From Publication: | Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3. |
Notes: | This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Arp2. The topolgies of protein complexes in this experiment are unknown. |
Complex Size: | 14 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
Arp2/3 protein complex | 4.4454E-20 | 14 | 7 | 7 | 6292 |
actin cytoskeleton | 2.0327E-10 | 14 | 85 | 7 | 6292 |
cytoskeletal part | 8.6859E-8 | 14 | 201 | 7 | 6292 |
cytoskeleton | 1.4267E-7 | 14 | 216 | 7 | 6292 |
protein complex | 1.7681E-5 | 14 | 1137 | 10 | 6292 |
non-membrane-bounded organelle | 3.6012E-4 | 14 | 959 | 8 | 6292 |
intracellular non-membrane-bounded organelle | 3.6012E-4 | 14 | 959 | 8 | 6292 |
macromolecular complex | 4.733E-4 | 14 | 1635 | 10 | 6292 |
external side of mitochondrial outer membrane | 2.225E-3 | 14 | 1 | 1 | 6292 |
mitochondrial proton-transporting ATP synthase, central stalk | 6.6614E-3 | 14 | 3 | 1 | 6292 |
proton-transporting ATP synthase, central stalk | 6.6614E-3 | 14 | 3 | 1 | 6292 |
intracellular organelle part | 7.9969E-3 | 14 | 2282 | 10 | 6292 |
organelle part | 7.9969E-3 | 14 | 2282 | 10 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
structural molecule activity | 3.0635E-6 | 14 | 339 | 7 | 6292 |
structural constituent of cytoskeleton | 4.2206E-6 | 14 | 53 | 4 | 6292 |
actin binding | 1.1394E-5 | 14 | 21 | 3 | 6292 |
cytoskeletal protein binding | 2.6493E-4 | 14 | 59 | 3 | 6292 |
ATP binding | 1.234E-3 | 14 | 24 | 2 | 6292 |
adenyl ribonucleotide binding | 1.3396E-3 | 14 | 25 | 2 | 6292 |
adenyl nucleotide binding | 1.9301E-3 | 14 | 30 | 2 | 6292 |
purine nucleoside binding | 2.0606E-3 | 14 | 31 | 2 | 6292 |
nucleoside binding | 2.1952E-3 | 14 | 32 | 2 | 6292 |
glutamine-fructose-6-phosphate transaminase (isomerizing) activity | 2.225E-3 | 14 | 1 | 1 | 6292 |
ribonucleotide binding | 3.5879E-3 | 14 | 41 | 2 | 6292 |
purine ribonucleotide binding | 3.5879E-3 | 14 | 41 | 2 | 6292 |
oxidoreductase activity, oxidizing metal ions, oxygen as acceptor | 4.4455E-3 | 14 | 2 | 1 | 6292 |
ferroxidase activity | 4.4455E-3 | 14 | 2 | 1 | 6292 |
purine nucleotide binding | 5.7214E-3 | 14 | 52 | 2 | 6292 |
nucleotide binding | 7.3172E-3 | 14 | 59 | 2 | 6292 |