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View Structure Prediction Details

Protein: rab-7
Organism: Caenorhabditis elegans
Length: 209 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rab-7.

Description E-value Query
Range		 Subject
Range
gi|421942, gi|311907 - pir||S34253 GTP-binding protein, ras-related - common tobacco, gi|311907|emb|CAA51011.1| ras-related...
 236.0 [0..3] [208..2]
gi|7643790 - gi|7643790|gb|AAF65510.1| small GTP-binding protein [Capsicum annuum]
 236.0 [0..3] [208..2]
gi|1053067 - gi|1053067|gb|AAA80680.1| small GTP-binding protein
 235.0 [0..3] [208..2]
ARA5_ARATH - Ras-related protein ARA-5 - Arabidopsis thaliana (Mouse-ear cress)
 234.0 [0..3] [208..57]
gi|1616614 - gi|1616614|emb|CAA69701.1| small GTP-binding protein [Nicotiana plumbaginifolia]
 233.0 [0..3] [207..2]
gi|303732, gi|738941 - gi|738941|prf||2001457J GTP-binding protein, gi|303732|dbj|BAA02117.1| GTP-binding protein [Pisum sa...
 233.0 [0..3] [208..2]
RIC1_ORYSJ - Ras-related protein RIC1 OS=Oryza sativa subsp. japonica GN=RIC1 PE=2 SV=2
gi|125526416 - gi|125526416|gb|EAY74530.1| hypothetical protein OsI_02420 [Oryza sativa Indica Group]
RIC1_ORYSA - Ras-related protein RIC1 - Oryza sativa (Rice)
 232.0 [0..3] [208..2]
gi|50738954 - gi|50738954|ref|XP_419342.1| PREDICTED: similar to ras-related protein [Gallus gallus]
 232.0 [0..7] [208..197]

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Predicted Domain #1
Region A:
Residues: [1-209] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGTRKKALL KVIILGDSGV GKTSLMNQYV NRRFSNQYKA TIGADFLTRD VNIDDRTVTL  60
   61 QIWDTAGQER FQSLGVAFYR GADCCVLAFD VTNAASFKSL DSWRDEFLIQ ASPRDPDHFP 120
  121 FVLLGNKVDL ESQRAVSSKR AQSWCQTKGN IPYYEVSAKE ALNVEAAFLA IARDALARES 180
  181 QETNDFPEFP DQIRLNPNQQ NQQNSGCNC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.0
Match: 1vg0B
Description: The crystal structures of the REP-1 protein in complex with monoprenylated Rab7 protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transporter activity 3.10463051760206 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
actin binding 2.84620358490972 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.74389108884083 bayes_pls_golite062009
pyrophosphatase activity 2.67097555143215 bayes_pls_golite062009
cytoskeletal protein binding 2.66896300219871 bayes_pls_golite062009
hydrolase activity 2.65461298232951 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.65161658635465 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.64849912301318 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
primary active transmembrane transporter activity 2.39629638016861 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.39600931083427 bayes_pls_golite062009
microfilament motor activity 2.37164398259429 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.36051733655256 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.35906629925754 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.35679406876731 bayes_pls_golite062009
amine transmembrane transporter activity 2.29486577878686 bayes_pls_golite062009
ATPase activity 2.2625504298178 bayes_pls_golite062009
ATPase activity, coupled 2.24901251684901 bayes_pls_golite062009
actin filament binding 2.1683792904715 bayes_pls_golite062009
guanyl nucleotide binding 1.89320355239381 bayes_pls_golite062009
guanyl ribonucleotide binding 1.88721318481223 bayes_pls_golite062009
GTP binding 1.87900088157196 bayes_pls_golite062009
organic acid transmembrane transporter activity 1.77111739879769 bayes_pls_golite062009
carboxylic acid transmembrane transporter activity 1.75695995185278 bayes_pls_golite062009
substrate-specific transporter activity 1.65609907941094 bayes_pls_golite062009
GTPase activity 1.6309422514633 bayes_pls_golite062009
nucleic acid binding 1.49633029954726 bayes_pls_golite062009
motor activity 1.49368359124081 bayes_pls_golite062009
DNA binding 1.48341220422804 bayes_pls_golite062009
microtubule motor activity 1.47358567315228 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.3182108176243 bayes_pls_golite062009
transcription regulator activity 1.30136714640988 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
ATP binding 0.98146619596929 bayes_pls_golite062009
adenyl ribonucleotide binding 0.949788783884952 bayes_pls_golite062009
adenyl nucleotide binding 0.931486373329219 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
protein methyltransferase activity 0.876296121718575 bayes_pls_golite062009
ion transmembrane transporter activity 0.704934361725919 bayes_pls_golite062009
kinase activity 0.691112783105676 bayes_pls_golite062009
molecular transducer activity 0.683309012097319 bayes_pls_golite062009
signal transducer activity 0.683309012097319 bayes_pls_golite062009
histone methyltransferase activity 0.63002958837536 bayes_pls_golite062009
amino acid transmembrane transporter activity 0.585668369219566 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.499834566483656 bayes_pls_golite062009
drug transmembrane transporter activity 0.38711726712063 bayes_pls_golite062009
transcription activator activity 0.374651542607188 bayes_pls_golite062009
transcription factor activity 0.341088753451767 bayes_pls_golite062009
signal recognition particle binding 0.29390189699022 bayes_pls_golite062009
cation transmembrane transporter activity 0.282397764628576 bayes_pls_golite062009
protein transporter activity 0.217249710833262 bayes_pls_golite062009
sequence-specific DNA binding 0.106147926780353 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.0430764033739892 bayes_pls_golite062009
protein kinase activity 0.0364322017534667 bayes_pls_golite062009
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