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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Snf1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 7 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARF1
  • cytosol
  • Golgi-associated vesicle
  • ER to Golgi vesicle-mediated transport
  • Golgi to plasma membrane transport
  • telomere maintenance
  • intra-Golgi vesicle-mediated transport
  • GTPase activity
  • GAL83
  • nucleus
  • cytoplasm
  • nuclear envelope lumen
  • AMP-activated protein kinase complex
  • signal transduction
  • regulation of protein complex assembly
  • cell adhesion
  • invasive growth in response to glucose limitation
  • protein amino acid phosphorylation
  • AMP-activated protein kinase activity
  • GIS4
  • plasma membrane
  • cellular ion homeostasis
  • molecular_function
  • PRB1
  • fungal-type vacuole lumen
  • fungal-type vacuole
  • cellular response to starvation
  • sporulation resulting in formation of a cellular spore
  • vacuolar protein catabolic process
  • serine-type endopeptidase activity
  • SNF1
  • nucleus
  • cytoplasm
  • mitochondrion
  • fungal-type vacuole
  • nuclear envelope lumen
  • AMP-activated protein kinase complex
  • regulation of carbohydrate metabolic process
  • signal transduction
  • pseudohyphal growth
  • cell adhesion
  • invasive growth in response to glucose limitation
  • protein amino acid phosphorylation
  • replicative cell aging
  • biofilm formation
  • positive regulation of gluconeogenesis
  • cellular response to nitrogen starvation
  • AMP-activated protein kinase activity
  • SNF4
  • nucleus
  • cytoplasm
  • nuclear envelope lumen
  • plasma membrane
  • AMP-activated protein kinase complex
  • peroxisome organization
  • protein amino acid phosphorylation
  • replicative cell aging
  • positive regulation of gluconeogenesis
  • regulation of transcription from RNA polymerase II promoter
  • AMP-activated protein kinase activity
  • protein serine/threonine kinase activator activity
  • UBI4
  • cytoplasm
  • protein deubiquitination
  • ascospore formation
  • protein polyubiquitination
  • protein monoubiquitination
  • response to stress
  • protein ubiquitination
  • protein tag
  • ATP-dependent protein binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nuclear envelope lumen 3.3722E-9 7 4 3 6292
    AMP-activated protein kinase complex 1.6845E-8 7 6 3 6292
    organelle envelope lumen 8.1872E-6 7 40 3 6292
    nuclear envelope 9.9288E-4 7 199 3 6292
    membrane-enclosed lumen 4.0336E-3 7 700 4 6292
    endomembrane system 7.2588E-3 7 398 3 6292
    fungal-type vacuole lumen 7.7654E-3 7 7 1 6292
    vacuolar lumen 9.9746E-3 7 9 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    positive regulation of gluconeogenesis 6.3596E-6 7 4 2 6292
    biological adhesion 2.9615E-5 7 8 2 6292
    positive regulation of glucose metabolic process 2.9615E-5 7 8 2 6292
    cell adhesion 2.9615E-5 7 8 2 6292
    positive regulation of cellular carbohydrate metabolic process 2.9615E-5 7 8 2 6292
    positive regulation of carbohydrate metabolic process 2.9615E-5 7 8 2 6292
    regulation of gluconeogenesis 1.2639E-4 7 16 2 6292
    protein amino acid phosphorylation 1.4218E-4 7 103 3 6292
    regulation of cellular ketone metabolic process 1.6097E-4 7 18 2 6292
    developmental process 2.3199E-4 7 331 4 6292
    regulation of carbohydrate biosynthetic process 2.4252E-4 7 22 2 6292
    cellular response to starvation 2.4252E-4 7 22 2 6292
    response to starvation 2.4252E-4 7 22 2 6292
    post-translational protein modification 3.1112E-4 7 357 4 6292
    regulation of glucose metabolic process 4.2467E-4 7 29 2 6292
    regulation of cellular carbohydrate metabolic process 4.2467E-4 7 29 2 6292
    gluconeogenesis 5.511E-4 7 33 2 6292
    cellular response to external stimulus 6.2038E-4 7 35 2 6292
    hexose biosynthetic process 6.2038E-4 7 35 2 6292
    cellular response to extracellular stimulus 6.2038E-4 7 35 2 6292
    cellular response to nutrient levels 6.2038E-4 7 35 2 6292
    regulation of carbohydrate metabolic process 6.5652E-4 7 36 2 6292
    phosphorylation 7.2841E-4 7 179 3 6292
    replicative cell aging 7.3181E-4 7 38 2 6292
    monosaccharide biosynthetic process 7.3181E-4 7 38 2 6292
    response to extracellular stimulus 7.3181E-4 7 38 2 6292
    response to nutrient levels 7.3181E-4 7 38 2 6292
    response to external stimulus 7.3181E-4 7 38 2 6292
    pyruvate metabolic process 9.8164E-4 7 44 2 6292
    invasive growth in response to glucose limitation 1.1199E-3 7 47 2 6292
    alcohol biosynthetic process 1.1199E-3 7 47 2 6292
    protein modification process 1.1271E-3 7 499 4 6292
    cell communication 1.2171E-3 7 49 2 6292
    cell aging 1.2171E-3 7 49 2 6292
    aging 1.3181E-3 7 51 2 6292
    phosphorus metabolic process 1.4941E-3 7 229 3 6292
    phosphate metabolic process 1.4941E-3 7 229 3 6292
    macromolecule modification 1.8549E-3 7 569 4 6292
    cellular response to nitrogen levels 2.224E-3 7 2 1 6292
    cellular response to nitrogen starvation 2.224E-3 7 2 1 6292
    cellular protein metabolic process 2.2261E-3 7 1074 5 6292
    protein metabolic process 2.8929E-3 7 1136 5 6292
    cellular carbohydrate biosynthetic process 3.0603E-3 7 78 2 6292
    biological regulation 3.9225E-3 7 1213 5 6292
    filamentous growth of a population of unicellular organisms 4.0554E-3 7 90 2 6292
    growth of unicellular organism as a thread of attached cells 4.0554E-3 7 90 2 6292
    carbohydrate biosynthetic process 4.1444E-3 7 91 2 6292
    filamentous growth 5.5873E-3 7 106 2 6292
    glucose metabolic process 5.9001E-3 7 109 2 6292
    biofilm formation 6.6592E-3 7 6 1 6292
    positive regulation of biosynthetic process 7.231E-3 7 121 2 6292
    positive regulation of cellular biosynthetic process 7.231E-3 7 121 2 6292
    hexose metabolic process 7.5834E-3 7 124 2 6292
    sporulation 7.7026E-3 7 125 2 6292
    sporulation resulting in formation of a cellular spore 7.7026E-3 7 125 2 6292
    anatomical structure formation involved in morphogenesis 8.188E-3 7 129 2 6292
    positive regulation of metabolic process 8.188E-3 7 129 2 6292
    positive regulation of cellular metabolic process 8.188E-3 7 129 2 6292
    monocarboxylic acid metabolic process 8.814E-3 7 134 2 6292
    monosaccharide metabolic process 8.9418E-3 7 135 2 6292
    positive regulation of cellular process 9.0704E-3 7 136 2 6292
    positive regulation of biological process 9.1999E-3 7 137 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    AMP-activated protein kinase activity 1.6845E-8 7 6 3 6292
    protein serine/threonine kinase activity 9.8236E-5 7 91 3 6292
    protein kinase activity 4.8635E-4 7 156 3 6292
    phosphotransferase activity, alcohol group as acceptor 9.7839E-4 7 198 3 6292
    ATP-dependent protein binding 1.1125E-3 7 1 1 6292
    kinase activity 1.3653E-3 7 222 3 6292
    protein serine/threonine kinase activator activity 2.224E-3 7 2 1 6292
    serine-type endopeptidase activity 4.4437E-3 7 4 1 6292
    serine-type peptidase activity 6.6592E-3 7 6 1 6292
    transferase activity, transferring phosphorus-containing groups 8.4411E-3 7 420 3 6292
    protein tag 8.8705E-3 7 8 1 6292
    protein kinase activator activity 9.9746E-3 7 9 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle