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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.29064665617]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
TAF13
  • nucleus
  • transcription factor TFIID complex
    		•
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
    		•
  • general RNA polymerase II transcription factor activity
    		•
    TAF6
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
    		•
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
    		•
  • general RNA polymerase II transcription factor activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription factor TFIID complex 5.3053E-6 2 15 2 6292
    DNA-directed RNA polymerase II, holoenzyme 7.7811E-5 2 56 2 6292
    transcription factor complex 1.2556E-4 2 71 2 6292
    nucleoplasm part 1.5102E-3 2 245 2 6292
    nucleoplasm 1.7541E-3 2 264 2 6292
    SLIK (SAGA-like) complex 5.0798E-3 2 16 1 6292
    nuclear lumen 5.1728E-3 2 453 2 6292
    SAGA complex 6.9813E-3 2 22 1 6292
    SAGA-type complex 7.2981E-3 2 23 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    regulation of transcription involved in G1 phase of mitotic cell cycle 4.5979E-6 2 14 2 6292
    G1 phase of mitotic cell cycle 1.7735E-5 2 27 2 6292
    G1 phase 1.7735E-5 2 27 2 6292
    transcription initiation from RNA polymerase II promoter 5.4619E-5 2 47 2 6292
    transcription initiation 8.3521E-5 2 58 2 6292
    interphase of mitotic cell cycle 2.3525E-4 2 97 2 6292
    interphase 2.3525E-4 2 97 2 6292
    protein complex biogenesis 6.0304E-4 2 155 2 6292
    protein complex assembly 6.0304E-4 2 155 2 6292
    regulation of transcription from RNA polymerase II promoter 1.3075E-3 2 228 2 6292
    mitotic cell cycle 1.6363E-3 2 255 2 6292
    macromolecular complex assembly 1.9877E-3 2 281 2 6292
    transcription from RNA polymerase II promoter 2.8267E-3 2 335 2 6292
    macromolecular complex subunit organization 3.2108E-3 2 357 2 6292
    regulation of transcription, DNA-dependent 3.2288E-3 2 358 2 6292
    regulation of RNA metabolic process 3.3198E-3 2 363 2 6292
    cell cycle phase 3.5621E-3 2 376 2 6292
    regulation of transcription 3.7155E-3 2 384 2 6292
    cellular component assembly 3.7349E-3 2 385 2 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.3405E-3 2 415 2 6292
    regulation of nitrogen compound metabolic process 4.3615E-3 2 416 2 6292
    regulation of gene expression 4.9915E-3 2 445 2 6292
    regulation of macromolecule biosynthetic process 5.2416E-3 2 456 2 6292
    regulation of cellular biosynthetic process 5.6164E-3 2 472 2 6292
    regulation of biosynthetic process 5.6402E-3 2 473 2 6292
    regulation of macromolecule metabolic process 6.004E-3 2 488 2 6292
    cell cycle process 6.0534E-3 2 490 2 6292
    transcription, DNA-dependent 6.3792E-3 2 503 2 6292
    RNA biosynthetic process 6.5067E-3 2 508 2 6292
    regulation of primary metabolic process 6.6615E-3 2 514 2 6292
    cell cycle 6.95E-3 2 525 2 6292
    regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
    regulation of metabolic process 7.5452E-3 2 547 2 6292
    transcription 7.6839E-3 2 552 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    general RNA polymerase II transcription factor activity 1.0186E-4 2 64 2 6292
    RNA polymerase II transcription factor activity 4.2367E-4 2 130 2 6292
    transcription regulator activity 2.8947E-3 2 339 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle