| Protein: | PSK2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1101 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PSK2.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1101] | [1..1101] |
|
|
0.0 | [676..1100] | [154..598] |
|
|
0.0 | [676..1100] | [154..598] |
|
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0.0 | [676..1100] | [154..598] |
|
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0.0 | [676..1100] | [154..598] |
|
|
0.0 | [676..1100] | [154..598] |
|
|
0.0 | [676..1100] | [154..598] |
|
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0.0 | [675..1100] | [137..579] |
|
Region A: Residues: [1-208] |
1 11 21 31 41 51
| | | | | |
1 MTYPVSAAAP ADISYSKNTP LVGLSKPPCL YQHASSSVDS FSSTFSDDDR SDLVAVPNES 60
61 PHAFSYNPIS PNSLGVRLTI LRRSLEIMVN SPDILHELKK KAPVIAYPPS LRHTRNLTET 120
121 ATLSASRDPL NGSLISPLVS NMPSPASRPV IQRATSLMVL PDNDTASKLN PAKSELENLL 180
181 FLLNLALENN SFERASDLHM LSLLNIKK
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [209-287] |
1 11 21 31 41 51
| | | | | |
1 INFDSDIQKS ETLKKVLLDS LAEPFFENYK KFPHKDLGSK SQYNEYEEKH DDIVSLADIK 60
61 PQQDYSRILH PFTSAKNSG
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [288-433] |
1 11 21 31 41 51
| | | | | |
1 PEAIFTCSQQ YPWNFKAAND LACLTFGISK NVIKALTLLD LIHTDSRNFV LEKIMNAEDD 60
61 NQEIVFTGET IPIVQPNSTS NNNVPNLIWA SLWAKRKNGL LVCVFEKTPC DYIDVMLNLR 120
121 DFSVDSIIDT THFLENFDKK KQQEST
|
| Detection Method: | |
| Confidence: | 12.82 |
| Match: | 1ll8A |
| Description: | N-terminal PAS domain of Pas kinase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [434-627] |
1 11 21 31 41 51
| | | | | |
1 SPMTEKKTVK FANEIHDIGS VSHSLSKLID DVRFGKVFSA DDDLLPLSIR VANHVNEERY 60
61 FTLNCLSENI PCAVTTSVLE NEIKLKIHSL PYQAGLFIVD SHTLSLLSFN KSVAKNMFGL 120
121 RLHELAGSSV TKLVPSLADM ISYINKTYPM LNITLPENKG LVLTEHFFRK IEAEMHHDKD 180
181 SFYTSIGLDG CHKD
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| transcription regulator activity | 4.27604928641749 | bayes_pls_golite062009 |
| DNA binding | 3.83861939247274 | bayes_pls_golite062009 |
| nucleic acid binding | 3.43738039086015 | bayes_pls_golite062009 |
| transcription factor activity | 3.18442852449976 | bayes_pls_golite062009 |
| binding | 3.0194696248926 | bayes_pls_golite062009 |
| transcription factor binding | 2.22314179303094 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.13819142609078 | bayes_pls_golite062009 |
| transcription activator activity | 1.8593473738006 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.79890159148529 | bayes_pls_golite062009 |
| kinase activity | 1.74754238129423 | bayes_pls_golite062009 |
| protein kinase activity | 1.64278494326255 | bayes_pls_golite062009 |
| protein binding | 1.60673447924806 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.58952910634461 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.54935001412565 | bayes_pls_golite062009 |
| transporter activity | 1.29285553966065 | bayes_pls_golite062009 |
| transferase activity | 1.23751181381315 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.12976327507582 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.06445298547053 | bayes_pls_golite062009 |
| protein dimerization activity | 1.03821974317465 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.01758076208626 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.934727986222767 | bayes_pls_golite062009 |
| enzyme binding | 0.902069383016175 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.872276459885952 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.865848090169615 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 0.836285382533069 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.832216703182726 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.818533732821494 | bayes_pls_golite062009 |
| cation channel activity | 0.764382438962433 | bayes_pls_golite062009 |
| voltage-gated channel activity | 0.724783984982155 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 0.724434551854819 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 0.701205842109604 | bayes_pls_golite062009 |
| gated channel activity | 0.678642047604949 | bayes_pls_golite062009 |
| ion channel activity | 0.642071926991696 | bayes_pls_golite062009 |
| potassium channel activity | 0.634191734666345 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.614755150740891 | bayes_pls_golite062009 |
| histone acetyltransferase binding | 0.609670492126344 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.603095294300374 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.593195618191767 | bayes_pls_golite062009 |
| channel activity | 0.593195618191767 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 0.533026069704694 | bayes_pls_golite062009 |
| receptor binding | 0.47195382831751 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.119454387636252 | bayes_pls_golite062009 |
| transcription repressor activity | 0.104316215089923 | bayes_pls_golite062009 |
|
Region A: Residues: [628-813] |
1 11 21 31 41 51
| | | | | |
1 GNLIKVDVQL RVLNTNAVLL WITHSRDVVI ENYTTVPSQL PMLKENEIDV VGSRGSSSAS 60
61 SKKSSEKIPV NTLKAMADLS ISSAETISNS DDEVDLNQVN EKLRETSCGK VRGIESNDNN 120
121 NYDDDMTMVD DPELKHKIEL TKMYTQDKSK FVKDDNFKVD EKFIMRIIEP INGEEIKKET 180
181 NELDKR
|
| Detection Method: | |
| Confidence: | 23.0 |
| Match: | 1dsyA_ |
| Description: | C2 domain from protein kinase c (alpha) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.77482286467294 | bayes_pls_golite062009 |
| lipid binding | 1.47484095830847 | bayes_pls_golite062009 |
| protein binding | 1.33917246836907 | bayes_pls_golite062009 |
| phospholipid binding | 0.98776359922762 | bayes_pls_golite062009 |
| transporter activity | 0.698425581375283 | bayes_pls_golite062009 |
| calcium-dependent phospholipid binding | 0.688833750465289 | bayes_pls_golite062009 |
| profilin binding | 0.32399339703241 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.172018617171784 | bayes_pls_golite062009 |
| SNARE binding | 0.102282725391911 | bayes_pls_golite062009 |
|
Region A: Residues: [814-896] |
1 11 21 31 41 51
| | | | | |
1 NSTLKATYLT TPEANIGSQK RIKKFSDFTI LQVMGEGAYG KVNLCIHNRE HYIVVIKMIF 60
61 KERILVDTWV RDRKLGTIPS EIQ
|
|
Region B: Residues: [912-931] |
1 11 21 31 41 51
| | | | | |
1 LLDFFEDDDY YYIETPVHGE
|
| Detection Method: | |
| Confidence: | 318.228787 |
| Match: | 1fotA_ |
| Description: | cAMP-dependent PK, catalytic subunit |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [897-911] |
1 11 21 31 41 51
| | | | | |
1 IMATLNKNSQ ENILK
|
|
Region B: Residues: [932-1101] |
1 11 21 31 41 51
| | | | | |
1 TGSIDLFDVI EFKKDMVEHE AKLVFKQVVA SIKHLHDQGI VHRDIKDENV IVDSHGFVKL 60
61 IDFGSAAYIK SGPFDVFVGT MDYAAPEVLG GSSYKGKPQD IWALGVLLYT IIYKENPYYN 120
121 IDEILEGELR FDKSEHVSEE CISLIKRILT REVDKRPTID EIYEDKWLKI
|
| Detection Method: | |
| Confidence: | 318.228787 |
| Match: | 1fotA_ |
| Description: | cAMP-dependent PK, catalytic subunit |
| Matching Structure (courtesy of the PDB): |
|
