YRC Public Data Repository - Protein Structure Prediction

Protein:	Arf51F-PA, Arf51...
Organism:	Drosophila melanogaster
Length:	175 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Arf51F-PA, Arf51....

Description	E-value	Query Range	Subject Range
gi\|50738954 - gi\|50738954\|ref\|XP_419342.1\| PREDICTED: similar to ras-related protein [Gallus gallus]	182.0	[0..2]	[174..188]
gi\|109105440 - gi\|109105440\|ref\|XP_001118047.1\| PREDICTED: similar to RAB1B, member RAS oncogene family [Macaca mul...	181.0	[0..10]	[174..75]
RIC1_ORYSJ - Ras-related protein RIC1 OS=Oryza sativa subsp. japonica GN=RIC1 PE=2 SV=2 gi\|125526416 - gi\|125526416\|gb\|EAY74530.1\| hypothetical protein OsI_02420 [Oryza sativa Indica Group] RIC1_ORYSA - Ras-related protein RIC1 - Oryza sativa (Rice)	180.0	[0..10]	[174..5]
gi\|303734, gi\|738942 - gi\|738942\|prf\|\|2001457K GTP-binding protein, gi\|303734\|dbj\|BAA02118.1\| GTP-binding protein [Pisum sa... gi\|1098293, gi\|4... - pir\|\|S41430 GTP-binding protein, ras-like (clone vfa-ypt1) - fava bean, gi\|452359\|emb\|CAA82707.1\| g...	180.0	[0..10]	[174..5]
RIC1_ORYSA - (P40392) Ras-related protein RIC1	180.0	[0..10]	[174..5]
gi\|1370166 - gi\|1370166\|emb\|CAA98160.1\| RAB1C [Lotus japonicus]	180.0	[0..10]	[174..5]
gi\|28924807, gi\|... - gi\|32418088\|ref\|XP_329522.1\| GTP-BINDING PROTEIN YPT1 [Neurospora crassa], gi\|28924807\|gb\|EAA33910.1... gi\|85109909 - gi\|85109909\|ref\|XP_963146.1\| GTP-BINDING PROTEIN YPT1 [Neurospora crassa OR74A]	180.0	[0..4]	[174..39]
gi\|421942, gi\|311907 - pir\|\|S34253 GTP-binding protein, ras-related - common tobacco, gi\|311907\|emb\|CAA51011.1\| ras-related...	179.0	[0..10]	[174..5]
gi\|4586580 - gi\|4586580\|dbj\|BAA76422.1\| rab-type small GTP-binding protein [Cicer arietinum]	179.0	[0..10]	[174..5]
gi\|114638536 - gi\|114638536\|ref\|XP_001150399.1\| PREDICTED: similar to RAB1B, member RAS oncogene family [Pan troglo...	179.0	[0..10]	[174..59]

