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View Structure Prediction Details

Protein: arl-1
Organism: Caenorhabditis elegans
Length: 180 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for arl-1.

Description E-value Query
Range		 Subject
Range
gi|50738954 - gi|50738954|ref|XP_419342.1| PREDICTED: similar to ras-related protein [Gallus gallus]
 178.0 [0..17] [179..200]
gi|37360618 - gi|37360618|dbj|BAC98287.1| mKIAA3012 protein [Mus musculus]
 178.0 [0..1] [179..49]
gi|148230336, gi... - gi|27924279|gb|AAH45014.1| Rab1-prov protein [Xenopus laevis], gi|148230336|ref|NP_001080138.1| RAB1...
gi|52345478, gi|... - gi|52345478|ref|NP_001004787.1| RAB1A, member RAS oncogene family [Xenopus (Silurana) tropicalis], g...
 178.0 [0..1] [179..1]
gi|114675154 - gi|114675154|ref|XP_001147785.1| PREDICTED: similar to GTP-binding protein RAB11B [Pan troglodytes]
 177.0 [0..1] [178..131]
rab-1 - RAS-related protein status:Confirmed UniProt:Q9UAQ6 protein_id:AAC69218.1
 177.0 [0..1] [179..1]
CRE16067, FL81_1... - RP15185 WBGene00061078 locus:Cre-rab-1 status:Confirmed, null
gi|157761211 - gi|157761211|ref|XP_001672948.1| Hypothetical protein CBG01077 [Caenorhabditis briggsae AF16]
gi|39588485, gi|... - gi|39588485|emb|CAE58008.1| Hypothetical protein CBG01077 [Caenorhabditis briggsae], gi|187038224|em...
 177.0 [0..1] [179..1]
gi|109081641 - gi|109081641|ref|XP_001103732.1| PREDICTED: similar to RAB11a, member RAS oncogene family [Macaca mu...
 177.0 [0..1] [178..89]
gi|53733986 - gb|AAH83951.1| Unknown (protein for MGC:97957) [Xenopus laevis]
gi|55741705 - ref|NP_001003153.1| RAB1A, member RAS oncogene family [Canis familiaris]
gi|120419448, gi... - gi|76629653|ref|XP_869337.1| PREDICTED: similar to RAB1, member RAS oncogene family isoform 2 [Bos t...
gi|109103156 - gi|109103156|ref|XP_001090072.1| PREDICTED: similar to RAB1, member RAS oncogene family isoform 4 [M...
gi|61355917, gi|... - gi|61355926|gb|AAX41191.1| RAB1A member RAS oncogene family [synthetic construct], gi|61355917|gb|AA...
tr|G1TCS8|G1TCS8... - pep:novel chromosome:oryCun2:2:121177308:121212010:1 gene:ENSOCUG00000017003 transcript:ENSOCUT00000...
RAB1A - RAB1A, member RAS oncogene family
RAB1A_RAT - Ras-related protein Rab-1A OS=Rattus norvegicus GN=Rab1A PE=1 SV=3
RAB1A_CANLF - Ras-related protein Rab-1A OS=Canis lupus familiaris GN=RAB1A PE=1 SV=3
gi|159906367 - gi|159906367|gb|ABX10872.1| RAB1A [Capra hircus]
RAB1A_MOUSE - Ras-related protein Rab-1A OS=Mus musculus GN=Rab1A PE=1 SV=3
tr|M3VYP9|M3VYP9... - RAB1A, member RAS oncogene family OS=Felis catus GN=RAB1A PE=4 SV=1
gi|149727528 - gi|149727528|ref|XP_001493347.1| PREDICTED: similar to RAB1A, member RAS oncogene family [Equus caba...
 177.0 [0..1] [179..1]
gi|61365844, gi|... - gi|61365844|gb|AAX42772.1| RAB1A member RAS oncogene family [synthetic construct], gi|54695924|gb|AA...
 177.0 [0..1] [179..1]
RIC1_ORYSJ - Ras-related protein RIC1 OS=Oryza sativa subsp. japonica GN=RIC1 PE=2 SV=2
gi|125526416 - gi|125526416|gb|EAY74530.1| hypothetical protein OsI_02420 [Oryza sativa Indica Group]
RIC1_ORYSA - Ras-related protein RIC1 - Oryza sativa (Rice)
 176.0 [0..17] [179..9]

Back

Predicted Domain #1
Region A:
Residues: [1-180] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGVMSYFRG LFGAREMRIL ILGLDGAGKT TILYRLQVGE VVTTIPTIGF NVEQVEYKNL  60
   61 KFQVWDLGGQ TSIRPYWRCY YANTDAIIYV VDSADRDRVG ISRQELATML QEDELQGAVL 120
  121 AVLANKQDIA GCLTETEVYK ALGLDALRNR TIQIFKTSAS KGEGLDPAMD WLANQLQQKK 180
  181

