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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.672166261694]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

cytoplasmic microtubule 4.5979E-6 2 14 2 6292
microtubule 2.3495E-5 2 31 2 6292
microtubule organizing center 9.8679E-5 2 63 2 6292
spindle pole body 9.8679E-5 2 63 2 6292
spindle pole 1.151E-4 2 68 2 6292
spindle 1.9786E-4 2 89 2 6292
microtubule cytoskeleton 2.8118E-4 2 106 2 6292
cytoskeletal part 1.0156E-3 2 201 2 6292
cytoskeleton 1.1732E-3 2 216 2 6292
kinesin complex 2.224E-3 2 7 1 6292
microtubule associated complex 5.7138E-3 2 18 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

establishment of organelle localization 7.5032E-5 2 55 2 6292
mitotic sister chromatid segregation 1.0838E-4 2 66 2 6292
sister chromatid segregation 1.1854E-4 2 69 2 6292
organelle localization 1.8038E-4 2 85 2 6292
microtubule cytoskeleton organization 2.3525E-4 2 97 2 6292
mitosis 2.7062E-4 2 104 2 6292
nuclear division 2.8118E-4 2 106 2 6292
microtubule-based process 3.0847E-4 2 111 2 6292
organelle fission 3.1973E-4 2 113 2 6292
chromosome segregation 4.1068E-4 2 128 2 6292
M phase of mitotic cell cycle 4.1068E-4 2 128 2 6292
cytoskeleton organization 1.3422E-3 2 231 2 6292
negative regulation of microtubule polymerization or depolymerization 1.5888E-3 2 5 1 6292
regulation of microtubule depolymerization 1.5888E-3 2 5 1 6292
negative regulation of microtubule depolymerization 1.5888E-3 2 5 1 6292
mitotic cell cycle 1.6363E-3 2 255 2 6292
microtubule depolymerization 1.9064E-3 2 6 1 6292
M phase 2.1762E-3 2 294 2 6292
negative regulation of protein complex disassembly 2.224E-3 2 7 1 6292
negative regulation of cytoskeleton organization 2.5415E-3 2 8 1 6292
establishment of mitotic spindle localization 3.1764E-3 2 10 1 6292
protein depolymerization 3.1764E-3 2 10 1 6292
spindle localization 3.1764E-3 2 10 1 6292
regulation of protein complex disassembly 3.1764E-3 2 10 1 6292
establishment of spindle localization 3.1764E-3 2 10 1 6292
establishment of spindle orientation 3.1764E-3 2 10 1 6292
establishment of mitotic spindle orientation 3.1764E-3 2 10 1 6292
cell cycle phase 3.5621E-3 2 376 2 6292
microtubule-based movement 5.0798E-3 2 16 1 6292
nuclear migration along microtubule 5.0798E-3 2 16 1 6292
microtubule-based transport 5.0798E-3 2 16 1 6292
regulation of microtubule polymerization or depolymerization 5.3968E-3 2 17 1 6292
regulation of microtubule cytoskeleton organization 5.3968E-3 2 17 1 6292
regulation of microtubule-based process 5.3968E-3 2 17 1 6292
cytoskeleton-dependent intracellular transport 5.7138E-3 2 18 1 6292
karyogamy involved in conjugation with cellular fusion 5.7138E-3 2 18 1 6292
karyogamy 5.7138E-3 2 18 1 6292
microtubule polymerization or depolymerization 5.7138E-3 2 18 1 6292
cell cycle process 6.0534E-3 2 490 2 6292
nuclear migration 6.3477E-3 2 20 1 6292
nucleus localization 6.3477E-3 2 20 1 6292
regulation of cytoskeleton organization 6.3477E-3 2 20 1 6292
establishment of nucleus localization 6.3477E-3 2 20 1 6292
mitotic cell cycle spindle assembly checkpoint 6.6645E-3 2 21 1 6292
negative regulation of nuclear division 6.6645E-3 2 21 1 6292
negative regulation of mitosis 6.6645E-3 2 21 1 6292
negative regulation of mitotic metaphase/anaphase transition 6.6645E-3 2 21 1 6292
spindle assembly checkpoint 6.6645E-3 2 21 1 6292
cell cycle 6.95E-3 2 525 2 6292
negative regulation of cell cycle 6.9813E-3 2 22 1 6292
microtubule nucleation 7.2981E-3 2 23 1 6292
mitotic sister chromatid cohesion 7.2981E-3 2 23 1 6292
chromosome organization 7.7677E-3 2 555 2 6292
spindle checkpoint 7.9314E-3 2 25 1 6292
regulation of mitotic metaphase/anaphase transition 7.9314E-3 2 25 1 6292
mitotic cell cycle spindle checkpoint 7.9314E-3 2 25 1 6292
mitotic spindle organization in nucleus 8.248E-3 2 26 1 6292
mitotic cell cycle checkpoint 8.8811E-3 2 28 1 6292
establishment of localization in cell 9.0494E-3 2 599 2 6292
negative regulation of cellular component organization 9.1975E-3 2 29 1 6292
regulation of nuclear division 9.1975E-3 2 29 1 6292
negative regulation of organelle organization 9.1975E-3 2 29 1 6292
regulation of mitosis 9.1975E-3 2 29 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

microtubule motor activity 3.1764E-3 2 10 1 6292
motor activity 5.7138E-3 2 18 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle