| Protein: | PSK2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1101 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PSK2.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..1101] | [1..1101] |
|
|
0.0 | [676..1100] | [154..598] |
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0.0 | [676..1100] | [154..598] |
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0.0 | [676..1100] | [154..598] |
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0.0 | [676..1100] | [154..598] |
|
|
0.0 | [676..1100] | [154..598] |
|
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0.0 | [676..1100] | [154..598] |
|
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0.0 | [675..1100] | [137..579] |
|
Region A: Residues: [1-208] |
1 11 21 31 41 51
| | | | | |
1 MTYPVSAAAP ADISYSKNTP LVGLSKPPCL YQHASSSVDS FSSTFSDDDR SDLVAVPNES 60
61 PHAFSYNPIS PNSLGVRLTI LRRSLEIMVN SPDILHELKK KAPVIAYPPS LRHTRNLTET 120
121 ATLSASRDPL NGSLISPLVS NMPSPASRPV IQRATSLMVL PDNDTASKLN PAKSELENLL 180
181 FLLNLALENN SFERASDLHM LSLLNIKK
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [209-287] |
1 11 21 31 41 51
| | | | | |
1 INFDSDIQKS ETLKKVLLDS LAEPFFENYK KFPHKDLGSK SQYNEYEEKH DDIVSLADIK 60
61 PQQDYSRILH PFTSAKNSG
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.368 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.444 | d.45.1 | ClpS-like |
| View | Download | 0.493 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.414 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.493 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.356 | a.38.1 | Helix-loop-helix DNA-binding domain |
| View | Download | 0.351 | a.36.1 | Signal peptide-binding domain |
| View | Download | 0.345 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.325 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.322 | a.159.1 | Protein serine/threonine phosphatase 2C, C-terminal domain |
| View | Download | 0.321 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.302 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.296 | a.4.1 | Homeodomain-like |
| View | Download | 0.270 | a.112.1 | Description not found. |
| View | Download | 0.266 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.256 | d.74.3 | RBP11-like subunits of RNA polymerase |
| View | Download | 0.254 | a.24.4 | Hemerythrin |
| View | Download | 0.254 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.252 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.252 | b.55.1 | PH domain-like |
| View | Download | 0.250 | a.4.1 | Homeodomain-like |
| View | Download | 0.238 | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.237 | c.47.2 | RNA 3'-terminal phosphate cyclase, RPTC, insert domain |
| View | Download | 0.236 | d.26.3 | Chitinase insertion domain |
| View | Download | 0.234 | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.222 | a.39.1 | EF-hand |
| View | Download | 0.221 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.215 | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.215 | a.77.1 | DEATH domain |
| View | Download | 0.204 | a.118.1 | ARM repeat |
| View | Download | 0.203 | c.47.1 | Thioredoxin-like |
|
Region A: Residues: [288-433] |
1 11 21 31 41 51
| | | | | |
1 PEAIFTCSQQ YPWNFKAAND LACLTFGISK NVIKALTLLD LIHTDSRNFV LEKIMNAEDD 60
61 NQEIVFTGET IPIVQPNSTS NNNVPNLIWA SLWAKRKNGL LVCVFEKTPC DYIDVMLNLR 120
121 DFSVDSIIDT THFLENFDKK KQQEST
|
| Detection Method: | |
| Confidence: | 12.82 |
| Match: | 1ll8A |
| Description: | N-terminal PAS domain of Pas kinase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [434-627] |
1 11 21 31 41 51
| | | | | |
1 SPMTEKKTVK FANEIHDIGS VSHSLSKLID DVRFGKVFSA DDDLLPLSIR VANHVNEERY 60
61 FTLNCLSENI PCAVTTSVLE NEIKLKIHSL PYQAGLFIVD SHTLSLLSFN KSVAKNMFGL 120
121 RLHELAGSSV TKLVPSLADM ISYINKTYPM LNITLPENKG LVLTEHFFRK IEAEMHHDKD 180
181 SFYTSIGLDG CHKD
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| transcription regulator activity | 4.27604928641749 | bayes_pls_golite062009 |
| DNA binding | 3.83861939247274 | bayes_pls_golite062009 |
| nucleic acid binding | 3.43738039086015 | bayes_pls_golite062009 |
| transcription factor activity | 3.18442852449976 | bayes_pls_golite062009 |
| binding | 3.0194696248926 | bayes_pls_golite062009 |
| transcription factor binding | 2.22314179303094 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.13819142609078 | bayes_pls_golite062009 |
| transcription activator activity | 1.8593473738006 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.79890159148529 | bayes_pls_golite062009 |
| kinase activity | 1.74754238129423 | bayes_pls_golite062009 |
| protein kinase activity | 1.64278494326255 | bayes_pls_golite062009 |
| protein binding | 1.60673447924806 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.58952910634461 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.54935001412565 | bayes_pls_golite062009 |
| transporter activity | 1.29285553966065 | bayes_pls_golite062009 |
| transferase activity | 1.23751181381315 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.12976327507582 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.06445298547053 | bayes_pls_golite062009 |
| protein dimerization activity | 1.03821974317465 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.01758076208626 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.934727986222767 | bayes_pls_golite062009 |
| enzyme binding | 0.902069383016175 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.872276459885952 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.865848090169615 | bayes_pls_golite062009 |
| voltage-gated cation channel activity | 0.836285382533069 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.832216703182726 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.818533732821494 | bayes_pls_golite062009 |
| cation channel activity | 0.764382438962433 | bayes_pls_golite062009 |
| voltage-gated channel activity | 0.724783984982155 | bayes_pls_golite062009 |
| voltage-gated ion channel activity | 0.724434551854819 | bayes_pls_golite062009 |
| voltage-gated potassium channel activity | 0.701205842109604 | bayes_pls_golite062009 |
| gated channel activity | 0.678642047604949 | bayes_pls_golite062009 |
| ion channel activity | 0.642071926991696 | bayes_pls_golite062009 |
| potassium channel activity | 0.634191734666345 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity, enhancer binding | 0.614755150740891 | bayes_pls_golite062009 |
| histone acetyltransferase binding | 0.609670492126344 | bayes_pls_golite062009 |
| substrate-specific channel activity | 0.603095294300374 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 0.593195618191767 | bayes_pls_golite062009 |
| channel activity | 0.593195618191767 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 0.533026069704694 | bayes_pls_golite062009 |
| receptor binding | 0.47195382831751 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 0.119454387636252 | bayes_pls_golite062009 |
| transcription repressor activity | 0.104316215089923 | bayes_pls_golite062009 |
|
Region A: Residues: [628-813] |
1 11 21 31 41 51
| | | | | |
1 GNLIKVDVQL RVLNTNAVLL WITHSRDVVI ENYTTVPSQL PMLKENEIDV VGSRGSSSAS 60
61 SKKSSEKIPV NTLKAMADLS ISSAETISNS DDEVDLNQVN EKLRETSCGK VRGIESNDNN 120
121 NYDDDMTMVD DPELKHKIEL TKMYTQDKSK FVKDDNFKVD EKFIMRIIEP INGEEIKKET 180
181 NELDKR
|
| Detection Method: | |
| Confidence: | 23.0 |
| Match: | 1dsyA_ |
| Description: | C2 domain from protein kinase c (alpha) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.77482286467294 | bayes_pls_golite062009 |
| lipid binding | 1.47484095830847 | bayes_pls_golite062009 |
| protein binding | 1.33917246836907 | bayes_pls_golite062009 |
| phospholipid binding | 0.98776359922762 | bayes_pls_golite062009 |
| transporter activity | 0.698425581375283 | bayes_pls_golite062009 |
| calcium-dependent phospholipid binding | 0.688833750465289 | bayes_pls_golite062009 |
| profilin binding | 0.32399339703241 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.172018617171784 | bayes_pls_golite062009 |
| SNARE binding | 0.102282725391911 | bayes_pls_golite062009 |
|
Region A: Residues: [814-896] |
1 11 21 31 41 51
| | | | | |
1 NSTLKATYLT TPEANIGSQK RIKKFSDFTI LQVMGEGAYG KVNLCIHNRE HYIVVIKMIF 60
61 KERILVDTWV RDRKLGTIPS EIQ
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|
Region B: Residues: [912-931] |
1 11 21 31 41 51
| | | | | |
1 LLDFFEDDDY YYIETPVHGE
|
| Detection Method: | |
| Confidence: | 318.228787 |
| Match: | 1fotA_ |
| Description: | cAMP-dependent PK, catalytic subunit |
Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [897-911] |
1 11 21 31 41 51
| | | | | |
1 IMATLNKNSQ ENILK
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Region B: Residues: [932-1101] |
1 11 21 31 41 51
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1 TGSIDLFDVI EFKKDMVEHE AKLVFKQVVA SIKHLHDQGI VHRDIKDENV IVDSHGFVKL 60
61 IDFGSAAYIK SGPFDVFVGT MDYAAPEVLG GSSYKGKPQD IWALGVLLYT IIYKENPYYN 120
121 IDEILEGELR FDKSEHVSEE CISLIKRILT REVDKRPTID EIYEDKWLKI
|
| Detection Method: | |
| Confidence: | 318.228787 |
| Match: | 1fotA_ |
| Description: | cAMP-dependent PK, catalytic subunit |
| Matching Structure (courtesy of the PDB): |
|