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Predicted Domain #1

Region A:
Residues: [1-175]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKLLSKIFG NKEMRILMLG LDAAGKTTIL YKLKLGQSVT TIPTVGFNVE TVTYKNVKFN  60
   61 VWDVGGQDKI RPLWRHYYTG TQGLIFVVDC ADRDRIDEAR TELHRIINDR EMRDAIILIF 120
  121 ANKQDLPDAM KPHEIQEKLG LTRIRDRNWY VQPSCATSGD GLSEGLIWLT SNHKL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.39794
Match:	2a5dA
Description:	Structural basis for the activation of cholera toxin by human ARF6-GTP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
microtubule motor activity	4.51968578934603	bayes_pls_golite062009
motor activity	4.04927796049806	bayes_pls_golite062009
transporter activity	3.10463051760206	bayes_pls_golite062009
transmembrane transporter activity	2.95886887664984	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.89122312915795	bayes_pls_golite062009
structural constituent of muscle	2.82808660259595	bayes_pls_golite062009
pyrophosphatase activity	2.81593838944939	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.79724985811732	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.79347973548337	bayes_pls_golite062009
tubulin binding	2.67743463093593	bayes_pls_golite062009
binding	2.64537357529343	bayes_pls_golite062009
primary active transmembrane transporter activity	2.61775212528604	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	2.61467977505707	bayes_pls_golite062009
microtubule binding	2.59155206524122	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	2.57552435627908	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	2.57107347424517	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	2.57054427875021	bayes_pls_golite062009
NAD(P)+-protein-arginine ADP-ribosyltransferase activity	2.56769246638533	bayes_pls_golite062009
microfilament motor activity	2.51786963027655	bayes_pls_golite062009
active transmembrane transporter activity	2.50494515048649	bayes_pls_golite062009
ATPase activity	2.44176688200537	bayes_pls_golite062009
ATPase activity, coupled	2.43862163407966	bayes_pls_golite062009
cytoskeletal protein binding	2.4101693596493	bayes_pls_golite062009
actin binding	2.2973522188675	bayes_pls_golite062009
amine transmembrane transporter activity	2.29486577878686	bayes_pls_golite062009
nucleic acid binding	2.09956015274464	bayes_pls_golite062009
transcription regulator activity	2.09345198747025	bayes_pls_golite062009
substrate-specific transporter activity	1.91091452720653	bayes_pls_golite062009
guanyl nucleotide binding	1.89320355239381	bayes_pls_golite062009
guanyl ribonucleotide binding	1.88721318481223	bayes_pls_golite062009
GTP binding	1.87900088157196	bayes_pls_golite062009
DNA binding	1.87765278833074	bayes_pls_golite062009
alpha-tubulin binding	1.792591628112	bayes_pls_golite062009
organic acid transmembrane transporter activity	1.77111739879769	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	1.75695995185278	bayes_pls_golite062009
protein transporter activity	1.71214667007262	bayes_pls_golite062009
hydrolase activity	1.6901766958628	bayes_pls_golite062009
GTPase activity	1.6309422514633	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.56325751172863	bayes_pls_golite062009
plus-end-directed microtubule motor activity	1.38366133153678	bayes_pls_golite062009
signal recognition particle binding	1.37344611158364	bayes_pls_golite062009
microtubule plus-end binding	1.36713729043205	bayes_pls_golite062009
actin filament binding	1.28204719195916	bayes_pls_golite062009
protein binding	1.22129154759482	bayes_pls_golite062009
RNA helicase activity	1.02424782546779	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
ATP binding	0.98146619596929	bayes_pls_golite062009
ion transmembrane transporter activity	0.977237423302079	bayes_pls_golite062009
RNA-dependent ATPase activity	0.95986988363392	bayes_pls_golite062009
adenyl ribonucleotide binding	0.949788783884952	bayes_pls_golite062009
ATP-dependent RNA helicase activity	0.94128341275411	bayes_pls_golite062009
adenyl nucleotide binding	0.931486373329219	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
actin-dependent ATPase activity	0.92105578610354	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
kinase activity	0.691112783105676	bayes_pls_golite062009
molecular transducer activity	0.683309012097319	bayes_pls_golite062009
signal transducer activity	0.683309012097319	bayes_pls_golite062009
transcription factor activity	0.682439846757997	bayes_pls_golite062009
transmembrane receptor activity	0.661834961742057	bayes_pls_golite062009
beta-tubulin binding	0.654735466720932	bayes_pls_golite062009
receptor activity	0.633514002718998	bayes_pls_golite062009
amino acid transmembrane transporter activity	0.585668369219566	bayes_pls_golite062009
cation transmembrane transporter activity	0.557919489256916	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.499834566483656	bayes_pls_golite062009
microtubule-severing ATPase activity	0.491769258942331	bayes_pls_golite062009
ribonucleoprotein binding	0.44184908500323	bayes_pls_golite062009
drug transmembrane transporter activity	0.38711726712063	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	0.305627755818843	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	0.213018989352421	bayes_pls_golite062009
structural constituent of ribosome	0.208665086324262	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.123304946374679	bayes_pls_golite062009
helicase activity	0.0775311459068899	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.0430764033739892	bayes_pls_golite062009
protein kinase activity	0.0364322017534667	bayes_pls_golite062009
structural constituent of cytoskeleton	0.0111338193708552	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: