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View Structure Prediction Details

Protein: CE19650
Organism: Caenorhabditis elegans
Length: 395 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE19650.

Description E-value Query
Range		 Subject
Range
gi|187039119, gi... - gi|39585223|emb|CAE57466.1| Hypothetical protein CBG00431 [Caenorhabditis briggsae], gi|187039119|em...
gi|157754295 - gi|157754295|ref|XP_001669491.1| Hypothetical protein CBG00431 [Caenorhabditis briggsae AF16]
 266.0 [0..4] [395..2]

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Predicted Domain #1
Region A:
Residues: [1-81] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVESATNSS SEESIFHEQT RKLFRLCDTK HIGLIGQSDL ETLVDLIPQD DLHKIARFIG  60
   61 DQKVNEQAFC RILKAIVNQS L

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [82-195] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQNMAKNEVE IPCILDKSQY LEESSLEDEM REIEQNKSYL DDPLTKILKK ELEEIKNYED  60
   61 FQVRNEQVLD NIIIKKPLYR PIQPEQSIPK VSSLAEELNA IGKKVLQKEE IEEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.39794
Match: 1pujA
Description: Probable GTPase YlqF
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [196-395] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTQPDRIFKV VFVGDSAVGK TCFLHRFCHN RFKPLFNATI GVDFTVKTMK IPPNRAIAMQ  60
   61 LWDTAGQERF RSITKQYFRK ADGVVLMFDV TSEQSFLNVR NWIDSVRAGV DDATVMCLVG 120
  121 NKMDLFGSDI ARSAVYRAAE KLAVEFKIPF FETSAYTGFG IDTCMRQMAE NLQRREDNHL 180
  181 EEALKLDINS NYKKRSWCCI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.0
Match: 2bcgY
Description: Structure of doubly prenylated Ypt1:GDI complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
motor activity 4.04927796049806 bayes_pls_golite062009
microtubule motor activity 3.91769993918004 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
hydrolase activity 2.73675310079844 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
primary active transmembrane transporter activity 2.61775212528604 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.61467977505707 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.57552435627908 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.57107347424517 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.57054427875021 bayes_pls_golite062009
microfilament motor activity 2.51786963027655 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
ATPase activity, coupled 2.43862163407966 bayes_pls_golite062009
cytoskeletal protein binding 2.4101693596493 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
G-protein coupled receptor activity 2.3505608190884 bayes_pls_golite062009
actin binding 2.2973522188675 bayes_pls_golite062009
nucleic acid binding 2.21184938313192 bayes_pls_golite062009
DNA binding 1.94055378599526 bayes_pls_golite062009
tubulin binding 1.92557767696163 bayes_pls_golite062009
substrate-specific transporter activity 1.91091452720653 bayes_pls_golite062009
guanyl nucleotide binding 1.89320355239381 bayes_pls_golite062009
guanyl ribonucleotide binding 1.88721318481223 bayes_pls_golite062009
GTP binding 1.87900088157196 bayes_pls_golite062009
purine ribonucleotide binding 1.85943679361938 bayes_pls_golite062009
ribonucleotide binding 1.85937484083653 bayes_pls_golite062009
purine nucleotide binding 1.8521191028835 bayes_pls_golite062009
nucleotide binding 1.84603132945448 bayes_pls_golite062009
microtubule binding 1.84561785126784 bayes_pls_golite062009
transcription regulator activity 1.83584389083042 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 1.81972511638668 bayes_pls_golite062009
kinase activity 1.80889641165674 bayes_pls_golite062009
protein transporter activity 1.71214667007262 bayes_pls_golite062009
GTPase activity 1.6309422514633 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.60386625568858 bayes_pls_golite062009
ATP binding 1.5859264197035 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.56325751172863 bayes_pls_golite062009
adenyl ribonucleotide binding 1.55520429131224 bayes_pls_golite062009
adenyl nucleotide binding 1.53158018507951 bayes_pls_golite062009
GDP-dissociation inhibitor binding 1.53046363842187 bayes_pls_golite062009
signal recognition particle binding 1.46975774710831 bayes_pls_golite062009
antigen binding 1.43656260286121 bayes_pls_golite062009
apolipoprotein receptor activity 1.31055516357904 bayes_pls_golite062009
syntaxin-13 binding 1.31055516357904 bayes_pls_golite062009
apolipoprotein A-I receptor activity 1.31055516357904 bayes_pls_golite062009
apolipoprotein A-I binding 1.31055516357904 bayes_pls_golite062009
actin filament binding 1.28204719195916 bayes_pls_golite062009
transmembrane receptor activity 1.26314334516725 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
DNA-dependent ATPase activity 1.2155186842031 bayes_pls_golite062009
receptor activity 1.20313362488821 bayes_pls_golite062009
helicase activity 1.16085745407703 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.14475274823167 bayes_pls_golite062009
signal transducer activity 1.13474466330485 bayes_pls_golite062009
molecular transducer activity 1.13474466330485 bayes_pls_golite062009
protein kinase activity 1.12864835254143 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
ion transmembrane transporter activity 0.977237423302079 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.971476020912368 bayes_pls_golite062009
DNA polymerase activity 0.928091843881235 bayes_pls_golite062009
actin-dependent ATPase activity 0.92105578610354 bayes_pls_golite062009
protein methyltransferase activity 0.876296121718575 bayes_pls_golite062009
transcription activator activity 0.739301862805678 bayes_pls_golite062009
DNA helicase activity 0.72881469450553 bayes_pls_golite062009
transcription factor activity 0.697256579145077 bayes_pls_golite062009
protein-DNA loading ATPase activity 0.650964453464311 bayes_pls_golite062009
histone methyltransferase activity 0.63002958837536 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.59513742813869 bayes_pls_golite062009
ATP-dependent helicase activity 0.59513742813869 bayes_pls_golite062009
nucleotide kinase activity 0.56979593127581 bayes_pls_golite062009
plus-end-directed microtubule motor activity 0.567883621045161 bayes_pls_golite062009
cation transmembrane transporter activity 0.557919489256916 bayes_pls_golite062009
DNA clamp loader activity 0.543512707823441 bayes_pls_golite062009
ribonucleoprotein binding 0.53788302029845 bayes_pls_golite062009
protein transmembrane transporter activity 0.46552249844591 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.444874730945263 bayes_pls_golite062009
drug transmembrane transporter activity 0.38711726712063 bayes_pls_golite062009
protein serine/threonine kinase activity 0.345873656782869 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.325013574811283 bayes_pls_golite062009
receptor binding 0.309955875731734 bayes_pls_golite062009
peptide binding 0.304703625340488 bayes_pls_golite062009
structure-specific DNA binding 0.249173645231486 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.22150712609541 bayes_pls_golite062009
structural constituent of ribosome 0.208665086324262 bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity 0.12351419478929 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.123304946374679 bayes_pls_golite062009
double-stranded DNA binding 0.0781650226500197 bayes_pls_golite062009
metal ion transmembrane transporter activity 0.0775601177068852 bayes_pls_golite062009
DNA strand annealing activity 0.0682259328353787 bayes_pls_golite062009
G-protein-coupled receptor binding 0.0436504490626262 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0111338193708552 bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity 0.00571427458217011 bayes_pls_golite062009
macromolecule transmembrane transporter activity 0.00571427458217011 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle