| Protein: | PTK2_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 818 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTK2_YEAST.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..818] | [1..818] |
|
|
0.0 | [126..760] | [1..569] |
|
|
0.0 | [126..760] | [1..569] |
|
|
0.0 | [126..760] | [1..572] |
|
|
0.0 | [185..755] | [3..526] |
|
|
0.0 | [168..748] | [6..538] |
|
Region A: Residues: [1-225] |
1 11 21 31 41 51
| | | | | |
1 MAGNGKDKEV DKSPSVSTLK LLGKRLFNSS SHTDNSSLLL SAEQLGNGRS LRKRPTSPSI 60
61 SGSGSGGNSP SSSAGARQRS ASLHRRKNNA SVGFSNGSVS SHKSSVALQD LIKHNNNPYL 120
121 NSPSDILGTG TGIASTRDRD RAVLDREKEK ERARNKERNT HHAGLPQRSN SMASHHFPNE 180
181 NIVYNPYGIS PNHARPDTAF ADTLNTNKEN DLSFYMHDGN SKIRM
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| acetylcholine receptor activator activity | 5.9159846946654 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 1.94085498993561 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| actin binding | 1.87817875565699 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 1.74206248731815 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| growth factor binding | 1.53863828216563 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 1.34841233233438 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 1.33825339298024 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.25285260301349 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 1.24312972088703 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 1.2266791546014 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine kinase activity | 1.11664317075762 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 1.10045286406485 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 1.10045286406485 | bayes_pls_golite062009 |
| vinculin binding | 1.06656350652527 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 0.98689034826741 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.959360414036299 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| actin filament binding | 0.794152600084 | bayes_pls_golite062009 |
| nucleic acid binding | 0.794058505655489 | bayes_pls_golite062009 |
| transcription regulator activity | 0.775404673285876 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.75189004129952 | bayes_pls_golite062009 |
| DNA binding | 0.714163549867672 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| transcription repressor activity | 0.568332175782799 | bayes_pls_golite062009 |
| transcription factor activity | 0.563262875317016 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.51726292539973 | bayes_pls_golite062009 |
| activin binding | 0.510364757301021 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.450699332958421 | bayes_pls_golite062009 |
| structural constituent of muscle | 0.399773397398032 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| tubulin binding | 0.385009627613955 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| phosphotyrosine binding | 0.311079584914389 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| insulin receptor activity | 0.188254408239569 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.148194101970458 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
| brain-derived neurotrophic factor binding | 0.00315481858218991 | bayes_pls_golite062009 |
|
Region A: Residues: [226-343] |
1 11 21 31 41 51
| | | | | |
1 LPLPIANPND FLPEDMKQYS VHLTDNFVFD TDNKPIGSGG SSEVRKVKSS YRQKDVYALK 60
61 KLNMIYHESP EKFYKRCSKE FIIAKHLSHN VHITNTFYLL KVPTTTYTTR GWGFIMEL
|
| Detection Method: | |
| Confidence: | 256.9897 |
| Match: | 1aq1__ |
| Description: | Cyclin-dependent PK, CDK2 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [344-424] |
1 11 21 31 41 51
| | | | | |
1 GVKDLFQLME RTGWKNVPFN EKYCLFKQVA QGIKFCHDNG IAHRDLKPEN VLISKEGICK 60
61 LTDFGISDWY HVIPHDYTSP V
|
|
Region B: Residues: [564-584] |
1 11 21 31 41 51
| | | | | |
1 QIETCVEPND DDLVRVPELR K
|
| Detection Method: | |
| Confidence: | 256.9897 |
| Match: | 1aq1__ |
| Description: | Cyclin-dependent PK, CDK2 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [425-493] |
1 11 21 31 41 51
| | | | | |
1 KTCQGMIGSP PYTPPEVMYF DAKKHYPEKF QKPYNPLAMD SYALGIMLIT MINNIIPFID 60
61 SCNTDARFR
|
| Detection Method: | |
| Confidence: | 256.9897 |
| Match: | 1aq1__ |
| Description: | Cyclin-dependent PK, CDK2 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [494-563] |
1 11 21 31 41 51
| | | | | |
1 EFEVSYDNFI NHQNPHFRDK GCHKPGPGSE YSLARNFKNT DATRIAWRLA DPNPATRYTM 60
61 DDLFNDPFFQ
|
| Detection Method: | |
| Confidence: | 256.9897 |
| Match: | 1aq1__ |
| Description: | Cyclin-dependent PK, CDK2 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [585-671] |
1 11 21 31 41 51
| | | | | |
1 STSTNDFSEN SLDAPHDQEV IHTSNPFLKK ETLTSKPRSM LEIAESPSLK QKSKVKDSAK 60
61 TKTHDVGDEG GNESTKPKQQ DKKENLK
|
| Detection Method: | |
| Confidence: | 22.0 |
| Match: | 1a29__ |
| Description: | Calmodulin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [672-760] |
1 11 21 31 41 51
| | | | | |
1 KDEVKNGDKD KVIEEATTTN VDSILEKPTP TSTKVEDNLS EDDSTMKELK SMLNSTPTTP 60
61 THNGPTPLPA KAGTQLDKRM SDLSLKSET
|
| Detection Method: | |
| Confidence: | 22.0 |
| Match: | 1a29__ |
| Description: | Calmodulin |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [761-818] |
1 11 21 31 41 51
| | | | | |
1 PASTKNFSAP NVSSSSNSLR SLGSPSVSSS KKKKVIHHHL DITNSVTNMS SVSAFISR
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
