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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Ist3. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BUD13
  • nucleus
  • mRNA export from nucleus
  • cellular bud site selection
  • nuclear mRNA splicing, via spliceosome
  • molecular_function
  • CAR2
  • nucleus
  • cytoplasm
  • arginine catabolic process
  • ornithine-oxo-acid transaminase activity
  • CPR1
  • nucleus
  • mitochondrion
  • histone deacetylase complex
  • ascospore formation
  • protein metabolic process
  • peptidyl-prolyl cis-trans isomerase activity
  • DED81
  • cytoplasm
  • asparaginyl-tRNA aminoacylation
  • ATP binding
  • asparagine-tRNA ligase activity
  • IST3
  • U2 snRNP
  • mRNA export from nucleus
  • spliceosome assembly
  • nuclear mRNA splicing, via spliceosome
  • nucleic acid binding
  • nucleotide binding
  • first spliceosomal transesterification activity
  • RNA binding
  • PGM2
  • cytosol
  • response to temperature stimulus
  • energy reserve metabolic process
  • UDP-glucose metabolic process
  • trehalose biosynthetic process
  • alcohol metabolic process
  • glucose metabolic process
  • cellular calcium ion homeostasis
  • vacuolar protein catabolic process
  • carbohydrate metabolic process
  • glycogen biosynthetic process
  • glucose 6-phosphate metabolic process
  • cellular carbohydrate metabolic process
  • galactose catabolic process
  • glucose 1-phosphate metabolic process
  • cellular cation homeostasis
  • phosphoglucomutase activity
  • SAH1
  • cytoplasm
  • methionine metabolic process
  • selenocysteine metabolic process
  • adenosylhomocysteinase activity
  • SSZ1
  • cytoplasm
  • regulation of translational fidelity
  • translation
  • unfolded protein binding
  • YDR341C
  • cytoplasm
  • mitochondrion
  • arginyl-tRNA aminoacylation
  • translation
  • arginine-tRNA ligase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cellular amino acid metabolic process 1.08E-4 9 199 4 6292
    cellular amine metabolic process 1.6531E-4 9 222 4 6292
    amine metabolic process 2.3463E-4 9 243 4 6292
    cellular amino acid and derivative metabolic process 2.3463E-4 9 243 4 6292
    organic acid metabolic process 7.8529E-4 9 333 4 6292
    oxoacid metabolic process 7.8529E-4 9 333 4 6292
    carboxylic acid metabolic process 7.8529E-4 9 333 4 6292
    cellular ketone metabolic process 9.0809E-4 9 346 4 6292
    primary metabolic process 9.2081E-4 9 2896 9 6292
    tRNA aminoacylation for protein translation 9.3856E-4 9 33 2 6292
    tRNA aminoacylation 9.3856E-4 9 33 2 6292
    amino acid activation 9.3856E-4 9 33 2 6292
    selenocysteine metabolic process 1.4304E-3 9 1 1 6292
    asparaginyl-tRNA aminoacylation 1.4304E-3 9 1 1 6292
    selenium metabolic process 1.4304E-3 9 1 1 6292
    metabolic process 2.004E-3 9 3157 9 6292
    small molecule metabolic process 2.1047E-3 9 760 5 6292
    cellular nitrogen compound metabolic process 2.8378E-3 9 1770 7 6292
    arginine catabolic process 2.859E-3 9 2 1 6292
    glucose 1-phosphate metabolic process 2.859E-3 9 2 1 6292
    arginyl-tRNA aminoacylation 2.859E-3 9 2 1 6292
    glucose 6-phosphate metabolic process 2.859E-3 9 2 1 6292
    nitrogen compound metabolic process 3.0588E-3 9 1791 7 6292
    mRNA export from nucleus 3.9454E-3 9 68 2 6292
    mRNA transport 3.9454E-3 9 68 2 6292
    UDP-glucose metabolic process 4.2857E-3 9 3 1 6292
    RNA export from nucleus 5.4243E-3 9 80 2 6292
    RNA transport 5.5575E-3 9 81 2 6292
    nucleic acid transport 5.5575E-3 9 81 2 6292
    establishment of RNA localization 5.5575E-3 9 81 2 6292
    RNA localization 7.1217E-3 9 92 2 6292
    galactose catabolic process 7.1338E-3 9 5 1 6292
    nucleobase, nucleoside, nucleotide and nucleic acid transport 7.7349E-3 9 96 2 6292
    nuclear mRNA splicing, via spliceosome 8.2102E-3 9 99 2 6292
    RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 8.3715E-3 9 100 2 6292
    trehalose biosynthetic process 8.5551E-3 9 6 1 6292
    glycoside biosynthetic process 8.5551E-3 9 6 1 6292
    disaccharide biosynthetic process 8.5551E-3 9 6 1 6292
    nuclear export 8.8641E-3 9 103 2 6292
    RNA splicing, via transesterification reactions 9.541E-3 9 107 2 6292
    nucleotide-sugar metabolic process 9.9746E-3 9 7 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    aminoacyl-tRNA ligase activity 1.245E-3 9 38 2 6292
    ligase activity, forming carbon-oxygen bonds 1.245E-3 9 38 2 6292
    ligase activity, forming aminoacyl-tRNA and related compounds 1.245E-3 9 38 2 6292
    trialkylsulfonium hydrolase activity 1.4304E-3 9 1 1 6292
    ornithine-oxo-acid transaminase activity 1.4304E-3 9 1 1 6292
    adenosylhomocysteinase activity 1.4304E-3 9 1 1 6292
    phosphoglucomutase activity 2.859E-3 9 2 1 6292
    arginine-tRNA ligase activity 2.859E-3 9 2 1 6292
    asparagine-tRNA ligase activity 2.859E-3 9 2 1 6292
    nucleotide binding 2.9832E-3 9 59 2 6292
    isomerase activity 3.186E-3 9 61 2 6292
    hydrolase activity, acting on ether bonds 4.2857E-3 9 3 1 6292
    first spliceosomal transesterification activity 8.5551E-3 9 6 1 6292
    catalytic activity 9.6054E-3 9 2150 7 6292
    intramolecular transferase activity, phosphotransferases 9.9746E-3 9 7 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle