| Protein: | CHL1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 861 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CHL1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..861] | [1..861] |
|
|
0.0 | [10..860] | [13..906] |
|
|
0.0 | [5..857] | [8..841] |
|
Region A: Residues: [1-75] |
1 11 21 31 41 51
| | | | | |
1 MDKKEYSETF YHPYKPYDIQ VQLMETVYRV LSEGKKIAIL ESPTGTGKTL SLICATMTWL 60
61 RMNKADIFTR METNI
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.532 | 0.844 | DNA helicase activity | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.627 | 0.002 | chromosome segregation | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.711 | 0.002 | chromosome segregation | d.68.3 | SirA-like |
| View | Download | 0.763 | 0.001 | chromosome segregation | c.13.2 | Anti-sigma factor antagonist SpoIIaa |
| View | Download | 0.635 | N/A | N/A | c.114.1 | YchN-like |
| View | Download | 0.525 | N/A | N/A | d.68.6 | DNA-binding protein Sso10b (AlbA) |
| View | Download | 0.524 | N/A | N/A | c.13.2 | Anti-sigma factor antagonist SpoIIaa |
| View | Download | 0.472 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.437 | N/A | N/A | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.407 | N/A | N/A | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.390 | N/A | N/A | a.50.1 | Anaphylotoxins (complement system) |
| View | Download | 0.371 | N/A | N/A | c.9.1 | Barstar (barnase inhibitor) |
| View | Download | 0.369 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.363 | N/A | N/A | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.361 | N/A | N/A | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.350 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.350 | N/A | N/A | a.64.2 | Bacteriocin AS-48 |
| View | Download | 0.349 | N/A | N/A | c.10.1 | RNI-like |
| View | Download | 0.336 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.330 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.329 | N/A | N/A | a.60.2 | RuvA domain 2-like |
| View | Download | 0.322 | N/A | N/A | d.68.1 | Translation initiation factor IF3, C-terminal domain |
| View | Download | 0.319 | N/A | N/A | d.68.3 | SirA-like |
| View | Download | 0.313 | N/A | N/A | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.311 | N/A | N/A | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.304 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.302 | N/A | N/A | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.290 | N/A | N/A | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.280 | N/A | N/A | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.277 | N/A | N/A | a.11.2 | Second domain of FERM |
| View | Download | 0.272 | N/A | N/A | a.70.1 | N-terminal domain of the delta subunit of the F1F0-ATP synthase |
| View | Download | 0.259 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.254 | N/A | N/A | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.246 | N/A | N/A | c.23.4 | Succinyl-CoA synthetase domains |
| View | Download | 0.246 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.231 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.224 | N/A | N/A | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.220 | N/A | N/A | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.218 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.216 | N/A | N/A | c.23.12 | Formate/glycerate dehydrogenase catalytic domain-like |
| View | Download | 0.214 | N/A | N/A | c.59.1 | MurD-like peptide ligases, peptide-binding domain |
| View | Download | 0.214 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.214 | N/A | N/A | d.79.2 | Tubulin/Dihydroxyacetone kinase C-terminal domain |
| View | Download | 0.214 | N/A | N/A | c.10.2 | L domain-like |
| View | Download | 0.208 | N/A | N/A | a.77.1 | DEATH domain |
| View | Download | 0.205 | N/A | N/A | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.204 | N/A | N/A | a.118.9 | ENTH/VHS domain |
| View | Download | 0.202 | N/A | N/A | c.10.1 | RNI-like |
|
Region A: Residues: [76-148] |
1 11 21 31 41 51
| | | | | |
1 KTNEDDSENL SDDEPDWVID TYRKSVLQEK VDLLNDYEKH LNEINTTSCK QLKTMCDLDK 60
61 EHGRYKSVDP LRK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.528 | a.74.1 | Cyclin-like |
| View | Download | 0.652 | a.30.1 | ROP protein |
| View | Download | 0.531 | a.60.3 | C-terminal domain of RNA polymerase alpha subunit |
| View | Download | 0.600 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.575 | a.2.2 | Ribosomal protein L29 (L29p) |
| View | Download | 0.523 | a.2.7 | tRNA-binding arm |
| View | Download | 0.506 | a.64.1 | Saposin |
| View | Download | 0.483 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.429 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.408 | a.2.7 | tRNA-binding arm |
| View | Download | 0.407 | a.7.7 | BAG domain |
| View | Download | 0.399 | g.53.1 | TAZ domain |
| View | Download | 0.377 | a.23.5 | Hemolysin expression modulating protein HHA |
| View | Download | 0.376 | a.4.1 | Homeodomain-like |
| View | Download | 0.361 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.347 | a.4.1 | Homeodomain-like |
| View | Download | 0.339 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.320 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.318 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.315 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.300 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.300 | a.11.1 | Acyl-CoA binding protein |
| View | Download | 0.294 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.283 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.276 | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.270 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.264 | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.259 | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.248 | a.118.1 | ARM repeat |
| View | Download | 0.240 | a.60.2 | RuvA domain 2-like |
| View | Download | 0.237 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.226 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.225 | a.58.1 | Chemotaxis receptor methyltransferase CheR, N-terminal domain |
| View | Download | 0.222 | a.5.2 | UBA-like |
| View | Download | 0.220 | a.4.1 | Homeodomain-like |
| View | Download | 0.217 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.213 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.211 | a.74.1 | Cyclin-like |
| View | Download | 0.206 | a.4.1 | Homeodomain-like |
| View | Download | 0.201 | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.200 | a.4.5 | "Winged helix" DNA-binding domain |
| Term | Confidence | Notes |
| general RNA polymerase II transcription factor activity | 5.47805400577115 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 2.72462789867829 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 2.72222787956584 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| endodeoxyribonuclease activity | 2.60873257753475 | bayes_pls_golite062009 |
| hydrolase activity | 2.55157966585974 | bayes_pls_golite062009 |
| nucleic acid binding | 2.51683451033161 | bayes_pls_golite062009 |
| dATP binding | 2.44149059794577 | bayes_pls_golite062009 |
| DNA helicase activity | 2.2817164193758 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.13284212711072 | bayes_pls_golite062009 |
| DNA binding | 2.12258000781149 | bayes_pls_golite062009 |
| transcription regulator activity | 2.09345198747025 | bayes_pls_golite062009 |
| endonuclease activity | 1.96689197136388 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 1.88455339138556 | bayes_pls_golite062009 |
| helicase activity | 1.70242731830224 | bayes_pls_golite062009 |
| microtubule motor activity | 1.6537049553461 | bayes_pls_golite062009 |
| RNA helicase activity | 1.63960194106079 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 1.61735400124552 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 1.60404584546501 | bayes_pls_golite062009 |
| double-strand/single-strand DNA junction binding | 1.47358115221023 | bayes_pls_golite062009 |
| purine deoxyribonucleotide binding | 1.4428455823518 | bayes_pls_golite062009 |
| adenyl deoxyribonucleotide binding | 1.4428455823518 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 1.29640539057136 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.2539059700735 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| motor activity | 1.14667913749579 | bayes_pls_golite062009 |
| DNA clamp loader activity | 1.12431517057397 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.117585097627 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| transcription factor activity | 0.887108427603557 | bayes_pls_golite062009 |
| transcription repressor activity | 0.862685397469217 | bayes_pls_golite062009 |
| single-stranded DNA binding | 0.568457189190858 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.500462538667228 | bayes_pls_golite062009 |
| histone acetyltransferase activity | 0.328186246219424 | bayes_pls_golite062009 |
| lysine N-acetyltransferase activity | 0.328186246219424 | bayes_pls_golite062009 |
| mismatched DNA binding | 0.31144582840038 | bayes_pls_golite062009 |
| DNA strand annealing activity | 0.283577486331079 | bayes_pls_golite062009 |
| four-way junction helicase activity | 0.26252931460003 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.243902356228423 | bayes_pls_golite062009 |
| exodeoxyribonuclease V activity | 0.185603938981231 | bayes_pls_golite062009 |
| nucleotidyltransferase activity | 0.181509771587324 | bayes_pls_golite062009 |
| protein binding | 0.170837278876362 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.147579541298736 | bayes_pls_golite062009 |
| nucleotide binding | 0.114848452385726 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.113504049290503 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.111293884322157 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.10713474095071 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.0916519414118148 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.0915913646217636 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.089234257580272 | bayes_pls_golite062009 |
| 3'-5' DNA helicase activity | 0.0769112340058804 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K9 specific) | 0.0642842984371965 | bayes_pls_golite062009 |
| actin binding | 0.00482938540552702 | bayes_pls_golite062009 |
|
Region A: Residues: [149-263] |
1 11 21 31 41 51
| | | | | |
1 KRKGARHLDV SLEEQDFIPR PYESDSENND TSKSTRGGRI SDKDYKLSEL NSQIITLLDK 60
61 IDGKVSRDPN NGDRFDVTNQ NPVKIYYASR TYSQLGQFTS QLRLPSFPSS FRDKV
|
| Detection Method: | |
| Confidence: | 3.522879 |
| Match: | 1hv8A_ |
| Description: | Putative DEAD box RNA helicase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [264-410] |
1 11 21 31 41 51
| | | | | |
1 PDEKVKYLPL ASKKQLCINP KVMKWKTLEA INDACADLRH SKEGCIFYQN TNEWRHCPDT 60
61 LALRDMIFSE IQDIEDLVPL GKSLGICPYY ASREALPIAE VVTLPYQYLL SESTRSSLQI 120
121 NLENSIVIID EAHNLIETIN SIYSSQI
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.207 | c.23.1 | CheY-like |
| View | Download | 0.236 | c.78.1 | Aspartate/ornithine carbamoyltransferase |
| View | Download | 0.373 | c.1.17 | Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain |
| View | Download | 0.211 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.200 | a.96.1 | DNA-glycosylase |
|
Region A: Residues: [411-861] |
1 11 21 31 41 51
| | | | | |
1 SLEDLKNCHK GIVTYFNKFK SRLNPGNRVN LLKLNSLLMT LIQFIVKNFK KIGQEIDPND 60
61 MFTGSNIDTL NIHKLLRYIK VSKIAYKIDT YNQALKEEES SKNENPIKET HKKSVSSQPL 120
121 LFKVSQFLYC LTNLTSEGQF FFEKNYSIKY MLLEPSKPFE SILNQAKCVV LAGGTMEPMS 180
181 EFLSNLLPEV PSEDITTLSC NHVIPKENLQ TYITNQPELE FTFEKRMSPS LVNNHLFQFF 240
241 VDLSKAVPKK GGIVAFFPSY QYLAHVIQCW KQNDRFATLN NVRKIFYEAK DGDDILSGYS 300
301 DSVAEGRGSL LLAIVGGKLS EGINFQDDLC RAVVMVGLPF PNIFSGELIV KRKHLAAKIM 360
361 KSGGTEEEAS RATKEFMENI CMKAVNQSVG RAIRHANDYA NIYLLDVRYN RPNFRKKLSR 420
421 WVQDSINSEH TTHQVISSTR KFFSMRSLNS R
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
