| Protein: | TPK1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 397 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPK1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..397] | [1..397] |
|
|
0.0 | [1..397] | [3..399] |
|
|
0.0 | [2..397] | [26..421] |
|
|
0.0 | [4..397] | [78..472] |
|
|
0.0 | [1..397] | [132..540] |
|
|
0.0 | [2..397] | [746..1150] |
|
Region A: Residues: [1-60] |
1 11 21 31 41 51
| | | | | |
1 MSTEEQNGGG QKSLDDRQGE ESQKGETSER ETTATESGNE SKSVEKEGGE TQEKPKQPHV 60
61
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.253 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| cyclic nucleotide-dependent protein kinase activity | 4.97855712164511 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| cAMP-dependent protein kinase activity | 4.66277812893755 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 2.54265774272269 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 2.16831387024372 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| tau-protein kinase activity | 2.00481226596005 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
| actin binding | 1.87817875565699 | bayes_pls_golite062009 |
| acetylcholine receptor activator activity | 1.83545227594542 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.82515074380651 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| JUN kinase kinase kinase kinase activity | 1.55257528159541 | bayes_pls_golite062009 |
| DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.32254739984688 | bayes_pls_golite062009 |
| gamma-tubulin binding | 1.28511591054866 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 1.25765701903393 | bayes_pls_golite062009 |
| protein binding | 1.22565748038754 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| nucleic acid binding | 1.16049201286103 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 1.02996109010965 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.959360414036299 | bayes_pls_golite062009 |
| growth factor binding | 0.86076618871384 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| actin filament binding | 0.794152600084 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.450699332958421 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| insulin receptor binding | 0.266450215230107 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| insulin receptor activity | 0.237134032032089 | bayes_pls_golite062009 |
| SH2 domain binding | 0.226760162354251 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 0.20643152368029 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 0.20643152368029 | bayes_pls_golite062009 |
| receptor binding | 0.197402253061255 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.148194101970458 | bayes_pls_golite062009 |
| peptide binding | 0.118578378753757 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| MAP kinase kinase kinase kinase activity | 0.01826424351081 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
|
Region A: Residues: [61-136] |
1 11 21 31 41 51
| | | | | |
1 TYYNEEQYKQ FIAQARVTVG SIVYKNFQIL RTLGTGSFGR VHLIRSRHNG RYYAMKVLKK 60
61 EIVVRLKQVE HTNDER
|
|
Region B: Residues: [150-166] |
1 11 21 31 41 51
| | | | | |
1 MWGTFQDAQQ IFMIMDY
|
|
Region C: Residues: [362-397] |
1 11 21 31 41 51
| | | | | |
1 IQQGQGDTSQ FDKYPEEDIN YGVQGEDPYA DLFRDF
|
| Detection Method: | |
| Confidence: | 10140.0 |
| Match: | 1fotA_ |
| Description: | cAMP-dependent PK, catalytic subunit |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [137-149] |
1 11 21 31 41 51
| | | | | |
1 LMLSIVTHPF IIR
|
|
Region B: Residues: [167-361] |
1 11 21 31 41 51
| | | | | |
1 IEGGELFSLL RKSQRFPNPV AKFYAAEVCL ALEYLHSKDI IYRDLKPENI LLDKNGHIKI 60
61 TDFGFAKYVP DVTYTLCGTP DYIAPEVVST KPYNKSIDWW SFGILIYEML AGYTPFYDSN 120
121 TMKTYEKILN AELRFPPFFN EDVKDLLSRL ITRDLSQRLG NLQNGTEDVK NHPWFKEVVW 180
181 EKLLSRNIET PYEPP
|
| Detection Method: | |
| Confidence: | 10140.0 |
| Match: | 1fotA_ |
| Description: | cAMP-dependent PK, catalytic subunit |
| Matching Structure (courtesy of the PDB): |
|
