| Protein: | sax-PB |
| Organism: | Drosophila melanogaster |
| Length: | 535 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sax-PB.
| Description | E-value | Query Range |
Subject Range |
|
|
392.0 | [0..1] | [535..36] |
|
Region A: Residues: [1-169] |
1 11 21 31 41 51
| | | | | |
1 MELSSASSAH LNGKELPAVP QNSVQTHPRY KCYSCEPPCR DPYEFTHTCQ NAIQCWKSRT 60
61 RDADGQVQES RGCSTSPDQL PMICSQNSLK INGPSKRNTG KFVNVVCCAG DYCNEGDFPE 120
121 LLPFDSNDVT VITADTSSIS KMLVAVLGPF LVIALLGAVT IFFIRRSHR
|
| Detection Method: |  |
| Confidence: | 7.522879 |
| Match: | 1rewC |
| Description: | Structural refinement of the complex of bone morphogenetic protein 2 and its type IA receptor |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transmembrane receptor protein serine/threonine kinase binding | 3.29432547587631 | bayes_pls_golite062009 |
| transforming growth factor beta receptor binding | 3.29432547587631 | bayes_pls_golite062009 |
| transforming growth factor beta binding | 2.91714500246524 | bayes_pls_golite062009 |
| receptor activity | 2.74055213309696 | bayes_pls_golite062009 |
| U-plasminogen activator receptor activity | 2.67622889349209 | bayes_pls_golite062009 |
| receptor serine/threonine kinase binding | 2.63843756028069 | bayes_pls_golite062009 |
| signal transducer activity | 2.51859905018984 | bayes_pls_golite062009 |
| molecular transducer activity | 2.51859905018984 | bayes_pls_golite062009 |
| protein binding | 2.27773193148456 | bayes_pls_golite062009 |
| growth factor binding | 2.11370016324137 | bayes_pls_golite062009 |
| SMAD binding | 2.11166655078306 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.93573786819729 | bayes_pls_golite062009 |
| binding | 1.78861011884769 | bayes_pls_golite062009 |
| polysaccharide binding | 1.72562399286061 | bayes_pls_golite062009 |
| cytokine binding | 1.30600639196836 | bayes_pls_golite062009 |
| type I transforming growth factor beta receptor binding | 1.10571389507211 | bayes_pls_golite062009 |
| receptor binding | 0.899783960746717 | bayes_pls_golite062009 |
| enzyme binding | 0.61951403712284 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.227519165953748 | bayes_pls_golite062009 |
| pattern binding | 0.21003196804615 | bayes_pls_golite062009 |
|
Region A: Residues: [170-535] |
1 11 21 31 41 51
| | | | | |
1 KRLAASRTKQ DPEAYLVNDE LLRATSAGDS TLREYLQHSV TSGSGSGLPL LVQRTLAKQV 60
61 TLIECIGRGK YGEVWRGHWH GESIAVKIFF SRDEESWKRE TEIYSTILLR HENILGFIGS 120
121 DMTSRNSCTQ LWLMTHYYPL GSLFDHLNRN ALSHNDMVWI CLSIANGLVH LHTEIFGKQG 180
181 KPAMAHRDLK SKNILVTSNG SCVIADFGLA VTHSHVTGQL DLGNNPKVGT KRYMAPEVLD 240
241 ESIDLECFEA LRRTDIYAFG LVLWEVCRRT ISCGIAEEYK VPFYDVVPMD PSFEDMRKVV 300
301 CIDNYRPSIP NRWSSDSLMT GMSKLMKECW HQNPDVRLPA LRIKKTIHKL ASADEKIRLD 360
361 FDEVCV
|
| Detection Method: | |
| Confidence: | 75.69897 |
| Match: | 1b6cB |
| Description: | Type I TGF-beta receptor R4 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| activin receptor activity | 9.43409082112081 | bayes_pls_golite062009 |
| activin binding | 7.11944534332244 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 6.41728494915949 | bayes_pls_golite062009 |
| activin receptor activity, type I | 6.1393596497059 | bayes_pls_golite062009 |
| protein kinase activity | 5.63683237027974 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.04467222534257 | bayes_pls_golite062009 |
| kinase activity | 4.85903980916957 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.46123870227889 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 3.37600307408153 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 3.37600307408153 | bayes_pls_golite062009 |
| transferase activity | 3.26787750561728 | bayes_pls_golite062009 |
| follistatin binding | 3.25716461198789 | bayes_pls_golite062009 |
| transmembrane receptor activity | 3.1965684217331 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 2.97315540587667 | bayes_pls_golite062009 |
| receptor activity | 2.96273889901429 | bayes_pls_golite062009 |
| signal transducer activity | 2.85730457922199 | bayes_pls_golite062009 |
| molecular transducer activity | 2.85730457922199 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| growth factor binding | 2.61235080252818 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 2.57601476622612 | bayes_pls_golite062009 |
| type II transforming growth factor beta receptor binding | 2.54478169273822 | bayes_pls_golite062009 |
| actin binding | 2.42703012169921 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.38494443043195 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| binding | 2.10874590528357 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| insulin receptor activity | 2.08642574110801 | bayes_pls_golite062009 |
| fibroblast growth factor 1 binding | 2.08248852174113 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| activin receptor activity, type II | 1.93639573827674 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.90879495821405 | bayes_pls_golite062009 |
| MAP kinase kinase kinase kinase activity | 1.70795227184717 | bayes_pls_golite062009 |
| actin filament binding | 1.68048469859634 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| JUN kinase kinase kinase kinase activity | 1.54033709235083 | bayes_pls_golite062009 |
| transforming growth factor beta binding | 1.46877913443522 | bayes_pls_golite062009 |
| fibroblast growth factor binding | 1.39074764291742 | bayes_pls_golite062009 |
| amine binding | 1.3051205627964 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| PTB domain binding | 1.14009984975509 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| cytokine receptor binding | 1.08904623349766 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| insulin binding | 1.03564126441771 | bayes_pls_golite062009 |
| SMAD binding | 1.02108562119195 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| stem cell factor receptor activity | 0.877914726874139 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase binding | 0.620804584416924 | bayes_pls_golite062009 |
| transforming growth factor beta receptor binding | 0.620804584416924 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.610230065465794 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.58590430118616 | bayes_pls_golite062009 |
| transcription regulator activity | 0.527255160265651 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.450699332958421 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| DNA binding | 0.392505747359251 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type II | 0.365530951355731 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.34434685718027 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 0.33253160432275 | bayes_pls_golite062009 |
| peptide hormone binding | 0.312169974523858 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.294256794094724 | bayes_pls_golite062009 |
| inhibin binding | 0.29024207998068 | bayes_pls_golite062009 |
| inhibin beta-B binding | 0.29024207998068 | bayes_pls_golite062009 |
| inhibin beta-A binding | 0.29024207998068 | bayes_pls_golite062009 |
| nucleic acid binding | 0.289778841954859 | bayes_pls_golite062009 |
| collagen binding | 0.249197530511006 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| polysaccharide binding | 0.229808864843639 | bayes_pls_golite062009 |
| MAP kinase activity | 0.213371031328104 | bayes_pls_golite062009 |
| cytokine binding | 0.17817111033393 | bayes_pls_golite062009 |
| epidermal growth factor receptor activity | 0.160217511793891 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 0.150740450460731 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.148194101970458 | bayes_pls_golite062009 |
| transcription factor activity | 0.140216630442397 | bayes_pls_golite062009 |
| transcription activator activity | 0.088753929713159 | bayes_pls_golite062009 |
| receptor serine/threonine kinase binding | 0.0123645889643007 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
| SH2 domain binding | 2.96656737540424E-4 | bayes_pls_golite062009 |
