YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

The actin nucleation process by which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins. The actin nucleation process by which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament. Any process that stops, prevents or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament. Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: actin nucleation
Acc: GO:0045010
Aspect: Biological Process
Desc: The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.
Synonyms:
  • actin filament nucleation
Proteins in PDR annotated with:
   This term: 34 [Search]
   Term or descendants: 58 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045010 - actin nucleation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle