYT LCVCFQSKVE HYRVKYLENK LTIDDEEYFE NLGQLVAHYE ADADGLCTQL 180
181 IKCLPKLGKQ EFCINSKDFV DKGWVIPEAE LQLRESIGKG EFGDVMLGIL RNEKVAVKML 240
241 KDEGAVQKFL AEASVMTTLE HDNLVKFIGL VFTSKHLYLV TEYMSKGSLV DYLRSRGRQH 300
301 ITKKDQIIFA YDTASGMEYL EAKKVVHRDL AARNVLISED CVAKVSDFGL AREECYNLDV 360
361 GKLPIKWTAP EALKNGRFSN KSDMWSFGIL LWEIYSFGRV PYPRIPLADV VKHVEVGYKM 420
421 EAPEGCPPEI YEMMRQAWDL NPAKRPTFAE LKVKLQLLNN ATA
|
| Detection Method: | |
| Confidence: | 102.0 |
| Match: | 1k9aA |
| Description: | Carboxyl-terminal src kinase (csk) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 4.41722924924158 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| actin binding | 3.91045208670052 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 3.43994026029707 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| CD8 receptor binding | 3.34636716492159 | bayes_pls_golite062009 |
| protein binding | 3.13677730481089 | bayes_pls_golite062009 |
| binding | 3.06905798270146 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| actin filament binding | 2.72908433443928 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.65451266834284 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.4913932444423 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 2.46424348876434 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| SH2 domain binding | 2.08937039830657 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 1.9016235206634 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine kinase activity | 1.66669268613198 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| vinculin binding | 1.63216315345235 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| PTB domain binding | 1.56656184134104 | bayes_pls_golite062009 |
| growth factor binding | 1.53863828216563 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 1.42275431028856 | bayes_pls_golite062009 |
| molecular transducer activity | 1.34867629228264 | bayes_pls_golite062009 |
| signal transducer activity | 1.34867629228264 | bayes_pls_golite062009 |
| transporter activity | 1.30447542854757 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| tubulin binding | 1.13686658158825 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 1.10045286406485 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 1.10045286406485 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.08558010881058 | bayes_pls_golite062009 |
| cation channel activity | 1.04999722123563 | bayes_pls_golite062009 |
| structural molecule activity | 0.989403012920596 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.820987609295422 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 0.80673395326897 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.75189004129952 | bayes_pls_golite062009 |
| microtubule binding | 0.734274677384472 | bayes_pls_golite062009 |
| JUN kinase kinase kinase kinase activity | 0.546647574638943 | bayes_pls_golite062009 |
| insulin binding | 0.546269851452869 | bayes_pls_golite062009 |
| structural constituent of muscle | 0.52430033936893 | bayes_pls_golite062009 |
| activin binding | 0.510364757301021 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| 3-phosphoinositide-dependent protein kinase binding | 0.372842462336059 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.371928447183203 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.287189255116606 | bayes_pls_golite062009 |
| channel activity | 0.287189255116606 | bayes_pls_golite062009 |
| insulin receptor binding | 0.275913005279959 | bayes_pls_golite062009 |
| kinase binding | 0.26752427107238 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.261869836686301 | bayes_pls_golite062009 |
| ion channel activity | 0.241519346930618 | bayes_pls_golite062009 |
| insulin receptor activity | 0.188254408239569 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 0.150740450460731 | bayes_pls_golite062009 |
| receptor binding | 0.0742205785215131 | bayes_pls_golite062009 |
| JUN kinase kinase kinase activity | 0.0613131034808199 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| cation binding | 0.046173055856133 | bayes_pls_golite062009 |
| metal ion binding | 0.046173055856133 | bayes_pls_golite062009 |
| ion binding | 0.0389662058697694 | bayes_pls_golite062009 |
| protein kinase binding | 0.00674998152095019 | bayes_pls_golite062009 |