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.69897
Match: 1r8qA
Description: FULL-LENGTH ARF1-GDP-MG IN COMPLEX WITH BREFELDIN A AND A SEC7 DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
microtubule motor activity 4.51968578934603 bayes_pls_golite062009
motor activity 4.04927796049806 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
structural constituent of muscle 2.82808660259595 bayes_pls_golite062009
tubulin binding 2.67743463093593 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
primary active transmembrane transporter activity 2.61775212528604 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.61467977505707 bayes_pls_golite062009
microtubule binding 2.59155206524122 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.57552435627908 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.57107347424517 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.57054427875021 bayes_pls_golite062009
NAD(P)+-protein-arginine ADP-ribosyltransferase activity 2.56769246638533 bayes_pls_golite062009
microfilament motor activity 2.51786963027655 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
ATPase activity, coupled 2.43862163407966 bayes_pls_golite062009
cytoskeletal protein binding 2.4101693596493 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
actin binding 2.2973522188675 bayes_pls_golite062009
amine transmembrane transporter activity 2.29486577878686 bayes_pls_golite062009
nucleic acid binding 2.09956015274464 bayes_pls_golite062009
transcription regulator activity 2.09345198747025 bayes_pls_golite062009
substrate-specific transporter activity 1.91091452720653 bayes_pls_golite062009
guanyl nucleotide binding 1.89320355239381 bayes_pls_golite062009
guanyl ribonucleotide binding 1.88721318481223 bayes_pls_golite062009
GTP binding 1.87900088157196 bayes_pls_golite062009
DNA binding 1.87765278833074 bayes_pls_golite062009
alpha-tubulin binding 1.792591628112 bayes_pls_golite062009
organic acid transmembrane transporter activity 1.77111739879769 bayes_pls_golite062009
carboxylic acid transmembrane transporter activity 1.75695995185278 bayes_pls_golite062009
protein transporter activity 1.71214667007262 bayes_pls_golite062009
RNA helicase activity 1.63960194106079 bayes_pls_golite062009
GTPase activity 1.6309422514633 bayes_pls_golite062009
ATP-dependent RNA helicase activity 1.61735400124552 bayes_pls_golite062009
RNA-dependent ATPase activity 1.60404584546501 bayes_pls_golite062009
hydrolase activity 1.57549510726226 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.56325751172863 bayes_pls_golite062009
signal recognition particle binding 1.46975774710831 bayes_pls_golite062009
plus-end-directed microtubule motor activity 1.38366133153678 bayes_pls_golite062009
microtubule plus-end binding 1.36713729043205 bayes_pls_golite062009
actin filament binding 1.28204719195916 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
ATP binding 0.98146619596929 bayes_pls_golite062009
ion transmembrane transporter activity 0.977237423302079 bayes_pls_golite062009
adenyl ribonucleotide binding 0.949788783884952 bayes_pls_golite062009
adenyl nucleotide binding 0.931486373329219 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
actin-dependent ATPase activity 0.92105578610354 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
kinase activity 0.691112783105676 bayes_pls_golite062009
molecular transducer activity 0.683309012097319 bayes_pls_golite062009
signal transducer activity 0.683309012097319 bayes_pls_golite062009
transcription factor activity 0.682439846757997 bayes_pls_golite062009
transmembrane receptor activity 0.661834961742057 bayes_pls_golite062009
beta-tubulin binding 0.654735466720932 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.652333406433794 bayes_pls_golite062009
receptor activity 0.633514002718998 bayes_pls_golite062009
DNA strand annealing activity 0.631634545479169 bayes_pls_golite062009
helicase activity 0.6191010101321 bayes_pls_golite062009
amino acid transmembrane transporter activity 0.585668369219566 bayes_pls_golite062009
cation transmembrane transporter activity 0.557919489256916 bayes_pls_golite062009
ribonucleoprotein binding 0.53788302029845 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.499834566483656 bayes_pls_golite062009
microtubule-severing ATPase activity 0.491769258942331 bayes_pls_golite062009
drug transmembrane transporter activity 0.38711726712063 bayes_pls_golite062009
transition metal ion transmembrane transporter activity 0.305627755818843 bayes_pls_golite062009
ATP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 0.213018989352421 bayes_pls_golite062009
structural constituent of ribosome 0.208665086324262 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.123304946374679 bayes_pls_golite062009
cell surface binding 0.0454774504404609 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.0430764033739892 bayes_pls_golite062009
protein kinase activity 0.0364322017534667 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0111338193708552 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle