| Protein: | Caki-PB |
| Organism: | Drosophila melanogaster |
| Length: | 898 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Caki-PB.
| Description | E-value | Query Range |
Subject Range |
|
|
748.0 | [0..1] | [898..1] |
|
Region A: Residues: [1-346] |
1 11 21 31 41 51
| | | | | |
1 MTEDEILFDD VYELCEVIGK GPFSIVRRCI HRESNQQFAV KIVDVAKFTA SPGLSTADLK 60
61 REATICHMLK HPHIVELLET YSSEGMLYMV FEFMEGSDLC FEVVRRAVAG FVYSEAVACH 120
121 YMRQILEALR YCHENDILHR DVRPACALLA TVDNSAPVKL GGFGSAIQLP GTRETIETHG 180
181 RVGCPHYMAP EVVTRRLYGK GCDVWGAGVM LHVLLSGRLP FLGSGVRLQQ SVARGRLSFE 240
241 APEWKSISAN AKDLVMKMLA ANPHHRLSIT EVLDHPWIRD RDKLQRTHLA DTVEELKRYN 300
301 ARRKLKGAVQ AIAGGTNMDP LYATDADMPI TGATDEWADE EAGIEA
|
| Detection Method: |  |
| Confidence: | 75.09691 |
| Match: | 2bdwA |
| Description: | Crystal Structure of the Auto-Inhibited Kinase Domain of Calcium/Calmodulin Activated Kinase II |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [347-391] |
1 11 21 31 41 51
| | | | | |
1 VQRILDCLDD IYSLQDAHVD ADVLRDMLRD NRLHQFLQLF DRIAA
|
| Detection Method: | |
| Confidence: | 14.075721 |
| Match: | PF02828.7 |
| Description: | No description for PF02828.7 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [392-488] |
1 11 21 31 41 51
| | | | | |
1 TVVTSNGRAP AAEAVGRCRD VLEQLSSTSG GNSLGGKYAK EELMRLLAAP HMQALLHSHD 60
61 VVARDVYGEE ALRVTPPPMV PYLNGDELDN VEGGELQ
|
| Detection Method: | |
| Confidence: | 2.52 |
| Match: | 1zl8B |
| Description: | NMR structure of L27 heterodimer from C. elegans Lin-7 and H. sapiens Lin-2 scaffold proteins |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [489-591] |
1 11 21 31 41 51
| | | | | |
1 HVTRVRLVQF QKNTDEPMGI TLKMTEDGRC IVARIMHGGM IHRQATLHVG DEIREINGQP 60
61 VQHQSVGQLQ RMLREARGSV TFKIVPSYRS APPPCEIFVR AQF
|
| Detection Method: | |
| Confidence: | 10.30103 |
| Match: | 1kwaA |
| Description: | Cask/Lin-2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cytoskeletal protein binding | 3.60106431937699 | bayes_pls_golite062009 |
| protein binding | 3.40921081688513 | bayes_pls_golite062009 |
| binding | 3.2595117613307 | bayes_pls_golite062009 |
| actin binding | 3.17546881601441 | bayes_pls_golite062009 |
| transcription regulator activity | 2.16834620509051 | bayes_pls_golite062009 |
| kinase activity | 1.60310055540266 | bayes_pls_golite062009 |
| structural constituent of muscle | 1.55801612135974 | bayes_pls_golite062009 |
| molecular transducer activity | 1.51162321843898 | bayes_pls_golite062009 |
| signal transducer activity | 1.51162321843898 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.42576125485675 | bayes_pls_golite062009 |
| PDZ domain binding | 1.4161955255054 | bayes_pls_golite062009 |
| transcription activator activity | 1.37255187012662 | bayes_pls_golite062009 |
| actin filament binding | 1.36043531087419 | bayes_pls_golite062009 |
| cyclase inhibitor activity | 1.19377184850067 | bayes_pls_golite062009 |
| guanylate cyclase inhibitor activity | 1.19377184850067 | bayes_pls_golite062009 |
| transporter activity | 1.18978519116375 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.07211582292329 | bayes_pls_golite062009 |
| transferase activity | 1.02891276124789 | bayes_pls_golite062009 |
| structural molecule activity | 0.906026957959903 | bayes_pls_golite062009 |
| receptor binding | 0.867295068429704 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.755223974149211 | bayes_pls_golite062009 |
| G-protein-coupled receptor binding | 0.665461219385567 | bayes_pls_golite062009 |
| protein domain specific binding | 0.64214865642772 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.549085929250683 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 0.449763185979101 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.252733105474942 | bayes_pls_golite062009 |
| myosin binding | 0.24204561023371 | bayes_pls_golite062009 |
| cytokine activity | 0.200378971638035 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.182094987832726 | bayes_pls_golite062009 |
| alpha-actinin binding | 0.0801784133682708 | bayes_pls_golite062009 |
| transcription factor binding | 0.0283953080227368 | bayes_pls_golite062009 |
|
Region A: Residues: [592-703] |
1 11 21 31 41 51
| | | | | |
1 DYNPLDDELI PCAQAGISFQ VGDILQIISK DDHHWWQARL DTVGGSAGLI PSPELQEWRI 60
61 ACQTVDKTKQ EQVNCSIFGR KKKQCRDKYL AKHNAIFDTL DVVTYEEVVK VP
|
| Detection Method: | |
| Confidence: | 12.522879 |
| Match: | 1t0hA |
| Description: | Crystal structure of the Rattus norvegicus voltage gated calcium channel beta subunit isoform 2a |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| cytoskeletal protein binding | 4.41722924924158 | bayes_pls_golite062009 |
| actin binding | 4.40611495471342 | bayes_pls_golite062009 |
| actin filament binding | 3.14048820255876 | bayes_pls_golite062009 |
| protein binding | 3.13677730481089 | bayes_pls_golite062009 |
| binding | 3.06905798270146 | bayes_pls_golite062009 |
| molecular transducer activity | 1.80011194349017 | bayes_pls_golite062009 |
| signal transducer activity | 1.80011194349017 | bayes_pls_golite062009 |
| transporter activity | 1.30447542854757 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.08558010881058 | bayes_pls_golite062009 |
| vinculin binding | 1.06590166080776 | bayes_pls_golite062009 |
| structural molecule activity | 0.989403012920596 | bayes_pls_golite062009 |
| structural constituent of muscle | 0.91790790672461 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.820987609295422 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.570864043201529 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.371928447183203 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.277388904131159 | bayes_pls_golite062009 |
| receptor binding | 0.0742205785215131 | bayes_pls_golite062009 |
|
Region A: Residues: [704-898] |
1 11 21 31 41 51
| | | | | |
1 VGDPNFQRKT LVLLGAHGVG RRHIKNTLIS KYPDKYAYPI PHTTRPAKPE EENGRSYYFV 60
61 SHDEMMADIG ANEYLEYGTH EDAMYGTKLD TIRRIHTEGK MAILDVEPQA LKILRTAEFT 120
121 PYVVFIAAPS LQNIADYDGS LERLAKESEM LRQLYGHFFD LTIVNNDISE TIATLETAID 180
181 RVHTTPQWVP VSWLY
|
| Detection Method: | |
| Confidence: | 59.0 |
| Match: | 1kgdA |
| Description: | Guanylate kinase-like domain of Cask |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| motor activity | 3.73454248797903 | bayes_pls_golite062009 |
| microtubule motor activity | 3.635272252933 | bayes_pls_golite062009 |
| transporter activity | 3.10463051760206 | bayes_pls_golite062009 |
| transmembrane transporter activity | 2.95886887664984 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 2.95079405147356 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.87427509025394 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 2.85499564954033 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 2.85178667290149 | bayes_pls_golite062009 |
| actin binding | 2.7930150868804 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| primary active transmembrane transporter activity | 2.61775212528604 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven transmembrane transporter activity | 2.61467977505707 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 2.57552435627908 | bayes_pls_golite062009 |
| ATPase activity, coupled to transmembrane movement of substances | 2.57107347424517 | bayes_pls_golite062009 |
| ATPase activity, coupled to movement of substances | 2.57054427875021 | bayes_pls_golite062009 |
| nucleic acid binding | 2.51683451033161 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 2.50494515048649 | bayes_pls_golite062009 |
| ATPase activity, coupled | 2.43862163407966 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.4101693596493 | bayes_pls_golite062009 |
| ATPase activity | 2.39535714892224 | bayes_pls_golite062009 |
| DNA binding | 2.12258000781149 | bayes_pls_golite062009 |
| transcription regulator activity | 2.09345198747025 | bayes_pls_golite062009 |
| microfilament motor activity | 1.94043121469819 | bayes_pls_golite062009 |
| tubulin binding | 1.92557767696163 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.91091452720653 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.85943679361938 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.85937484083653 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.8521191028835 | bayes_pls_golite062009 |
| nucleotide binding | 1.84603132945448 | bayes_pls_golite062009 |
| microtubule binding | 1.84561785126784 | bayes_pls_golite062009 |
| kinase activity | 1.80889641165674 | bayes_pls_golite062009 |
| actin filament binding | 1.69345106007864 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.60386625568858 | bayes_pls_golite062009 |
| ATP binding | 1.5859264197035 | bayes_pls_golite062009 |
| hydrolase activity | 1.57549510726226 | bayes_pls_golite062009 |
| calmodulin-dependent protein kinase activity | 1.56774112771668 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.56325751172863 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.55520429131224 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.53158018507951 | bayes_pls_golite062009 |
| hydrogen ion transporting ATP synthase activity, rotational mechanism | 1.46040955642981 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 1.23094623498843 | bayes_pls_golite062009 |
| protein binding | 1.22129154759482 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.14475274823167 | bayes_pls_golite062009 |
| signal transducer activity | 1.13474466330485 | bayes_pls_golite062009 |
| molecular transducer activity | 1.13474466330485 | bayes_pls_golite062009 |
| protein kinase activity | 1.12864835254143 | bayes_pls_golite062009 |
| actin-dependent ATPase activity | 1.02902153401888 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 0.977589506905452 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.977237423302079 | bayes_pls_golite062009 |
| transcription activator activity | 0.889929694023098 | bayes_pls_golite062009 |
| transcription factor activity | 0.887108427603557 | bayes_pls_golite062009 |
| transferase activity | 0.871779313294914 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 0.864424650691313 | bayes_pls_golite062009 |
| GTPase activity | 0.83849854735032 | bayes_pls_golite062009 |
| DNA helicase activity | 0.75415390146713 | bayes_pls_golite062009 |
| guanyl nucleotide binding | 0.656009904481476 | bayes_pls_golite062009 |
| guanyl ribonucleotide binding | 0.64416740142962 | bayes_pls_golite062009 |
| GTP binding | 0.643084645864898 | bayes_pls_golite062009 |
| plus-end-directed microtubule motor activity | 0.567883621045161 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.557919489256916 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.543891899378373 | bayes_pls_golite062009 |
| protein transporter activity | 0.498432226280822 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.41398614759796 | bayes_pls_golite062009 |
| receptor activity | 0.381142123108547 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.355770151889237 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.345873656782869 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.243902356228423 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.208665086324262 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 0.123304946374679 | bayes_pls_golite062009 |
| centromeric DNA binding | 0.120185906020979 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 0.0775601177068852 | bayes_pls_golite062009 |
| helicase activity | 0.0775311459068899 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.0111338193708552 | bayes_pls_golite062009 |
