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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.87730201332]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA polymerase complex 2.2737E-6 2 10 2 6292
nuclear replisome 7.7306E-6 2 18 2 6292
replisome 7.7306E-6 2 18 2 6292
nuclear replication fork 9.6001E-6 2 20 2 6292
replication fork 4.3504E-5 2 42 2 6292
protein-DNA complex 8.0641E-5 2 57 2 6292
nuclear chromosome part 9.0721E-4 2 190 2 6292
delta DNA polymerase complex 9.5344E-4 2 3 1 6292
nuclear chromosome 1.3075E-3 2 228 2 6292
chromosomal part 1.413E-3 2 237 2 6292
epsilon DNA polymerase complex 1.5888E-3 2 5 1 6292
chromosome 1.8898E-3 2 274 2 6292
nucleotide-excision repair complex 6.6645E-3 2 21 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

leading strand elongation 5.3053E-6 2 15 2 6292
lagging strand elongation 7.7306E-6 2 18 2 6292
mismatch repair 1.7735E-5 2 27 2 6292
DNA strand elongation 2.3495E-5 2 31 2 6292
DNA strand elongation involved in DNA replication 2.3495E-5 2 31 2 6292
nucleotide-excision repair 3.552E-5 2 38 2 6292
DNA-dependent DNA replication 1.678E-4 2 82 2 6292
DNA replication 3.791E-4 2 123 2 6292
DNA repair 9.2646E-4 2 192 2 6292
DNA synthesis involved in DNA repair 1.2712E-3 2 4 1 6292
response to DNA damage stimulus 1.4011E-3 2 236 2 6292
cellular response to stress 2.1173E-3 2 290 2 6292
mutagenesis 2.859E-3 2 9 1 6292
cellular response to stimulus 3.6193E-3 2 379 2 6292
base-excision repair 3.811E-3 2 12 1 6292
postreplication repair 5.7138E-3 2 18 1 6292
response to stress 6.2277E-3 2 497 2 6292
DNA metabolic process 8.631E-3 2 585 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

single-stranded DNA specific exodeoxyribonuclease activity 9.5344E-4 2 3 1 6292
single-stranded DNA specific 3'-5' exodeoxyribonuclease activity 9.5344E-4 2 3 1 6292
3'-5'-exodeoxyribonuclease activity 1.9064E-3 2 6 1 6292
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 2.5415E-3 2 8 1 6292
zinc ion binding 2.5415E-3 2 8 1 6292
exodeoxyribonuclease activity 2.859E-3 2 9 1 6292
double-stranded DNA binding 7.2981E-3 2 23 1 6292
transition metal ion binding 7.6148E-3 2 24 1 6292
deoxyribonuclease activity 9.1975E-3 2 29 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle